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A

Art92

Member
Nov 14, 2021
60
is encephalopathy possible after unsuccessful sn intake?
 
freelifexit

freelifexit

Specialist
Nov 7, 2021
391
users write that there is no consequences, but those who could have consequences will no longer write messages due to brain damage
here is article on russian: https://neurorhb.com/ru/anoxia/
 
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A

Art92

Member
Nov 14, 2021
60
users write that there is no consequences, but those who could have consequences will no longer write messages due to brain damage
here is article on russian: https://neurorhb.com/ru/anoxia/
I just have brain damage from bad ecstasy use. I struggled with symptoms for half a year, but without successfully. There is an opportunity to jump from the 46th floor, but I am very afraid of that. And I'm afraid that sn's failed attempt will do even more harm
 
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freelifexit

freelifexit

Specialist
Nov 7, 2021
391
no one guarantees that it is safe, there are cases when there were no consequences after trying SN, but as I wrote earlier, those who have consequences after an unsuccessful attempt may not be able to use computer due to brain damage

what exactly happened to the brain after ecstasy?
 
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K

Kennish

Specialist
Aug 17, 2021
379
I have never heard of people not recovering after SN attempt. Never heard of what you're writing about brain damage
 
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blueclover_.

blueclover_.

Better Never to Have Been: 2006, David Benatar
Oct 11, 2021
668
We haven't done enough studies to explore all the possibilities of SN poisoning, but so far there are no reported cases suggesting any problem with the brain solely due to hypoxia with SN.
 
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S

sandalphon

Student
Aug 19, 2021
126
no one guarantees that it is safe, there are cases when there were no consequences after trying SN, but as I wrote earlier, those who have consequences after an unsuccessful attempt may not be able to use computer due to brain damage

what exactly happened to the brain after ecstasy?
Where's your proof for this? Who are these members with brain damage because of unsuccessful SN ctb?
 
freelifexit

freelifexit

Specialist
Nov 7, 2021
391
Where's your proof for this? Who are these members with brain damage because of unsuccessful SN ctb?
proof is the article that I pointed out, those whose brain is injured are not able to write anything, so we will not find out about them
 
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P

PassingThrough

Member
Nov 15, 2021
56
If there had been a case where SN ingestion resulted in survival but with brain damage, I'm pretty sure doctors and journalists alike would have pounced on this as an opportunity to deter people from ctbing with SN: "Look at this young guy who took SN! He had his whole life ahead of him and now he's a disabled man confined to a wheelchair. Don't do it!". This doesn't prove it never happened, but it is probably a rare occurrence.
 
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aminend

aminend

Warlock
May 24, 2020
746
users write that there is no consequences, but those who could have consequences will no longer write messages due to brain damage
here is article on russian: https://neurorhb.com/ru/anoxia/
Sn doesn't cause permanent damage. There are many many articles in witch successful and failed attempts have been described. Don't spread fake information.

Ur shared link isn't about SN and even isn't related to suicide.
 
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shy

shy

Student
Aug 23, 2020
122
Does anyone actually know why survivors of SN poisoning don't seem to show signs of brain damage, compared to survivors of CO poisoning?

You can reverse methaemoglobin to normal haemoglobin pretty quickly using methylene blue, while there's no quick way to turn carboxyhaemoglobin into normal haemoglobin.

But you'll get hypoxic and die using both methods, so why is it that SN either kills or that you're able to make a full recovery? Only thing I can think of is that the rate of oxygen deprivation of the brain is somehow different. I think I read somewhere that the nitrite converts to nitric oxide, increasing blood flow in and to the brain and some other protective effects.
 
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S

sandalphon

Student
Aug 19, 2021
126
Sn doesn't cause permanent damage. There are many many articles in witch successful and failed attempts have been described. Don't spread fake information.

Ur shared link isn't about SN and even isn't related to suicide.
Almost every post by that member is SN fear mongering. I would REALLY take everything they say with a grain of salt.
 
