M
Mizzmini45
Arcanist
- Dec 1, 2019
- 447
That's the problem. This is the only reason I regret not going to CRNA school nowI mean...where do you get this stuff? Like...that's the only thing...
That's the problem. This is the only reason I regret not going to CRNA school nowI mean...where do you get this stuff? Like...that's the only thing...
That's the problem. This is the only reason I regret not going to CRNA school now
This would be the perfect dream for me to successful do this method. I'm not no doc or nurse so I would screw up this method easily rather than get a peaceful ctb like that patient in the video. In a less screwed up world everyone would have access to this to ctb peacefully, and it would be free since it would be a human right. I wish I was gifted in the medical field in this screwed up world . I could do this so easily if I had the knowledge.
Hey, I was just wondering if you have actually actually seen what Propofol looks like first hand? It is an incredibly viscous solution. The formulation contains soybean oil, glycerol, egg lecithin and disodium edetate with sodium hydroxide. I use Propofol, its not like other injectables. I wonder if you have taken this into account when you think about the rate of infusion for instance? Typically when you are infusing Propofol a rate of infusion of 100 to 150 mcg/kg/min (6 to 9 mg/kg/h) for 3 to 5 minutes or a slow injection of 0.5 mg/kg over 3 to 5 minutes would be performed. Yet i noticed that you are talking about infusing 2000mg over 1.5 minutes. so 4000x more than usual. That is a significant difference not only in the amount of solute going through the line but also the amount that you are expecting to push through a vein. I think you need to give this a little more thought.What is propofol?
What is propofol?
Propofol, marketed as Diprivan among other names, is a short-acting medication that results in a decreased level of consciousness and lack of memory for events. Its uses include the starting and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. It is also used for status epilepticus if other medications have not worked. It is given by injection into a vein. Maximum effect takes about two minutes to occur and it typically lasts five to ten minutes. More info...
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Propofol - Wikipedia
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Propofol is a dangerous anesthetic. Only experienced anesthesiologists can use it. It is difficult to determine the dose of propofol. A large dose of propofol, which is rapidly injected, stops breathing. Michael Jackson's doctor did not know enough about propofol. He left the room after injecting propofol. He had to watch him. If he was observing, he might have noticed he wasn't breathing. Mechanical ventilation with an ambu was enough to save him. Abusing propofol is common by doctors, anesthetists, nurses and anesthesiologists. Unfortunately, many people even died in small doses under 100 mg. Probably with the bolus dose administered quickly. This property of propofol that makes it fatal. I think it's a peaceful way to CTB but it requires IV. You can find too many videos about vascular access on Youtube. It's not as hard as you think. I succeeded on my first try.
The important thing is a high dose that is injected in a short time. It causes apnea depending on the dose administered. Very high doses may also cause hypotension and cardiovascular collapse. We have a problem at this point. You have 10 seconds from the start of propofol injection to loss of consciousness. Of course with a quick injection. In slow injection, this period may be prolonged. How much propofol do you inject in 10 seconds? About 300 mg, with a green cannula and a large vein (bolus pushing). Perhaps more propofol with a wider cannula. 300 mg propofol injected quickly is sufficient to initiate an apnea. Probably this amount is enough for CTB for a 70 kg person but not guaranteed. So how do you do if you want more chance? It is possible with 3 vascular access. 3 cannula will be enough. A doctor CTB with this method. "Two needles were inserted into the dorsum of the left hand and one inserted into the right hand and each was attached to the intravenous fluid." So you can inject 2000 mg propofol in 5 minutes. This is a huge dose. Cardiovascular collapse will probably kill you without the need for an apnea. Please note that some of them CTB at doses lower than 100 mg. Propofol is usually sold as 5 x 200 ml vials (10 mg / 1 ml). Several anesthetists answered questions about propofol in Quora.
