Starting Mirtazapine

[InezSerrano]

Does anyone have experience with this? I have a depression, anxiety, and insomnia diagnosis, so it seems good. My doctor is starting me on it.

 

[Sherri]

Never took this type of med, hope it works for you, read well the leaflet inside , all of it very well. Usually a anti Depressant takes 3 weeks to kick in. Wish you good luck. I'm sure you will have comments from someone who takes it.

 

[InezSerrano]

Never took this type of med, hope it works for you, read well the leaflet inside , all of it very well. Usually a anti Depressant takes 3 weeks to kick in. Wish you good luck. I'm sure you will have comments from someone who takes it.

Thank you for the advice.

 

[messy]

I've tried 20+ antidepressants/psychiatric medications and Mirtazapine is the one I've had the most success with. It works relatively quickly and makes a really noticeable difference in my depression AND anxiety levels. Unfortunately, it is always short lived for me - all three times I've tried it, the results have been quick and dramatic, but also pretty temporary. But I DON'T think that's true for most people! So I hope that you have similar results to mine, but that they are long-term.

 

[InezSerrano]

I've tried 20+ antidepressants/psychiatric medications and Mirtazapine is the one I've had the most success with. It works relatively quickly and makes a really noticeable difference in my depression AND anxiety levels. Unfortunately, it is always short lived for me - all three times I've tried it, the results have been quick and dramatic, but also pretty temporary. But I DON'T think that's true for most people! So I hope that you have similar results to mine, but that they are long-term.

Okay, cool! Hopefully it doesn't stop working for me, lol. (fingers crossed). I'm sorry it doesn't work for you.

 

[messy]

Okay, cool! Hopefully it doesn't stop working for me, lol. (fingers crossed). I'm sorry it doesn't work for you.

lol thanks and I REALLY hope it works for you! It was so CLOSE to working for me!

 

[Sherri]

I've tried 20+ antidepressants/psychiatric medications and Mirtazapine is the one I've had the most success with. It works relatively quickly and makes a really noticeable difference in my depression AND anxiety levels. Unfortunately, it is always short lived for me - all three times I've tried it, the results have been quick and dramatic, but also pretty temporary. But I DON'T think that's true for most people! So I hope that you have similar results to mine, but that they are long-term.

Same as me around 20 and when I was losing hope, got one (not this) that worked for me. I'm happy you finally also find one, this, who works for you.

Thank you for the advice.

You're welcome, keep us posted on how you feeling.

 

[SovietSuicide]

Worked better than prozac for me but still not enough for me to give up my recreational drug use which I use to cope and stay on the prescription.

Makes you HUNGRY, I wanted a 3 course meal every 20 minutes, good if you're underweight, bad if you're overweight. Good luck.

 

[InezSerrano]

Worked better than prozac for me but still not enough for me to give up my recreational drug use which I use to cope and stay on the prescription.

Makes you HUNGRY, I wanted a 3 course meal every 20 minutes, good if you're underweight, bad if you're overweight. Good luck.

You have to stop recreational drug use? Wdym? It's not an SSRI/SNRI, it should be fine, right?

 

[SovietSuicide]

You have to stop recreational drug use? Wdym? It's not an SSRI/SNRI, it should be fine, right?

You don't have to but if I'm using then my two mental states are basically high or not high, no point in taking Mirt because if I'm feeling bad I'll just do more drugs.

 

[InezSerrano]

You have to stop recreational drug use? Wdym? It's not an SSRI/SNRI, it should be fine, right?

Oh, I found it may be the same as other traditional anti depressants, a risk of serotonin syndrome with drugs like mdma or lsd. I need to read a bit more, some people say it just dulls effects.

 

[GentleJerk]

I tried it before but it was never prescribed for me. My friend gave me some to sleep. It knocked me right out. I had really crazy vivid dreams from it, overslept (asleep for 12+ hours!) and woke up the next day feeling really vacant and zombie like with mild visual distortion. Mirtazapine dreams are a thing, look it up.

It helped me go to sleep but I didn't enjoy it and never tried it again.

Not to put you off, that's just my experience. Plus apparently, these drugs sometimes work better after taking them for longer and you can adjust to the heavy sedating effects and learn to operate on them.

 

[Sherri]

Just a follow up, is everything ok with the med since you started to it take yesterday?

 

[Slaanesh]

Does anyone have experience with this? I have a depression, anxiety, and insomnia diagnosis, so it seems good. My doctor is starting me on it.

Been on it for around 4 or 5 weeks now, 30 mg dose.

