Help Oops. My medication is not working. What now.

[FormerlyFe(IV)]

I've been taking Lexapro for around three months and recently it started to wane off. Last two weeks have been the same shit.

Went to psychiatrist, asked for Buproprion. It was good for like, three days. And then back to rot. I now just heard that the medication has the most effect at the start. So basically, I'm fucked.

I can't wait around or have time to change meds. I should be waiting 28 days. Even if I changed now I was hoping to be good soon.

I got around 60 days left before I become evicted from my own home. I can't afford to wait to get better anymore.

I don't know what to do.
I'm lost.

 

[Praestat_Mori]

I got around 60 days left before I become evicted from my own home. I can't afford to wait to get better anymore.

I'm sorry this is additional inhumane pressure on you that will certainly not help to cure your "menthal health status". I don't no know anyting about you. But just reading this, it's clear what needs to be "cured" before there would even be a small chance to recover.

I'm really sorry I can't do more but saying this right now. I really hope you find a way to recover if this is what you really want.

 

[thornyrose]

There was a meta-analysis of meta-analyses published by Joanna Moncrieff and her colleagues in 2022 about how there's never been any proof that serotonin has anything to do with depression. Meaning that antidepressants are basically sugar pills with side effects. The major side effect is emotional blunting, which they're basically used for to get people to stop crying etc, disturbing others with their emotions. They don't really help very much. It makes very strong emotions bearable in the beginning, but the numbness caused by them starts to get to people over time. And the other treatments psychiatry has are even less helpful for the individual themselves. But don't tell about this to any psychiatrist, they'll be scared for their market if they know people know they've got nothing to actually help people with, and will take their fear/anger out on you with all the might of their legal powers. Just search information online and in books for confirmation of the facts I just shared with you.

Sometimes, the solution to getting better is to realise how uncaring so many other people are, and starting to look out for your own happiness. You're not going to get help from the mental health services, because they're not built to help you, they're there for society to deal with people who can't work a nine-to-five job. Basically, it's there to make them feel like it's their fault. When it's perfectly okay to be disabled, and there are self-employment options for example, but they take time to build unlike just getting a job. Please lean on any family/ relatives you may have as much as you need during this stressful time, and use the psychiatric system or any other social support system as much as you need to get the benefits that you need, just like they're using you to get their paychecks. You deserve support for simply being autistic, that can be disabling, but unfortunately countries don't grant benefits on that basis, so people end up being burned out, stressed out and depressed before getting them.

 

[LittleJem]

Hi, what dose of lex and what dose of wellbrutin?They can be taken together - are you taking them together? The research is that you get better efficacy with both of them.It is. really demoralising to get a result and for it to poop out - but you do need to test a medication for twelve weeks not just a few days to give it a proper chance. While they can work quickly (wellbrutin especially) they do not usually work for people necessarily until week 12. This is my medication combo at the moment. I am really fed up, It is better than not being on this combo though. I'm on 20 lex and 300 wellbrutin. If you haven 't had the doseages raised that should be your first port of call.

Also do check out my post on scopolamine. It really helped me straight away (but gave me bloodshot eyes so I had to stop it).
by the way if you buy DXM and use in the right amount together with the Wellbrutin you basically make your own auvelity 'Auvelity combines a N-methyl-d-aspartate (NMDA) receptor antagonist dextromethorphan (45 mg) with a norepinephrine-dopamine reuptake inhibitor bupropion (105 mg)


It all really sucks. But you do need to give a medication 12 weeks. And the lex/wellbrutin combo might be better than just wellbrutin.
This is the lexapro/wellbrutin combination research paper. The research shows it is worth waiting for the 12 weeks. People get results at different times:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778329/

 

[Hollowman]

Hi, what dose of lex and what dose of wellbrutin?They can be taken together - are you taking them together? The research is that you get better efficacy with both of them.It is. really demoralising to get a result and for it to poop out - but you do need to test a medication for twelve weeks not just a few days to give it a proper chance. While they can work quickly (wellbrutin especially) they do not usually work for people necessarily until week 12. This is my medication combo at the moment. I am really fed up, It is better than not being on this combo though. I'm on 20 lex and 300 wellbrutin. If you haven 't had the doseages raised that should be your first port of call.