Could 400mg of propofol kill you? - Quora
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Is 1000 mg of propofol lethal if injected quickly? - Quora
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In order for propofol to cause apnea, it should be injected in high doses in a short time. So I had to make myself a gravity-fed mechanical injection system. A system that used three syringes (60 cc). Each syringe will have 665 mg of propofol. I tested the flow rate of the injection system. I inserted a blue cannula into a large vein on my left arm. The syringe contained 30 cc of sterile isotonic water. I used 1600 grams for gravity feed. 30 cc of water was finished in one minute. So flow rate was 0.5 ml per second with 1.6 kg. Also, let me remind that I use blue cannulae. I will increase the weight and do another test. I am planning to inject 2000 mg of propofol in 1.5 minutes.
As a result, although propofol is peaceful and reliable for CTB, the process is not easy. Still, it is worth the effort if you can find propofol somehow, but if you can find N, never mind the propofol.
Cases:
https://sanctioned-suicide.net/proxy.php?image=https%3A%2F%2Fcdn-images-journals.azureedge.net%2Fanesthesia-analgesia%2FSocialThumb.00000539-200904000-00000.CV.jpeg&hash=bfc8d745fd19085adef6becf3e905179&return_error=1
Death from Propofol: Accident, Suicide, or Murder? : Anesthesia & Analgesia
on was focused on a male registered nurse acquaintance, who had acquired propofol and other drugs in the course of his regular duties in a surgical intensive care unit. This is the first reported case of murder with propofol....
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Self-administrated propofol – a case report of a physician suicide
Fatal self-administrated propofol intoxication of a 29-years old anesthesiologist, found dead in his home, is reported. The toxicological screening, p…
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https://www.researchgate.net/publication/24213651_Death_from_Propofol_Accident_Suicide_or_Murder
Anestezi uzmanı anestezi ilacıyla intihar etti
İSTANBUL Üniversitesi Tıp Fakültesi'nde görevli anestezi doktoru Esra Yılmazlar (32), Fatih'teki evinde koluna anestezi ilacı enjekte ederek intihar etti
www.medimagazin.com.tr
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Üç doktorun ölüm nedeni yüksek doz
Erzurum Bölge Eğitim ve Araştırma Hastanesi'nde 15 ay içinde peş peşe ölen üç doktorun kanlarında anestezik ilaç kalıntısı çıktı.Doktorların uzun süre ayakta ve zinde kalabilmek için bu ilaçları kullandıkları belirtildi
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Thats why it has to be infused because you could only inject so much before falling asleep, so it would be impossible to inject enough to kill yourself in time before falling asleep.How do you inject it by yourself (the fill dosage befoe you fall asleep)?
Thats why it has to be infused because you could only inject so much before falling asleep, so it would be impossible to inject enough to kill yourself in time before falling asleep.
Hey, I was just wondering if you have actually actually seen what Propofol looks like first hand? It is an incredibly viscous solution. The formulation contains soybean oil, glycerol, egg lecithin and disodium edetate with sodium hydroxide. I use Propofol, its not like other injectables. I wonder if you have taken this into account when you think about the rate of infusion for instance? Typically when you are infusing Propofol a rate of infusion of 100 to 150 mcg/kg/min (6 to 9 mg/kg/h) for 3 to 5 minutes or a slow injection of 0.5 mg/kg over 3 to 5 minutes would be performed. Yet i noticed that you are talking about infusing 2000over 1.5 minutes. so 4000x more than usual. That is a significant difference not only in the amount of solute going through the line but also the amount that you are expecting to push through a vein. I think you need to give this a little more thought.
I'm thinking, why not put the whole dosage into a saline bag and let the drip run at full speed?
I mean a 500cc bag takes maybe around 30 mins for a 23g cannula. It may not be fast but the whole dose goes in anyway.
Any thoughts?
That is why I made my own injection system. This is a gravity-fed injection system. I can inject 2000 mg in 1 minute. 3 syringes work simultaneously. I will do it with 3 venous access. I tested my injection system with 0.9 saline.