I've found that if you're a bad sleeper they really help, take them just before you go to bed, and they knock you right out, which is quite a nice benefit.
Although instead of making me feel like a zombie which a lot of antidepressants can do, instead I find that I'm extremely irritable on them, like things will just piss me off way too easily.

So pros and cons like with most meds, they'll always work differently for different bodies mind, so until you yourself have been on them for a while I wouldn't take personal anecdotes too seriously.

 

[InezSerrano]

Been on it for around 4 or 5 weeks now, 30 mg dose.

I've found that if you're a bad sleeper they really help, take them just before you go to bed, and they knock you right out, which is quite a nice benefit.
Although instead of making me feel like a zombie which a lot of antidepressants can do, instead I find that I'm extremely irritable on them, like things will just piss me off way too easily.

So pros and cons like with most meds, they'll always work differently for different bodies mind, so until you yourself have been on them for a while I wouldn't take personal anecdotes too seriously.

I usually take melatonin, usually sleep for 9.5 hours, on mirtazapine I slept for 17. I also took ketamine yesterday though, so it's hard to say what caused it

Just a follow up, is everything ok with the med since you started to it take yesterday?

everything is fine, feel kind of out of it but that's normal for me. also slept a lot, but there are other factors, and i've slept for way too long before many times too.

 

[kappa]

The oversleeping usually goes away after a week or so. The first few days are rough because you can get that pill hangover feeling.

The lower dose is the most sedating. I stayed on the low dose for years just for that.

It gave me insane munchies.. just be careful with those. You feel fine, then get up to make something to eat and can all of a sudden get super dizzy. The NP warned me before I started taking it. She had a woman who fell into her glass coffee table getting up to get something to eat.

One night I made pasta, had it all ready.. ended up laying on the kitchen floor for a while before crawling to my bed. Never got the pasta- plated it and everything!

 

[Onthe29th]

Interesting, it's also helps people fall asleep and it can increase apetite. Hopefully everything works out.

 

[Ethereal Knight]

I wanna try Mirtazapine or low-dose Doxepin for insomnia.
I have had chronic insomnia for more than a decade, and I thought I solved the problem with Amitriptyline, until it stopped working three years after I started taking it.
Then I tried Trazodone, but found it to be too weak for me, especially considering my insomnia is maintainance insomnia (I wake up too early and become constantly fatigued the next day).
I heard about low-dose Doxepin in the treatment of insomnia, that it has great cost:benefit ratio, with little to no side effects or adverse reactions, but I also heard that it's too weak compared to other drugs (like mirtazapine)

Does someone here have an experience with sleeping pills that work for chronic insomnia? Doxepin, Amitriptyline, Trazodone, Paroxetin, Promethazine, Eszopiclone, Olanzapine...
I have been having a hard time staying on one drug without it gradually losing its eficaciousness over time.

But going back to the topic, about mirtazapine and one of its main side effects, weight gain:
I have an ideia what's like to gain weight from a drug, as Amitriptyline did it to me.
Mirtazapine does seem to cause it, no wonder why they prescript this drug for underweight people, anorexics etc. Its weight gain seems to be continous and does not go away with long-term treatment. It also causes day-time sleepiness and fatigue.
Please, be careful. If you gain too much body fat and reach your personal fat threshold, you can become insulin resistant, and eventually diabetic. Or you may manifest other signs of the metabolic syndrome.
These metabolic conditions can actually worsen depression. And they can happen at any BMI, at any weight.
Some lab tests can be used to detect diabetes early, like:
Homa-IR test;
Fasting insulin (ideally less than 5, the lower the better. if it's higher than 10, you have some degree of insulin resistance [IR]);
Fasting glucose;
Fasting triglicerydes (ideally less than 70. if higher than 100, you have some degree of IR) etc...

If you can figure out a way to sleep well without this kind of drug, and your main goal is to treat depression, not insomnia, then maybe there are better drugs than mirtazapine, drugs with less side-effects or more tolerable side-effect profile, but I'm not a doctor, this is not advice and you have to check that with your doctor.

 

[Sherri]

It's been a few days now M how you feeling? All good on your side?

 

[Foresight]

I hope your treatments are going good and everything's going okay with the therapist.

 

[InezSerrano]

I decided to stop taking it. I can't do MDMA because of the risk of serotonin syndrome, so I start thinking about trying Cocaine or maybe GHB or something to see if it can fill that desire, but everything I could do instead of MDMA is more risky. So, is being less depressed worth the risk of these other drugs? I don't know. I should probably talk to my doctor about it.