Also do check out my post on scopolamine. It really helped me straight away (but gave me bloodshot eyes so I had to stop it).
by the way if you buy DXM and use in the right amount together with the Wellbrutin you basically make your own auvelity 'Auvelity combines a N-methyl-d-aspartate (NMDA) receptor antagonist dextromethorphan (45 mg) with a norepinephrine-dopamine reuptake inhibitor bupropion (105 mg)


It all really sucks. But you do need to give a medication 12 weeks. And the lex/wellbrutin combo might be better than just wellbrutin.
This is the lexapro/wellbrutin combination research paper. The research shows it is worth waiting for the 12 weeks. People get results at different times:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778329/

You actually trust the 'research'? It's all corrupt.

 

[suicidalloser]

it was my cue to die, of course taking it i the first place was just to get out of the ward so i can return to killing myself everyday

 

[LittleJem]

the scopolamine research is real: ain't nobody selling it for depression
and it works but has made my eyes sore

what else do we have other than the range of medication that has made it to sale. I have tried everything else.

 

[FormerlyFe(IV)]

Hi, what dose of lex and what dose of wellbrutin?They can be taken together - are you taking them together? The research is that you get better efficacy with both of them.It is. really demoralising to get a result and for it to poop out - but you do need to test a medication for twelve weeks not just a few days to give it a proper chance. While they can work quickly (wellbrutin especially) they do not usually work for people necessarily until week 12. This is my medication combo at the moment. I am really fed up, It is better than not being on this combo though. I'm on 20 lex and 300 wellbrutin. If you haven 't had the doseages raised that should be your first port of call.

Also do check out my post on scopolamine. It really helped me straight away (but gave me bloodshot eyes so I had to stop it).
by the way if you buy DXM and use in the right amount together with the Wellbrutin you basically make your own auvelity 'Auvelity combines a N-methyl-d-aspartate (NMDA) receptor antagonist dextromethorphan (45 mg) with a norepinephrine-dopamine reuptake inhibitor bupropion (105 mg)


It all really sucks. But you do need to give a medication 12 weeks. And the lex/wellbrutin combo might be better than just wellbrutin.
This is the lexapro/wellbrutin combination research paper. The research shows it is worth waiting for the 12 weeks. People get results at different times:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778329/

I really appreciate the in depth and well thought out reply. I'm happy to see other people more invested in drugs and their chemistry and published research here! I enjoy that aspect too haha

I don't think DXM is readily available in Brazil, or at least not with a bunch of acetominophen attached (ugh). I'm a bit scared/tentative but I'll read about scopolamine.

I also posted outside of the forum and I think the general consensus is to give it some more time maybe not 12 weeks, but I'll give it a month (what my psychiatrist advised) and probably up the dosages then. I'm still at the entry level dosages of 10mg Lexapro and 150mg Wellbutrin

Cheers mate

 

[LittleJem]

I really appreciate the in depth and well thought out reply. I'm happy to see other people more invested in drugs and their chemistry and published research here! I enjoy that aspect too haha

I don't think DXM is readily available in Brazil, or at least not with a bunch of acetominophen attached (ugh). I'm a bit scared/tentative but I'll read about scopolamine.

I also posted outside of the forum and I think the general consensus is to give it some more time maybe not 12 weeks, but I'll give it a month (what my psychiatrist advised) and probably up the dosages then. I'm still at the entry level dosages of 10mg Lexapro and 150mg Wellbutrin

Cheers mate

for severe depression 20 mg lexapro is better. I definitely found 300 mg wellbrutin better than 150 mg.

all the luck
that's wise - one month then up the dose

 

[FormerlyFe(IV)]

for severe depression 20 mg lexapro is better. I definitely found 300 mg wellbrutin better than 150 mg.

all the luck
that's wise - one month then up the dose

My personal issue with Lexapro is the tiredness. I started on 10mg and I asked for Buproprion instead of 20mg to my psychiatrist because I was so tired. If I didn't take an espresso in the morning, afternoon, and evening, I would basically just lay in bed all day. When my situation started getting worse a few weeks ago, not only did the antidepressant effect slowly wane (social anxiety slowly creeping in, more negative mood 'till I literally joined this forum) but also the coffee stopped being enough. Taking an espresso in the evening and then napping from 2 - 5PM sucks.

 

[HighFlight]

Hi, I hope you find the right combination of meds and dosage soon. As you know, this takes time and patience. Hang in there. I know its difficult as I'm going through the same games with my doctor.

For me, I'm on my 6th antidepressant and so far, they either don't work for me or the side effects are worse then the depression. I'm currently tapering off of Wellbutrin (200mg SR 2x daily), and am trying to decide what's next. They keep telling me that everything will be alright once you figured out the right drug(s) and dosage, but the time and effort it takes it's pushing me further away from recovery and hope.

But I know several people who have found the right combo and are living normal and happy lives. I pray you will be one of those people.