I am not a doctor. This system was made with the common opinions of 4-5 anesthetists. They are all experts in their field. For about 2 months, I asked questions to anesthetists . The common idea of all of them propofol mortality depends on the administration rate and dose. 2000 mg propofol injected in 1 minute will most likely cause cardiovascular collapse.
View attachment 33161
How fatal is propofol depends on the speed of administration. In operations such as colonoscopy, propofol infusion provides a sedation that allows the patient to breathe on its own. In other words, even very large doses of propofol administered slowly are well tolerated by patients. They can breathe on their own. Propofol breaks down very quickly in the blood. So you have to inject large doses in a short time to start a fatal apnea or cardiovascular collapse.
Home made? Wow that's amazing.
My plan is just to chuck a ton of benzo, abit of fentanyl and alot of lignocaine into a 500cc bag and let it run, with the ingestion of propranolol and verapamil as backup.. If I had a similar device I guess it'd increase the reliability of my method.
I'm not sure if the 3 cannulae can withstand the pressure though.. Have you tried it out on maybe, say normal saline first?
That is true. It is Propofols profile that makes it a great anaesthetic and that is (i)rapid onset and distribution; (ii) rapid metabolism; (iii) very rapid recovery; (iv) limited cumulative effect that is useful for day-case surgery; (v) . The pharmacodynamic properties of propofol are dependent upon the therapeutic blood propofol concentrations. Steady-state propofol blood concentrations are generally proportional to infusion rates. So the "side effects" that you would normally see under these kind of circumstances would be for instance cardiorespiratory depression, which is likely to occur at higher blood concentrations which result from bolus dosing or rapid increases in infusion rates. I guess this is what we are looking for really isnt it? Sorry i didt realise at the beginning that your system was designed with 3 entries in mind, i thought that you were expecting to load all three syringes through one vein which is why i questioned it in the beginning. I think in theory absolutely it should work as it would be faster than putting it through an IV bag, although, given the right concentration in an IV bag and a couple of entry points, that should also do the trick, in fact I think this has already been used before successfully in a few suicides by Doctors.That is why I made my own injection system. This is a gravity-fed injection system. I can inject 2000 mg in 1 minute. 3 syringes work simultaneously. I will do it with 3 venous access. I tested my injection system with 0.9 saline.
I am not a doctor. This system was made with the common opinions of 4-5 anesthetists. They are all experts in their field. For about 2 months, I asked questions to anesthetists . The common idea of all of them propofol mortality depends on the administration rate and dose. 2000 mg propofol injected in 1 minute will most likely cause cardiovascular collapse.
View attachment 33161
How fatal is propofol depends on the speed of administration. In operations such as colonoscopy, propofol infusion provides a sedation that allows the patient to breathe on its own. In other words, even very large doses of propofol administered slowly are well tolerated by patients. They can breathe on their own. Propofol breaks down very quickly in the blood. So you have to inject large doses in a short time to start a fatal apnea or cardiovascular collapse.
Not sure whether you knew but, when Midazolam is used it actually reduces the dose of Propofol required for induction of anaesthesia.Lignocaine and F seems like a really good idea, man. Fentanyl closes consciousness, starts an apnea, and lignocaine stops the heart. I tested my system with sterile 0,9 water. It works well :). 1 cc per second is actually a pretty low speed. I tested it with 3 blue cannulae. There is no problem. I will also inject midazolam to increase the effect of propofol on CNS. It would be much more reliable if I could find liquid pentobarbital. It is not that easy to access in my country.