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blueclover_.

blueclover_.

Better Never to Have Been: 2006, David Benatar
Oct 11, 2021
668
Does anyone actually know why survivors of SN poisoning don't seem to show signs of brain damage, compared to survivors of CO poisoning?

You can reverse methaemoglobin to normal haemoglobin pretty quickly using methylene blue, while there's no quick way to turn carboxyhaemoglobin into normal haemoglobin.

But you'll get hypoxic and die using both methods, so why is it that SN either kills or that you're able to make a full recovery? Only thing I can think of is that the rate of oxygen deprivation of the brain is somehow different. I think I read somewhere that the nitrite converts to nitric oxide, increasing blood flow in and to the brain and some other protective effects.
This. The consumed SN turns into NO and protects the brain from Hypoxia-Ischaemic injury up to the moment of death. Although it is still an ongoing study and they used very little amount of SN to test it with rats brains.
 
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shy

shy

Student
Aug 23, 2020
122
This. The consumed SN turns into NO and protects the brain from Hypoxia-Ischaemic injury up to the moment of death. Although it is still an ongoing study and they used very little amount of SN to test it with rats brains.

It's quite amazing how that works, is the heart protected the same way? Haven't heard of anyone having heart problems after surviving SN either, even though it's also one of the first organs hit with ischaemia under hypoxic conditions.
 
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blueclover_.

blueclover_.

Better Never to Have Been: 2006, David Benatar
Oct 11, 2021
668
It's quite amazing how that works, is the heart protected the same way? Haven't heard of anyone having heart problems after surviving SN either, even though it's also one of the first organs hit with ischaemia under hypoxic conditions.
Doctors can intentionally use SN to protect the heart, but based on my research if SN is ingested naturally it will only protect the brain tissue. Look at my last thread, there are some sources which include this topic.
 
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lmon

lmon

Specialist
Jan 9, 2022
326
Sn doesn't cause permanent damage. There are many many articles in witch successful and failed attempts have been described. Don't spread fake information.

Ur shared link isn't about SN and even isn't related to suicide.
Chas it not caused organ damage though, or no
It's quite amazing how that works, is the heart protected the same way? Haven't heard of anyone having heart problems after surviving SN either, even though it's also one of the first organs hit with ischaemia under hypoxic conditions.
Have you heard of any organs having problems from it
 
shy

shy

Student
Aug 23, 2020
122
Chas it not caused organ damage though, or no

Have you heard of any organs having problems from it
Haven't heard of anyone having any immediate problems after surviving SN. Doesn't mean that there can't be any problems arising much later, caused by a failed attempt with SN. Not much literature out there on the topic and the anecdotes on here should be taken with a grain of salt.
 
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Shu

Shu

As above, So Below.
Jan 21, 2022
2,487
proof is the article that I pointed out, those whose brain is injured are not able to write anything, so we will not find out about them
I'm pretty sure we will definitely have found out about it or would have been published in article by now
 
SofterSoftest

SofterSoftest

Student
Dec 30, 2021
186
I don't think brain damage with a failed SN attempt is very likely at all, but it is (I think) quite possible to experience other long-term organ damage, including renal failure (possibly liver failure, but there isn't as much literature on this). I worry about renal failure, in particular, because the symptoms of renal dysfunction can actually be quite subdued for a while - it would make sense that many don't feel the impacts of SN poisoning right away. There's also lots of evidence that a diet high in SN is directly linked with cancers of the GI (including esophageal and gastric cancers).

Here's an article on the effect of SN on rat kidneys:
https://doi.org/10.1002/jcb.26611

Anyway, of course I wish none of this were true, because I have SN and really want to CTB. I would love to just be able to take it and get it done. But on the off chance that I survive, I worry about what that would mean for my life until I do get to CTB.
 
