Method Salicylate Poisoning?

[Soul]

Can any of you fine patient learned people explain what death by salicylate OD is like? I've read medical-journal descriptions but they don't communicate much to me in terms of what the person is likely to experience on the way to the exit. As in is it quick? painful? awful in other ways? What happens if the person is interrupted - is it reversible? does it leave lasting damage? And so on.

I know (or think I know) that oils like Betula lenta or wintergreen are more toxic in dermal applications than they are orally. So I guess for the sake of the discussion we could assume dermal application of undiluted wintergreen oil.

Here are a few articles about it:

Salicylate Toxicity from Ingestion and Continued Dermal Absorption

www.ncbi.nlm.nih.gov

Aspirin and Other Salicylate Poisoning - Injuries; Poisoning - MSD Manual Professional Edition

Aspirin and Other Salicylate Poisoning - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional Version.

www.msdmanuals.com

Salicylate poisoning - Wikipedia

en.m.wikipedia.org

If I'm reading the wikipedia chart right, 30-50 ml of undiluted wintergreen oil would be enough for an adult. It's not obviously very easy to achieve dermal absorption of that much at once, but ...

The first article, about the combined oral and dermal use, sounds like the man was unconscious most of the time after he threw up. But it also sounds like adding some (oral) sedatives wouldn't be a mistake.

I loathe the smell of methyl salicylate but other than that, does it seem like a feasible method?

 

[Soul]

Bumping gently, in case any of our esteemed kind and patient pharmacology types are within bumping distance ... Thanks!

 

[Soul]

Patiently bumping.

Apparently applying it regularly and then indulging in a large stat dose is a way people have died from it, but 1] how would one maximise the efficiency, and 2] how lousy would one feel on the way out?

Thanks!

 

[overandout]

Hazards and Cautions
Do not use in the presence of and for children aged under 7 years old.

Do not use for pregnant women or if breastfeeding, or for people with a history of convulsive disorders, epilepsy or for people who are allergic to essential oils and salicylates. Do not use if you are allergic to salicylates. For people receiving medical treatment and for children, seek the advice of a health specialist.


Read more at https://www.boots.com/puressentiel-...ntial-oil---10ml-10258136#5dB7HpbdMTxYoU2m.99

Not a pharmacist but wondering if you would get seizures from this?
I hope someone helps you out with this

 

[Soul]

Thank you, @overandout. I think seizures are part of it but if I'm unconscious I don't mind.

I hope someone with medical or pharmacological insights can translate the articles into practical ctb terms. What is it like to die this way?

 

[chrijo]

Hi @Soul :-)

I didn't read your linked article but I hope this helps you anyway.

If you overdose salicylates, your blood PH will drop drastically. You're falling into a metabolic acidosis. Read about it if you want to know more.

Your body will try to get rid of CO2 with faster breathing. I've seen this a few times, looks really scary. The people are also approachable and scared to death, most of them vomiting and have an increased tendency to cramp. A metabolic acidosis affects the entire body, your heart becomes weaker and later your breathing slows down and your circulatory collapse. Then coma, then death due to multi organ dysfunction.

Don't try to OD on aspirin, wintergreen oil or other salicylates, it's not peaceful.

 

[Soul]

Thank you, @chrijo! I reckoned there must be something awful about it (in addition to the smell, I mean).

But can I have a few more questions anyway, just to be thorough?


How long would it take to die of methyl salicylate poisoning, assuming a major dermal application of wintergreen oil - say 100 ml?

Could one take benzos to stay unconscious for the scary parts?

Thanks again! And the anti-recommendation is duly noted.

Thanks!

 

[chrijo]

I think dermal overdose is unlikely unless you do it over a longer period of time. Salicylates accumulate in the body over time. It only becomes really dangerous when a larger amount is taken orally or other ways like open wounds etc.

Benzodiazepines can relieve symptoms, but they are not strong enough. They do not relieve any pain, you'll probably wake up in panic and go through the acidosis-hell until you lose consciousness. You'll need a induced coma for this (barbs+opioids), but that's just my opinion.

 

[Ruffian]

Soul even with all my attempts I never considered aspirin because I thought the effects sound dreadful as a way to go out. And salicylic products do make your skin gross sometimes, I just see it as slowly molting into a zombie like creature. I read the article and yeah, I would still say that. The tinnitus alone sounds horrifying - it is also a contribution to my being here. I thought about this all day - I see you gave up on it. But you know I love to add $.02. Sometimes I crush aspirin up and mix it with lemon juice and let it dry on my feet as an at home pedi. It works great to get that nasty dry feet stuff off. I don't remember it even stinging or being uncomfortable, but your thread made me think about it. It would probably take forever and be really uncomfortable.

 

[Soul]

Thank you, @chrijo! I think that's enough information for anyone who looks up this method.

@Ruffian, thank you too, especially for the foot tip. I wasn't actually thinking of aspirin, but of the two essential oils I mentioned up there. And it was quite theoretical curiosity, because they smell absolutely horrid.

In closing, though: Does everyone know that wintergreen lifesavers make sparks when you crunch them? Invest in a roll, invite someone you like into a dark closet and you'll see. Have fun!

 

[chrijo]

In closing, though: Does everyone know that wintergreen lifesavers make sparks when you crunch them? Invest in a roll, invite someone you like into a dark closet and you'll see. Have fun!

That made me laugh. Only good people go with other good people into dark closets and organize light shows with candies :-)

PS: I love the word "wintergreen"

 

[Ruffian]

Thank you, @chrijo! I think that's enough information for anyone who looks up this method.

@Ruffian, thank you too, especially for the foot tip. I wasn't actually thinking of aspirin, but of the two essential oils I mentioned up there. And it was quite theoretical curiosity, because they smell absolutely horrid.

In closing, though: Does everyone know that wintergreen lifesavers make sparks when you crunch them? Invest in a roll, invite someone you like into a dark closet and you'll see. Have fun!

Yas!!!

Yas!!!

I just realized I have a huge bag of wintergreens. They are so addictive

 

[sevenkarmas]

This thread is a few years old. My plan is charcoal in a tent, but I'm curious if anyone knows anything about this method? I am aware of the teenage athlete (Arielle, I think) who OD'd in 2006 or 2007.

 

[treetop.grazer]

I just bought 50ml of wintergreen oil to aid with a sport injury (or so I'm telling people), I'm applying it liberally each day ATM so no idea how much more I need to apply to feel any effects.