 

[TooConscious]

I think b cuse depending on your gender, height and frame you gain anywhere from 200-700lbs in the first month, therefor your dopamine and serotonin naturally increase due to increased body size, so it's a very effective drug.

 

[theloserestloser]

this is late now but i was put on mirtazapine due to my history of serotonin syndrome and only took the lowest dose for 4-5 months. the withdrawals screwed me up for weeks. being on the medication itself was fine but the withdrawals were horrific

 

[xtal666]

I remember it was a very very nice antidepressant but the weightgain omg. Good luck to you!

 

[Julgran]

I'm also on a daily Mirtazapine regiment, but my weight gain is mainly caused by my own "nothing matters anymore, so why not eat?" mentality. Despite that, I try to eat healthy, but the problem is wanting and feel motivated to eath healthy.

 

[kappa]

I decided to stop taking it. I can't do MDMA because of the risk of serotonin syndrome, so I start thinking about trying Cocaine or maybe GHB or something to see if it can fill that desire, but everything I could do instead of MDMA is more risky. So, is being less depressed worth the risk of these other drugs? I don't know. I should probably talk to my doctor about it.

Drugs like that can only make your depression worse, don't you think?

I still regret ever trying MDMA.

I wanna try Mirtazapine or low-dose Doxepin for insomnia.
I have had chronic insomnia for more than a decade, and I thought I solved the problem with Amitriptyline, until it stopped working three years after I started taking it.
Then I tried Trazodone, but found it to be too weak for me, especially considering my insomnia is maintainance insomnia (I wake up too early and become constantly fatigued the next day).
I heard about low-dose Doxepin in the treatment of insomnia, that it has great cost:benefit ratio, with little to no side effects or adverse reactions, but I also heard that it's too weak compared to other drugs (like mirtazapine)

Does someone here have an experience with sleeping pills that work for chronic insomnia? Doxepin, Amitriptyline, Trazodone, Paroxetin, Promethazine, Eszopiclone, Olanzapine...
I have been having a hard time staying on one drug without it gradually losing its eficaciousness over time.

But going back to the topic, about mirtazapine and one of its main side effects, weight gain:
I have an ideia what's like to gain weight from a drug, as Amitriptyline did it to me.
Mirtazapine does seem to cause it, no wonder why they prescript this drug for underweight people, anorexics etc. Its weight gain seems to be continous and does not go away with long-term treatment. It also causes day-time sleepiness and fatigue.
Please, be careful. If you gain too much body fat and reach your personal fat threshold, you can become insulin resistant, and eventually diabetic. Or you may manifest other signs of the metabolic syndrome.
These metabolic conditions can actually worsen depression. And they can happen at any BMI, at any weight.
Some lab tests can be used to detect diabetes early, like:
Homa-IR test;
Fasting insulin (ideally less than 5, the lower the better. if it's higher than 10, you have some degree of insulin resistance [IR]);
Fasting glucose;
Fasting triglicerydes (ideally less than 70. if higher than 100, you have some degree of IR) etc...

If you can figure out a way to sleep well without this kind of drug, and your main goal is to treat depression, not insomnia, then maybe there are better drugs than mirtazapine, drugs with less side-effects or more tolerable side-effect profile, but I'm not a doctor, this is not advice and you have to check that with your doctor.

I have very adverse side effects to some drugs.. so this might not be that helpful. But, I'd say Mirtazapine is worth trying.

I was taking Doxepin for a while, but for me it didn't do enough alone. I've heard Olanzapine works for helping you fall asleep but personally it didn't do anything to me. I did notice it helped with my overall nausea throughout the day.

Mirtazapine didn't cause me a huge weight gain. But it does increase your appetite. I would get "munchies" after my nightly dose. Sometimes I still stayed up too late, because I would be staying up to eat. It can get annoying. I started taking it again recently, but I do feel pretty fatigued all day.

The only thing that helps me sleep-wise are benzos I know it's not ideal but nothing else works.

 

[bad luck]

It felt weird to me. He had tremors in his hands and "sparks" in the brain (at least he felt that way) they changed him to trazodone

 

[Sherri]

So you stopped? Yeah doing both drugs is prob not a good idea.

 

[InezSerrano]

So you stopped? Yeah doing both drugs is prob not a good idea.

Yeah... IDK. I'm talking to my doctor about it on the 17th.

 

[Sherri]

Yeah... IDK. I'm talking to my doctor about it on the 17th.

Are you going to mention the mdma?