That is true. It is Propofols profile that makes it a great anaesthetic and that is (i)rapid onset and distribution; (ii) rapid metabolism; (iii) very rapid recovery; (iv) limited cumulative effect that is useful for day-case surgery; (v) . The pharmacodynamic properties of propofol are dependent upon the therapeutic blood propofol concentrations. Steady-state propofol blood concentrations are generally proportional to infusion rates. So the "side effects" that you would normally see under these kind of circumstances would be for instance cardiorespiratory depression, which is likely to occur at higher blood concentrations which result from bolus dosing or rapid increases in infusion rates. I guess this is what we are looking for really isnt it? Sorry i didt realise at the beginning that your system was designed with 3 entries in mind, i thought that you were expecting to load all three syringes through one vein which is why i questioned it in the beginning. I think in theory absolutely it should work as it would be faster than putting it through an IV bag, although, given the right concentration in an IV bag and a couple of entry points, that should also do the trick, in fact I think this has already been used before successfully in a few suicides by Doctors.
Not sure whether you knew but, when Midazolam is used it actually reduces the dose of Propofol required for induction of anaesthesia.
There are a number of reports out now of people mostly in the medical field who have committed suicide using Propofol, I guess because it easier to come by if you work in the industry. Its also quickly becoming a drug of abuse by Drs, nurses etc I wasnt thinking of using Propofol as my CTB method, actually until I saw your thread it just did not occur to me and here i am sitting at home with a few bottle of Propofol. I have a package of Sodium Nitrite making its way to me in a couple of days, however, sadly, thats not really how i want to CTB either. I feel like ive been backed into a bit of a corner because the method that i have always wanted to use and always planned to use to CTB which was with a gun, seems to be out of reach for me. I just cant seem to access a gun, so im left with having to make a decision about whether to wait until i find a gun or CTB with a different method. I have accees and the means to CTB a number of ways but i have decisions to make now.Yes you are right buddy and thanks for info. I read a case report of a doctor who killed himself with propofol. He used 3 IV access and 3 drip systems. I don't trust drip systems. I know all of propofol will be gone into my veins with injectors.
What is your method? Is it propofol? Im still looking for rocuronium. Propofol + rocuronium was drug combination of first euthanasia of Canada. It is OTC in my country lol, but still couldnt find it.
Yes you are right buddy and thanks for info. I read a case report of a doctor who killed himself with propofol. He used 3 IV access and 3 drip systems. I don't trust drip systems. I know all of propofol will be gone into my veins with injectors.
What is your method? Is it propofol? Im still looking for rocuronium. Propofol + rocuronium was drug combination of first euthanasia of Canada. It is OTC in my country lol, but still couldnt find it.
@laserfocus111 your in the US arent you? You cant get Rocuronium OTC can you?Drip system - are you worried that should the cardiac output drop, the drip may not be able to deliver the full dosage? My concern is whether if the lignocaine in my formulation causes seizures which may dislodge my drip line. Am hoping the midazolam will suppress that. An alternative method would be to split the dosage in a few drip lines but I hate the idea of ctb with so many lines attached.. it's just me.
Rocuronium OTC? That's impressive as well. I'd raise a few eyebrows if I were to acquire it.
Hi I'm somewhere in East Asia..@laserfocus111 your in the US arent you? You cant get Rocuronium OTC can you?
Yeh I thought as much, but @ThatsEnoughForMe said that he could get it OTC where he was didnt he? So are you also considering Propofol as a possible CTB?Hi I'm somewhere in East Asia..
I think it's hard to get it anywhere in most developed countries.
I mean the indication for roc is so specific :( Even healthcare workers not related to emergency dept/anesthesia/icu work will find it hard to obtain
Yeh I thought as much, but @ThatsEnoughForMe said that he could get it OTC where he was didnt he? So are you also considering Propofol as a possible CTB?
There are a number of reports out now of people mostly in the medical field who have committed suicide using Propofol, I guess because it easier to come by if you work in the industry. Its also quickly becoming a drug of abuse by Drs, nurses etc I wasnt thinking of using Propofol as my CTB method, actually until I saw your thread it just did not occur to me and here i am sitting at home with a few bottle of Propofol. I have a package of Sodium Nitrite making its way to me in a couple of days, however, sadly, thats not really how i want to CTB either. I feel like ive been backed into a bit of a corner because the method that i have always wanted to use and always planned to use to CTB which was with a gun, seems to be out of reach for me. I just cant seem to access a gun, so im left with having to make a decision about whether to wait until i find a gun or CTB with a different method. I have accees and the means to CTB a number of ways but i have decisions to make now.