Shu

Shu

As above, So Below.
Jan 21, 2022
2,487
proof is the article that I pointed out
How long were they unconscious before being found?
If there had been a case where SN ingestion resulted in survival but with brain damage, I'm pretty sure doctors and journalists alike would have pounced on this as an opportunity to deter people from ctbing with SN: "Look at this young guy who took SN! He had his whole life ahead of him and now he's a disabled man confined to a wheelchair. Don't do it!". This doesn't prove it never happened, but it is probably a rare occurrence.
Right. 100
 
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Cathy Ames

Cathy Ames

Cautionary Tale
Mar 11, 2022
2,109
This. The consumed SN turns into NO and protects the brain from Hypoxia-Ischaemic injury up to the moment of death. Although it is still an ongoing study and they used very little amount of SN to test it with rats brains.
I am curious about these studies with rat brains. Maybe you can give links to the ones you have found that show a lack of injury. On a very cursory google search I'm not seeing this.

Here is an abstract for one where they looked at the brains one hour after administration and found DAMAGE in cerebellar Purkinje cells. "The principal findings in the treated group were that almost all the Purkinje cells showed autolytic changes. Their arrangement as a single layer was also deranged in certain areas. Some areas showed complete loss of Purkinje neurons. Conclusion: Sodium nitrite-induced hypoxia results in severe damage to the Purkinje neurons."


Here is one where, again one hour after administration, they found hypoxic damage (degeneration) in the hippocampus and dentate gyrus.


And there are others. It is not "fear mongering" to tell people that it is a very bad idea to GUARANTEE no damage. A lack of damage certainly seems possible under some circumstances (like if you get help very soon), and perhaps the type of damage seen in these studies is reversible. But I'm not seeing a guarantee even if someone did give an unsourced opinion that this is the case in the suicide wiki.

Come on. The anoxia to the brain and/or heart is the REASON why people die from this stuff. Lack of oxygen causes damage.
 
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Judy Garland

Judy Garland

HoHum
Mar 23, 2022
826
I am curious about these studies with rat brains. Maybe you can give links to the ones you have found that show a lack of injury. On a very cursory google search I'm not seeing this.

Here is an abstract for one where they looked at the brains one hour after administration and found DAMAGE in cerebellar Purkinje cells. "The principal findings in the treated group were that almost all the Purkinje cells showed autolytic changes. Their arrangement as a single layer was also deranged in certain areas. Some areas showed complete loss of Purkinje neurons. Conclusion: Sodium nitrite-induced hypoxia results in severe damage to the Purkinje neurons."


Here is one where, again one hour after administration, they found hypoxic damage (degeneration) in the hippocampus and dentate gyrus.


And there are others. It is not "fear mongering" to tell people that it is a very bad idea to GUARANTEE no damage. A lack of damage certainly seems possible under some circumstances (like if you get help very soon), and perhaps the type of damage seen in these studies is reversible. But I'm not seeing a guarantee even if someone did give an unsourced opinion that this is the case in the suicide wiki.

Come on. The anoxia to the brain and/or heart is the REASON why people die from this stuff. Lack of oxygen causes damage.
And that's how I'll die, thank you very much. Again, no one was saying that anything was guaranteed, but anyone who has failed on here has not reported any brain damage. What the consensus seems to be is that compared to hanging for example, you are less likely to have brain damage with SN. And yes, FreExit or whatever his name is, does fear monger. This is the only stuff he ever posts; he is always negative, and the fact that people from 2021 are calling him out on it proves it. So thanks Cath.
 
