Using quetiapine instead of meto for sn method?

[erlendl03]

Meto is too hard to get hold of when I already have quetiapine - I read that the important thing is that it's a dopamine blocker which quetiapine is. But quetiapine also has a very short half life so I'm wondering if that should change how I go about it, and what doses I should take. I already have the sn and I have 28 50mg quetiapine tablets. Any help would be appreciated.

 

[mathieu]

I have heard it said that dosages below 400mg a day do not block dopamine.

 

[CyanideSoup]

I have heard it said that dosages below 400mg a day do not block dopamine.

That's will explain why I vomited the first time then! I didn't know this

 

[BPD_LE]

I have heard it said that dosages below 400mg a day do not block dopamine.

Do you have a source for this statement please?

Meto is too hard to get hold of when I already have quetiapine - I read that the important thing is that it's a dopamine blocker which quetiapine is. But quetiapine also has a very short half life so I'm wondering if that should change how I go about it, and what doses I should take. I already have the sn and I have 28 50mg quetiapine tablets. Any help would be appreciated.

Quetiapine can be used instead of meto. The dose needed will depend on whether you take it regularly, the dose you're prescribed and your weight.

 

[erlendl03]

Do you have a source for this statement please?

Quetiapine can be used instead of meto. The dose needed will depend on whether you take it regularly, the dose you're prescribed and your weight.

I take 25mg every night and weigh just under 8 stone - how do I work out how much to take? If mathieu is right, it sounds like it would be simpler to take one large dose a while before the sn. What resource can I use to work these things out? Timing etc.

 

[Girobatol]

One user here used quetiapine before the SN and seems shes gone.

 

[k75]

The most important benefit of Meto is it helps empty the stomach faster. This is why it's the preferred antiemetic. Not saying you can't substitute, just wanted to make sure all the facts were out there.

 

[redbull]

@erlendl03 I would also like to know about the quetiapine (Seroquel). I don't take it but i have some 200mg tablets.

 

[mathieu]

Do you have a source for this statement please?

Quetiapine can be used instead of meto. The dose needed will depend on whether you take it regularly, the dose you're prescribed and your weight.

It's just something that I've often read on mental illness forums, they are usually knowledgeable about the pharmacology of psych meds. It makes sense because the minimum dosage for psychosis/mania is 400mg and the effect of antipsychotics that helps psychosis/mania is supposed to be dopamine blockade. Lower doses are used for anxiety, sleep and depression.

ETA: I haven't made much effort to search but on the wikipedia page for quetiapine it says "At very low doses, quetiapine acts primarily as a histamine receptor blocker (antihistamine) and α1-adrenergic blocker. When the dose is increased, quetiapine activates the adrenergic system and binds strongly to serotonin receptors and autoreceptors. At high doses, quetiapine starts blocking significant amounts of dopamine receptors.[49][60] Off-label prescriptions, e.g. for chronic insomnia, of low-dose quetiapine is not recommended due to the harmful side-effects.[61] "

 

[BPD_LE]

One user here used quetiapine before the SN and seems shes gone.

She took Quetiapine regularly and a dose lower than 400mg at the end. She did not vomit.

It's just something that I've often read on mental illness forums, they are usually knowledgeable about the pharmacology of psych meds. It makes sense because the minimum dosage for psychosis/mania is 400mg and the effect of antipsychotics that helps psychosis/mania is supposed to be dopamine blockade. Lower doses are used for anxiety, sleep and depression.

ETA: I haven't made much effort to search but on the wikipedia page for quetiapine it says "At very low doses, quetiapine acts primarily as a histamine receptor blocker (antihistamine) and α1-adrenergic blocker. When the dose is increased, quetiapine activates the adrenergic system and binds strongly to serotonin receptors and autoreceptors. At high doses, quetiapine starts blocking significant amounts of dopamine receptors.[49][60] Off-label prescriptions, e.g. for chronic insomnia, of low-dose quetiapine is not recommended due to the harmful side-effects.[61] "

People with psychosis are often on higher doses than people with say BPD who use it as a mood stabiliser. It makes sense the higher the dose the more dopamine is blocked. I've been on a dose lower than 400mg for 10 years and I believe it works as an AE for me. The member @Girobatol mentioned was also on a regular long-term dose lower than 400mg and did not vomit. I'll do more research.
If you're not taking it regularly, 400mg is likely to knock you out before you can get anywhere near the SN.

 

[Ratbat]

U woulf.need a fuk load of quetiapine

 

[Timectb40]

Would a 100mg quetiapine/suraquel be enough? Thats all I take per night? How many days of taking 300 to 400 mg per day would you need to take in a row to be an effective anenimic ??? Thanks