Now getting back to the rocuronium. It is certainly not something that we (being me in New Zealand) would be able to access OTC (over the counter.) I would not imagine that you would be able to access rocuronium OTC in the US either, I not sure? Im sorry but where do you live that this drug is available over the counter? In most countries that im aware of rocuronium is used along with Thiopental in RSI (Rapid Sequence Induction). Drugs like rocuronium and succinylcholine would not be available OTC especially in light of what they can do and their use in procedures like RSI.
Yes that is right. Many doctors and nurses in my country committed suicide with propofol in the staff room or accidentally overdose while trying to get some sleep. Doctors and nurses work in terrible conditions in my country.
I have plans B and C. Drink sodium nitrite + 600 mg propofol bolus + 1400 mg infusion. With this plan, I will be unconscious until sodium nitrite kills me. My plan C is to add bupivacaine injection to my plan B.
I have a pharmacist connection. I bought the propofol from that person. If rocuronium comes to the pharmaceutical warehouse, I will buy it. An anesthesiologist said to me, propofol + rocuronium is an ideal combination of euthanasia. This combination was used in Canada's first euthanasia. Can succinylcholine do the same thing?
If you think it's not the right time for you, you can wait man. If you have access to drugs like propofol, CTB is always an open door for you. Sorry for my english im using google translate.
Drip system - are you worried that should the cardiac output drop, the drip may not be able to deliver the full dosage? My concern is whether if the lignocaine in my formulation causes seizures which may dislodge my drip line. Am hoping the midazolam will suppress that. An alternative method would be to split the dosage in a few drip lines but I hate the idea of ctb with so many lines attached.. it's just me.
Rocuronium OTC? That's impressive as well. I'd raise a few eyebrows if I were to acquire it.
Unlikely I'll have
Google translate is doing a fantastic job, don't worry. It looks like your plan just might work.
I'll probably never get propofol as I don't have your kind of contact. Midazolam is the closest thing I have.. Just iv 75mg of it or maybe I can get another 50mg maximum. It's not much I know, but I'll be hoping fentanyl (about 1mg) will have some synergistic effect. The real deal is my 9g of lignocaine I intend to use.
Not much difference between rocuronium and sux I believe. In my country I've seen docs use either depending on personal preference.
My mother was hospitalized because of bacterial pneumonia. I saw that the drip system infusion often stopped. Maybe something was wrong, I don't know. I just want a guarantee :)
Seizures are really the right point. I have no idea, is midazolam anti convulsive? If you can find a neuromuscular blocker, this problem will disappear. Dangerous enough even as a single agent.
Yes rocuronium OTC :). In fact, pharmacies don't sell it. Hospitals buy it from the manufacturer by tender. Sometimes it somehow goes to the pharmaceutical warehouse. Im planning to buy it when it comes to pharmaceutical warehouse. This is how I bought the propofol. Propofol and rocuronium OTC but etomidate, thiopental, F green recipe. I think the reason for this is that bureaucracy sucks in my country :)
Google does this job well, 70% successful. I fix the remaining 30% :) It is difficult for me to translate my language into English but I can understand what is wrong :)
Sorry for not being able to reach the medicines you want, my friend. I think you're right, the difference between succinylcholine and rocuronium may be the duration of action. The effect of succinylcholine begins in a very short time. I remember it used in intubation.
