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madscotsman

madscotsman

Member
Nov 11, 2024
52
Which would be the best for painkilling regardless of potency, maybe certain one for certain types of pain?
 
identity0

identity0

.
Sep 25, 2024
368
Tramadol is the weakest of the three. The dose limit is reached quickly before it becomes uncomfortable and can induce seizures. It is simply too weak for some forms of pain. It has antidepressant-related effects which mean it can have prolonged anti-depressant-like discontinuation/withdrawal symptoms if it is taken for weeks at a time.

Oxycodone is stronger, and more of a classic opioid. Tolerance can build quickly and dosage can be raised a lot if needed. it is typically much more expensive to maintain a habit with it on the black market but many people find it to be more euphoric. Those properties i suppose could make it riskier for addiction.

It seems tapentadol is comparable in strength to oxycodone but has similar characteristics to tramadol; I am not really familiar with it and havent tried it.

Individual response varies a lot, so in the end it may come down to the individual. Some people feel nauseous on oxycodone, some have barely any effect from tramadol. I happen to have a strong, long-lasting effect from tramadol so i'd take that if it were enough for my pain. For stronger pain i'd take oxycodone or try tapentadol.

I am not sure but neuropathic pain might be one of the only cases afaik where oxycodone might be less effective than tramadol or a different drug called pregabalin. Otherwise i dont think it typically matters where the pain is, just how strong it is
 
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madscotsman

madscotsman

Member
Nov 11, 2024
52
Tramadol is the weakest of the three. The dose limit is reached quickly before it becomes uncomfortable and can induce seizures. It is simply too weak for some forms of pain. It has antidepressant-related effects which mean it can have prolonged anti-depressant-like discontinuation/withdrawal symptoms if it is taken for weeks at a time.

Oxycodone is stronger, and more of a classic opioid. Tolerance can build quickly and dosage can be raised a lot if needed. it is typically much more expensive to maintain a habit with it on the black market but many people find it to be more euphoric.

It seems tapentadol is comparable in strength to oxycodone but has similar characteristics to tramadol; I am not really familiar with it and havent tried it.

Individual response varies a lot, so in the end it may come down to the individual. Some people feel nauseous on oxycodone, some have barely any effect from tramadol. I happen to have a strong, long-lasting effect from tramadol so i'd take that if it were enough for my pain. For stronger pain i'd take oxycodone or try tapentadol.

I am not sure but neuropathic pain might be one of the only cases afaik where oxycodone might be less effective than tramadol or a different drug called pregabalin. Otherwise i dont think it typically matters where the pain is, just how strong it is
Thank you man, useful stuff so I'll go with oxycodone possibly
 
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lifeisbutadream

Warlock
Oct 4, 2018
789
Tramadol is the weakest of the three. The dose limit is reached quickly before it becomes uncomfortable and can induce seizures. It is simply too weak for some forms of pain. It has antidepressant-related effects which mean it can have prolonged anti-depressant-like discontinuation/withdrawal symptoms if it is taken for weeks at a time.

Oxycodone is stronger, and more of a classic opioid. Tolerance can build quickly and dosage can be raised a lot if needed. it is typically much more expensive to maintain a habit with it on the black market but many people find it to be more euphoric. Those properties i suppose could make it riskier for addiction.

It seems tapentadol is comparable in strength to oxycodone but has similar characteristics to tramadol; I am not really familiar with it and havent tried it.

Individual response varies a lot, so in the end it may come down to the individual. Some people feel nauseous on oxycodone, some have barely any effect from tramadol. I happen to have a strong, long-lasting effect from tramadol so i'd take that if it were enough for my pain. For stronger pain i'd take oxycodone or try tapentadol.

I am not sure but neuropathic pain might be one of the only cases afaik where oxycodone might be less effective than tramadol or a different drug called pregabalin. Otherwise i dont think it typically matters where the pain is, just how strong it is


"I am not sure but neuropathic pain might be one of the only cases afaik where oxycodone might be less effective than tramadol or a different drug called pregabalin."


Neuropathic pain. Nothing really helps, but yes tramadol is a tiny bit more effective than the others. Oxycodone and similar make it even worse.
 
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