Discussion Paracetamol vs. Ibuprofen — Which is better as a painkiller before SN?

[Zhoutongwei]

As the title suggests, I'm currently confused — which one is actually better?

Ibuprofen is known to have a stronger analgesic effect than paracetamol, and that's generally not disputed. However, according to SN-related statistics, far more people choose paracetamol as their painkiller before taking SN. Why is that?

 

[imOK]

You don't have to choose. You can take both in a combination. It's not harmful. Many cold medications etc. are basically nothing else than this combo.

 

[Zhoutongwei]

You don't have to choose. You can take both in a combination. It's not harmful. Many cold medications etc. are basically nothing else than this combo.

How should they be combined? Would 600mg of ibuprofen + 1000mg of paracetamolbe OK?
（That is to say, we use these two medications simultaneously at their maximum recommended doses.）

I remember there's a medication in the U.S. called Advil Dual Action, which combines both ingredients — each tablet contains 250mg of ibuprofen and 500mg of acetaminophen.

I'm considering taking two tablets of this medication one hour before the SN. It would be equivalent to taking 500mg of ibuprofen + 1000mg of acetaminophen at the same time.

Is that be a good approach?

 

[imOK]

Is that be a good approach?

I'm not a doctor (these often don't know either) and more importantly, not a pharmacist but I think it's probably safe to take the maximum therapeutic dosage. The problem with both these substances AFAIK is prolonged use which is not exactly something you need to worry about.

 

[Zhoutongwei]

I'm not a doctor (these often don't know either) and more importantly, not a pharmacist but I think it's probably safe to take the maximum therapeutic dosage. The problem with both these substances AFAIK is prolonged use which is not exactly something you need to worry about.

Thanks for your comment.

There's one concern I have about ibuprofen — I'm worried that using it might increase the risk of vomiting.
According to the information I found, taking ibuprofen can cause some gastrointestinal side effects, including nausea and vomiting. In other words, ibuprofen may significantly increase the risk of vomiting — maybe that's why most people choose paracetamol instead.

 

[imOK]

Try it, take some now. See if you feel anything. If you take something like SN that potentially makes you vomit I can't imagine something like Ibuprofen is going to make the big diference between vomiting and not vomiting. An antiemetic should counteract, at any rate.

 

[cowboypants]

Both are not mentioned in PPH book even now. I think it doesn't matter much. You can take both at the highest therepautic dose as another user mentioned.

 

[Zhoutongwei]

Both are not mentioned in PPH book even now. I think it doesn't matter much. You can take both at the highest therepautic dose as another user mentioned.

I also find this quite strange — why has PPEH never mentioned painkillers at all? Do they think the SN protocol doesn't require any pain relief?
Our SN protocol here is basically aligned with PPEH — the only difference is in the attitude toward painkillers. PPEH has never mentioned them, whereas our protocol has always recommended their use.
I also think we need painkillers. — I'm just confused . Maybe PPEH sees them as an 'unnecessary luxury,' which is why they haven't mentioned them.

 

[cowboypants]

I also find this quite strange — why has PPEH never mentioned painkillers at all? Do they think the SN protocol doesn't require any pain relief?
Our SN protocol here is basically aligned with PPEH — the only difference is in the attitude toward painkillers. PPEH has never mentioned them, whereas our protocol has always recommended their use.
I also think we need painkillers. — I'm just confused . Maybe PPEH sees them as an 'unnecessary luxury,' which is why they haven't mentioned them.

I think it might be unnecessary. If you have the meds, PPH has mentioned. Benzos will knock you out quickly(people have taken it before taking SN and many have coome back to tell they dosed off)

With paracetamol It can't be a luxury since they are OTC drugs. I plan to take it, though.

 

[Zhoutongwei]

I think it might be unnecessary. If you have the meds, PPH has mentioned. Benzos will knock you out quickly(people have taken it before taking SN and many have coome back to tell they dosed off)

With paracetamol It can't be a luxury since they are OTC drugs. I plan to take it, though.

You mentioned benzodiazepines — there's an issue with this class of drugs. If you take them, you'll fall asleep and lose consciousness more quickly, and in that state, you indeed won't feel any pain. But what if you vomit after falling asleep? How would you take the second glass of SN as a supplementary dose in that case?

 

[cowboypants]

You mentioned benzodiazepines — there's an issue with this class of drugs. If you take them, you'll fall asleep and lose consciousness more quickly, and in that state, you indeed won't feel any pain. But what if you vomit after falling asleep? How would you take the second glass of SN as a supplementary dose in that case?

Yeah i have the same questions you ask. And it's honestly scary. I think many of these can be answered only when we see videos personally, not one or two since there are many variations. Some might not have all of the meds or take little sn etc. This has to be scientifically done. PPH is the closest we have in that sense. Not to act like it's holy Bible lol

They recommend us to sit to lay back in a chair. I personally think that's the best one. Other option I feel is to lie on your sides.

We are taking many times the lethal dose, we will be a goner. I think that 10-15 minutes is enough for the lethal quantity to be absorbed. He does say to abort if you vomit and don't have additional glass

We can see the reports from here of people who have taken 1-3gm of SN. Even they have so many strong side effects. So it's almost a guarantee unless we are found quickly. My only gripe is without much videos to refer I feel little under confident about it like you say.

 

[kamyzyak]

You can also use ketorolac instead of ibuprofen if it's easily accessible in your country. It is a NSAID like ibuprofen, and 10-30 mg IM of keto is about equal to 10-12 mg IM of morphine. The oral bioavailability of ketorolac is 80-100%, so you can use it in pill form.

 

[tvgt]

I've seen the word SN but I still don't know what it means

As the title suggests, I'm currently confused — which one is actually better?

Ibuprofen is known to have a stronger analgesic effect than paracetamol, and that's generally not disputed. However, according to SN-related statistics, far more people choose paracetamol as their painkiller before taking SN. Why is that?