PPeH no longer recommends antacids for SN because it lowers the pH environment of your stomach. Ideally you want a low pH environment for your stomach because of the way SN interacts with acids, the more acid there is, the quicker SN will knock you out.
Sadly I think the same would be for PPIs, they just go about changing acid in a different way (antacids just almost/completely disable all your pumps from pumping out acid for a couple of hours, PPIs either reduces the amount of acids your pumps can send out at a time or turns off just a few at a time).
If you don't mind me asking, do you know what kind of PPI you're on? I used to suffer from gastroesophageal reflux disease, it is entirely possible to cure yourself of GERD because I no longer feel it, but I think the kind of PPI your doctor puts you on can make a big difference on how easy it is to get over GERD.
They first put me on Omeprazole, that's usually the first kind doctors will try to put you on. They were absolute crap for me. I'd only feel slightly better after taking them for 6 days, then sadly feel much worse after taking another on the 7th day. And you know how much of a bastard most doctors can be, one of them tried keeping me on Omeprazole for 2 months. While it eventually got rid of the burning sensation, it was merely replaced with a terrible swollen sensation.
In the end I had to resort to lying to a different doctor saying that I was on 60mg of Omeprazole for 9 days (when I really have only ever taken that much for 2 days) and that I was starting to lose weight. He moved me onto Lansoprazole 20mg once a day, and my god Lansoprazole worked like a dream. I was actually starting to feel better after 3 days, and when I finished the whole course of 28 days my GERD was completely gone (I still had a few extra Lansoprazole just to ween myself off of them because it's recommended to do that with PPIs to avoid acid rebound).
