Kera

Kera

Experienced
Jul 16, 2023
260
Hello,

i have done a lot of research on propranolol and apparently propranolol alone or in combination can be very lethal in large overdoses. I currently have 24 g of propranolol and 5 g of amitriptyline, as well as domperidone, 2.5 g of diphenhydramine, and 2 mg of lorazepam, which I think should be enough, considering that others have died with much weaker doses. Does anyone have personal experience or other information that I may not be aware of? My biggest fear is how I will fare after the overdose and fear of failure.

LG
 
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Ceterum

Ceterum

Member
Aug 10, 2022
88
Hello,

i have done a lot of research on propranolol and apparently propranolol alone or in combination can be very lethal in large overdoses. I currently have 24 g of propranolol and 5 g of amitriptyline, as well as domperidone, 2.5 g of diphenhydramine, and 2 mg of lorazepam, which I think should be enough, considering that others have died with much weaker doses. Does anyone have personal experience or other information that I may not be aware of? My biggest fear is how I will fare after the overdose and fear of failure.

LG

beta-blockers can kill. iV administration would be recommended in this case (so you might have to switch to metoprolol, I'm not sure if there is iv propofol on the market) though, a high kalium level in your blood would help as well.
 
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Kera

Kera

Experienced
Jul 16, 2023
260
beta-blockers can kill. iV administration would be recommended in this case (so you might have to switch to metoprolol, I'm not sure if there is iv propofol on the market) though, a high kalium level in your blood would help as well.
Thanks for your tip. Intravenously is not an option for me.
According to my research, propranolol has the highest toxicity of any beta blocker currently on the market. That's why I chose propranolol. But according to statistics, people with metoprolol commit suicide more often than with propranolol and bisoprolol. Hmm 🤔
beta-blockers can kill. iV administration would be recommended in this case (so you might have to switch to metoprolol, I'm not sure if there is iv propofol on the market) though, a high kalium level in your blood would help as well.
Metoprolol as I.V.?
 
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Ceterum

Ceterum

Member
Aug 10, 2022
88
Thanks for your tip. Intravenously is not an option for me.
According to my research, propranolol has the highest toxicity of any beta blocker currently on the market. That's why I chose propranolol. But according to statistics, people with metoprolol commit suicide more often than with propranolol and bisoprolol. Hmm 🤔

Metoprolol as I.V.?

yes ... whatever goes in iv stays inside. But propanolol is also available iv I've seen.
 
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Kera

Kera

Experienced
Jul 16, 2023
260
yes ... whatever goes in iv stays inside. But propanolol is also available iv I've seen.
Hmm, how true! I'd rather have it intravenously too. I am worried that the high dose will cause vomiting. Although I take antimetic before. And then all the other meds 🙈 Thanks for your feedback :)
 
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A

Alpaca

Member
Sep 25, 2023
5
Which one do you think is best to go with propranolol, verapamil or ami?
I'm leaning towards the first one but because of amor and his girlfriend, I'm starting to think ami might be best.
 
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Kera

Kera

Experienced
Jul 16, 2023
260
Which one do you think is best to go with propranolol, verapamil or ami?
I'm leaning towards the first one but because of amor and his girlfriend, I'm starting to think ami might be best.
Definitely verapamil!! The calcium channel blocker verapamil enhances the effect of propranlol. Cupid didn't have verapamil.
And I don't get verapamil because I take beta blockers.
 
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A

Alpaca

Member
Sep 25, 2023
5
And using zolpidem instead of benzo isn't gonna make a big difference like it's still gonna knock me out right?
I can't get any benzo since I live in europe and don't have any illness or anything so my doc is sure as hell gonna say no.
 
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Kera

Kera

Experienced
Jul 16, 2023
260
And using zolpidem instead of benzo isn't gonna make a big difference like it's still gonna knock me out right?
I can't get any benzo since I live in europe and don't have any illness or anything so my doc is sure as hell gonna say no.
Yes, exactly!
 
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