Does anyone know why in the Suicide Wiki it is suggested that people taking PPI regularly for acid stomach to stop PPI two weeks before taking SN. PPI reduces stomach acid for people taking it in regular basis, so it should help absorb the SN faster. What is the logic behind stopping it? And then taking Tagamet or Antacid half hour before SN. Doesn't make sense.
littlelady774
running on empty
- Dec 20, 2018
- 709
Acid reducers are no longer recommended for the SN method. Your stomach needs to be acidic for the chemical reaction of SN converting to Nitric oxide- which acts as a vasodilator
almostoutofhere
Living in the past
- Dec 27, 2022
- 163
littlelady774
running on empty
- Dec 20, 2018
- 709
That pretty much confirms I can't use SN then; I've been on a PPI since 2006 and without it go through even worse hell than I am already in...
I've also seen this. Still- isn't it in Stan's guide that the antacid prevents the acidity of the stomach turning the nitrite into nitrate? (Or, am I mistaken?) That also seems kind of important. Honestly, I don't know whether to leave it in the protocol or not.
littlelady774
running on empty
- Dec 20, 2018
- 709
You know, now I'm not so sure because that would make sense. Nitric oxide equals vasodilation which equals low blood pressure which equals faster time to unconsciousness. I would wait for the new edition of the ppeh to come out and see what it says about acid reducers.
Jarni
Love is a toothache in the heart. H.Heine
- Dec 12, 2020
- 383
And maybe the large dose of SN will overwhelm the inhibitory effect of a not big dose of antacids on Nitric Oxide...
Sodium nitrite: The “cure” for nitric oxide insufficiency
This process of “curing” food is a long practice that dates back thousands of years long before refrigeration or food safety regulations. Today food s…
But only the science could say exactly... Atm it is not clear..
lilin
Member
- Nov 22, 2020
- 92
littlelady774
running on empty
- Dec 20, 2018
- 709
I'm not sure. Early this year sometime I think.
Yeah I think you could do it either way. The stomach can't change all of it to nitrate. From my understanding, you want a fairly acidic environment to create gastric nitric oxide.And maybe the large dose of SN will overwhelm the inhibitory effect of a not big dose of antacids on Nitric Oxide...
Sodium nitrite: The “cure” for nitric oxide insufficiency
This process of “curing” food is a long practice that dates back thousands of years long before refrigeration or food safety regulations. Today food s…www.sciencedirect.com
But only the science could say exactly... Atm it is not clear..
Wikipedia says:
"Nitric oxide also acts on cardiac muscleto decrease contractility and heart rate."
Besides contributing to the low blood pressure, it may also help to lower the fast heart rate associated with methemoglobinemia.
Thanks
Thanks.
I always felt that when I took PPI the digestion of food was faster. Assuming that low acid facilitate passing the SN quicker thru the stomach to small intestine where it is actually absorbed into the blood stream. I believe this was the argument put forth by peaceful pill handbook initially. Now they're saying that is not the case? But I like the fact the acidity is good because it helps to become unconscious faster. Very interesting. But we need both faster absorption and faster unconsciousness to be successful and less painful.
Last edited:
littlelady774
running on empty
- Dec 20, 2018
- 709
Well now I'm confused cause I downloaded the latest ppeh and it said that acid reducers potentiate the nitrite so I'm not sure. I think you could SN with or without an acid reducer.
I looked it up, and nitrite + stomach acid will make nitrate, water, salt, and nitric oxide.
So I'm guessing if you take an antacid, you will absorb more nitrite than if you didn't take it.
If you don't take an antacid, you will absorb less because of the chemical reaction of your stomach acid turning it to nitrate, salt and nitric oxide.
Hope that makes sense. Anyone please correct me if I'm wrong
Thanks for the information. Which edition of the ppeh you saw this information? Is it Dec. 22? Do you have to subscribe to download it?
gomenasai
Student
- Sep 30, 2022
- 168
A member posted this excerpt the other day:
Seems like the antacid and betablockers aren't recommended (or necessary) anymore. The new protocol involves benzodiazepines and antiemetics. If anybody owns the latest PPEH edition, please confirm that this page really is the excerpt from the latest edition of PPEH. I couldn't find the latest edition online but the one from April does say that the antacid potentiates the nitrite. But allegedly they are no longer recommended in the most recent version.