What country are you from? Google translate is doing a very good job. Im having no problems what so ever in understanding you. With regards to Propofol and Rocururonium as an ideal combination for euthanasia I would agree with you on that one. Yes Ive read several articles where it has been used in Canada for just that. With regards to Succinylcholine, my understanding is that either Succinylcholine or Rocuronium can be successfully used for onset of laryngeal paralysis. Succinylcholine generally takes about 45–60 seconds for the onset of laryngeal paralysis. When Rcuronium is dosed at the lower end of this range, it's onset of action is longer than the 45–60 seconds required for succinylcholine. So depending on where you practice medicine, some tend to favour one over the other, but as you can see, their pretty much the same in terms of their action and outcome.Yes that is right. Many doctors and nurses in my country committed suicide with propofol in the staff room or accidentally overdose while trying to get some sleep. Doctors and nurses work in terrible conditions in my country.
I have plans B and C. Drink sodium nitrite + 600 mg propofol bolus + 1400 mg infusion. With this plan, I will be unconscious until sodium nitrite kills me. My plan C is to add bupivacaine injection to my plan B.
I have a pharmacist connection. I bought the propofol from that person. If rocuronium comes to the pharmaceutical warehouse, I will buy it. An anesthesiologist said to me, propofol + rocuronium is an ideal combination of euthanasia. This combination was used in Canada's first euthanasia. Can succinylcholine do the same thing?
If you think it's not the right time for you, you can wait man. If you have access to drugs like propofol, CTB is always an open door for you. Sorry for my english im using google translate.
Propofol bolus? What would you suggest then in terms of a bolus?propofol bolus, plus drip, plus standard plastic bag will work. Put bag on, start drip (propofol in standard gravity is bag with normal saline), push bolus until you are unconscious. Out in 10 seconds and dead in 5 minutes or fewer.
What country are you from? Google translate is doing a very good job. Im having no problems what so ever in understanding you. With regards to Propofol and Rocururonium as an ideal combination for euthanasia I would agree with you on that one. Yes Ive read several articles where it has been used in Canada for just that. With regards to Succinylcholine, my understanding is that either Succinylcholine or Rocuronium can be successfully used for onset of laryngeal paralysis. Succinylcholine generally takes about 45–60 seconds for the onset of laryngeal paralysis. When Rcuronium is dosed at the lower end of this range, it's onset of action is longer than the 45–60 seconds required for succinylcholine. So depending on where you practice medicine, some tend to favour one over the other, but as you can see, their pretty much the same in terms of their action and outcome.
I always read with interest your plans as they are well thought out. Do you have medical knowledge or work in the medical field?
When i first read your Plan C which was to add Bupivacaine injection to your plan B i was at first quite confused. I was thinking why would someone be thinking about injecting a local anaesthetic into themselves as part of a CTB plan. Then I remembered a case that I had seen, admittedly it was a very long time ago, and when i say a long time ago, Im talking about 20 yrs ago. This 20 something yr old man come into the ED, he was very very sick, with a number of different symptoms including light headedness, visual disturbances, muscular twitching. Over time he started convulsing before going into a coma and eventually respiratory arrest. His diagnosis...... BUPIVACAINE-INDUCED CARDIOTOXICITY. Although rare, people can die of sudden cardiac death.I assume, this is what you were hoping to achieve in choosing to use Bupivacaine? Its just such an out there medication to choose, so I wonder why you chose to include it in your repetoire so to speak? Just interested?
Im familiar with drip etc what im asking is what would be your recomendation for a good bolus dose? Is there a mg dose you would say would be a good starting point? Obviously the idea being from what your saying, to push it through as fast as possible before succumbimg to unconsciousness.Like I said, bag on, immediately start drip, as soon as drip running, push a large bolus until unconscious. As for does, I would say as much and as fast as possible without blowing the cannula.
if unfamiliar with dosing, you likely will have extreme difficulty inserting a cannula (one handed and backwards from placing it in another person)
Adding SN isn't needed or Really fit, as the bolus would either do the job, or one would wake up and then have to deal with the SN and possibly aspiration into lungs, which would likely be extremely painful.