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Cathy Ames

Cathy Ames

Cautionary Tale
Mar 11, 2022
2,109
And that's how I'll die, thank you very much. Again, no one was saying that anything was guaranteed, but anyone who has failed on here has not reported any brain damage. What the consensus seems to be is that compared to hanging for example, you are less likely to have brain damage with SN. And yes, FreExit or whatever his name is, does fear monger. This is the only stuff he ever posts; he is always negative, and the fact that people from 2021 are calling him out on it proves it. So thanks Cath.
I think it's important for someone using it to make sure they won't be found and rescued once the effects are well underway. That's what my take home message is, at least in my own mind. I wouldn't try to talk someone out of using this as their method. I believe the ratings it was given in terms of reliability, peacefulness, etc. It's legal. It's affordable. It doesn't take special expertise or equipment. In a perfect world, people would be able to have "support" while using it--the optimal prescribed drugs to go with it and someone present to support/comfort the person while they were puking (if they did) and/or had a high stressful heart rate. I'm definitely NOT trying to scare you into not using it, @Judy_Garland

My only quibble has been the insistence from some people that it is GUARANTEED safe/problem free if someone fails due to getting rescued. I feel the absence of evidence is not the same thing as the evidence of absence as far as that goes. That's all. I'm sorry if I scared you.
 
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freelifexit

freelifexit

Specialist
Nov 7, 2021
391
And that's how I'll die, thank you very much. Again, no one was saying that anything was guaranteed, but anyone who has failed on here has not reported any brain damage. What the consensus seems to be is that compared to hanging for example, you are less likely to have brain damage with SN. And yes, FreExit or whatever his name is, does fear monger. This is the only stuff he ever posts; he is always negative, and the fact that people from 2021 are calling him out on it proves it. So thanks Cath.
I share info from articles (with links).
 
Judy Garland

Judy Garland

HoHum
Mar 23, 2022
826
I think it's important for someone using it to make sure they won't be found and rescued once the effects are well underway. That's what my take home message is, at least in my own mind. I wouldn't try to talk someone out of using this as their method. I believe the ratings it was given in terms of reliability, peacefulness, etc. It's legal. It's affordable. It doesn't take special expertise or equipment. In a perfect world, people would be able to have "support" while using it--the optimal prescribed drugs to go with it and someone present to support/comfort the person while they were puking (if they did) and/or had a high stressful heart rate. I'm definitely NOT trying to scare you into not using it, @Judy_Garland

My only quibble has been the insistence from some people that it is GUARANTEED safe/problem free if someone fails due to getting rescued. I feel the absence of evidence is not the same thing as the evidence of absence as far as that goes. That's all. I'm sorry if I scared you.
You didn't scare me, and neither did Freelifexit. On his other thread, I was merely pointing out that he likes to post all kinds of negative posts. And he did it here, years ago. A lot of people have caught on to that and have blocked him. As I have too.
 
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freelifexit

freelifexit

Specialist
Nov 7, 2021
391
You didn't scare me, and neither did Freelifexit. On his other thread, I was merely pointing out that he likes to post all kinds of negative posts. And he did it here, years ago. A lot of people have caught on to that and have blocked him. As I have too.
Seems you got real butthurt from my posts๐Ÿ˜‚
 
๐Ÿ‘

๐Ÿ‘๏ธ๐Ÿ‘ƒ๐Ÿ‘๏ธ

Enlightened
Aug 14, 2022
1,292
no one guarantees that it is safe, there are cases when there were no consequences after trying SN, but as I wrote earlier, those who have consequences after an unsuccessful attempt may not be able to use computer due to brain damage

what exactly happened to the brain after ecstasy?
You're full of shit.
proof is the article that I pointed out, those whose brain is injured are not able to write anything, so we will not find out about them
You're absolutely full of shit. If anyone ended up brain dead with all the attention being brought towards Sodium Nitrite, we would know by now.
 
freelifexit

freelifexit

Specialist
Nov 7, 2021
391
with all the attention being brought towards Sodium Nitrite
Attention only on this forum, not in the world, scientists don't give a fuck about you.

SN causes methnemoglobinemia in the body, which causes hypoxia, that is, reduced oxygen in the blood, which can lead to brain damage, despite the created NO.

I will not respond to new comments here, because expect only emotional reactions from SN fanatics.
 

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