Last edited:
littlelady774
running on empty
- Dec 20, 2018
- 709
Ah yes, I was looking at the April 2022 one. Does anybody have a download link to the latest version? I'd love to read it.
I had not seen this till now!
This is all So confusing to me now! Especially with all the research not drinking soda or juices to add to the acids in the stomach turning nitrite Into nitrate. I'm so confused!!
And have beta blockers been taken off as they are seen as just a luxury?
I really need some others input as I'm taking my SN either tonight or tomorrow .
I'm prepared both propanolol and Tagamet ! I'd planned to take both especially after fasting my stomach will be full of acid….
Things just don't add and the PPH still has a them listed. Please respond and let me know what your thoughts are cuz this is just as confusing as when to take the propanolol.
We need to see this new version where this change is made! Anyone access the new version of PPH that could post it for us (asap)! Thanks in advance
littlelady774
running on empty
- Dec 20, 2018
- 709
I would still take the anti acid and propranolol because thats what the logic says, but I don't know
It just doesn't make logic to me to not take Tagamet now after fasting as we've always been told no juice or soda and other drinks that would add to the stomach acids as this will make more nitrite turn into the nitrate which is what we don't want. We need the SN to absorb as much as possible as fast as possible. Im planning to take the Tagamet around 11pm and the propanolol I'll
Likely take half before amd half 200 mg with the first SN drink. Getting scared
as the reality of leaving this world and so many people I love behind . I can't face the pain it's going to cause my mother brother and my sister and the twins. They've kept me fighting but I can't go on anymore. Having them here 48 hours really made meRealize how much I'm gonna miss. Still
Can't believe I am Going to be capable of pulling this off , but the alternative is too
Much.
Honestly, I feel super confused on the antacid thing. Like lots of people have said- both options make sense. No antacid and maybe you'll pass out quicker due to the nitric oxide. Taking an antacid seems to reduce the chance of the nitrite turning into nitrate. (Which seems important!)
On top of this, I'm personally concerned because I don't have a gallbladder. I think most of my bile collects in my intestine now (probably not the stomach.) Most especially after fasting. I wonder if this would have any effect on the SN. I think bile is actually more alkaline. I just don't want it to be too alkaline so that if I take an antacid in addition, I don't pass out for ages. Still- I suppose if the reaction happens in the stomach, maybe it will be ok.
Really wish I'd studied biology/chemistry now. Don't suppose any clever folk out there have any ideas?
On top of this, I'm personally concerned because I don't have a gallbladder. I think most of my bile collects in my intestine now (probably not the stomach.) Most especially after fasting. I wonder if this would have any effect on the SN. I think bile is actually more alkaline. I just don't want it to be too alkaline so that if I take an antacid in addition, I don't pass out for ages. Still- I suppose if the reaction happens in the stomach, maybe it will be ok.
Really wish I'd studied biology/chemistry now. Don't suppose any clever folk out there have any ideas?
Shadowlord900
Seeker of Darkness
- Sep 29, 2022
- 918
I do wonder if the reason PPH are no longer recommend taking an antacid for SN is because I do know certain antacids like Gaviscon also form a protective layer above the contents of your stomach (well if you're fasting, I don't know how that would affect the protective layer). I wonder if that would somehow interfere with your body absorbing SN.
If that is the case, taking a PPI might be the better choice. It takes longer for the effects of PPI to kick in (you need to take at least 1 a day for 3-4 days in a row), but as far as I'm aware of, all it does shuts off the pumps in your stomach from pumping out acid, leading to a reduction of acid in your stomach.
If that is the case, taking a PPI might be the better choice. It takes longer for the effects of PPI to kick in (you need to take at least 1 a day for 3-4 days in a row), but as far as I'm aware of, all it does shuts off the pumps in your stomach from pumping out acid, leading to a reduction of acid in your stomach.
The Suicide Wiki says if you are taking PPI in regular basis for stomach acid, to stop it two weeks before SN and take Antacid half hour before. I don't understand why stop the PPI. Doesn't make sense. No one knows the actual reason. Ppeh didn't address the issue.
Similar threads
- sonatheri
- Suicide Discussion
Suicide Discussion
sonatheri
