N - prolonged coma

[Advisor321]

Ok, let's say that I will drink 1.5 or 2 bottles of N.
I weight around 60kg.
Using antidepressants (NDRI and SARI). Benzo from time to time but very rarely. I'm not drinking any alcohol.

So is 6-7hours a good amount of time?
Because there are so much info that N needs 24hours window or even 48h for prolonged coma, but I really can't find a good evidence for that.
I really thought that N just takes about 1-3hours to be dead for average person, but now I'm really curious if really 24h window is obligatory.

 

[The_Flying_Fox]

I think the '24 hours window' is very exaggerated. The Dutch 'Centre of Expertise on Euthanasia', on its page for medical doctors who seek information/advice about assisted suicide, writes that 'by far most people die within 30 minutes', but that 'sometimes' the dying process can take longer, 'even 2 to 3 hours'. So they consider 2 or 3 hours as a very long dying process.

I have to add that on the same page they advice to give 15 grams of pentobarbital. You will be taking a little bit less, so for you the dying process might take a little bit longer, let's say 45 minutes instead of 30 minutes. But there's still no need for a 24 hour time window.

By the way, I had my N from D tested in February or March this year, by Energy Control International, the lab that is mentioned in the PPH. The results were that the sample contained 76 mg of pentobarbital per ml. So if you got your N also from D, and you drink 2 bottles, then you will consume even a little bit more than 15 grams. (This is also my own plan: to drink 2 bottles.)

 

[Ta555]

I think the '24 hours window' is very exaggerated. The Dutch 'Centre of Expertise on Euthanasia', on its page for medical doctors who seek information/advice about assisted suicide, writes that 'by far most people die within 30 minutes', but that 'sometimes' the dying process can take longer, 'even 2 to 3 hours'. So they consider 2 or 3 hours as a very long dying process.

I have to add that on the same page they advice to give 15 grams of pentobarbital. You will be taking a little bit less, so for you the dying process might take a little bit longer, let's say 45 minutes instead of 30 minutes. But there's still no need for a 24 hour time window.

By the way, I had my N from D tested in February or March this year, by Energy Control International, the lab that is mentioned in the PPH. The results were that the sample contained 76 mg of pentobarbital per ml. So if you got your N also from D, and you drink 2 bottles, then you will consume even a little bit more than 15 grams. (This is also my own plan: to drink 2 bottles.)

Going to throw this out there but the amount of N doesn't increase or decrease time to dying. N binds to receptors in the brain to make you stop breathing. It also inhibits glutamate which is an excitatory neurotrasmitter. You only have a finite number of receptors it can bind to so once all those receptors are taken all the other N floating around in your system isn't really doing anything. The higher amount is recommended for people with alcoholism and chronic anti-psychotic use because of N degradation in the liver, not because of time. I keep seeing people saying two bottles speeds up dying but I don't think that's true. Two bottles just ensures there's enough in your system to bind to all the receptors and not be degraded by liver enzymes, which again, only seems to be a concern for alcoholics and anti-psychotic users.
Also if you are heavier two bottles is advised because of the larger volume of blood in your body I would assume.
N travels through the blood and into the brain and binds to receptors. You don't have an infinite number of receptors and this is why the minimum lethal dose is so low (3g for the average person). Once the receptors are saturated, more N won't do anything to increase or speed up chances of death. Edit: just googled half life of pentobarbital and it says 4 hours. Which means half the drug is gone from your system in four hours.

The reason why alcohol and other substances can potentiate N is because there are several types of GABA receptors in your brain and N binds to one of them, the GABA A receptor. Alcohol also binds to GABA receptors but also inhibits excitatory receptors which helps sedation.

 

[Advisor321]

I think the '24 hours window' is very exaggerated. The Dutch 'Centre of Expertise on Euthanasia', on its page for medical doctors who seek information/advice about assisted suicide, writes that 'by far most people die within 30 minutes', but that 'sometimes' the dying process can take longer, 'even 2 to 3 hours'. So they consider 2 or 3 hours as a very long dying process.

Going to throw this out there but the amount of N doesn't increase or decrease time to dying. N binds to receptors in the brain to make you stop breathing. It also inhibits glutamate which is an excitatory neurotrasmitter. You only have a finite number of receptors it can bind to so once all those receptors are taken all the other N floating around in your system isn't really doing anything. The higher amount is recommended for people with alcoholism and chronic anti-psychotic use because of N degradation in the liver, not because of time.

Ok, but still there are histories here on SS, where people entered extended coma, and didn't die within few hours and their respiratory system was working for long long hours.

So the question need to be asked, were they alcoholics? Did they use psycho substances before? Or maybe their N was contaminated with something, not being pure enough.


It is really anxious for me who is considering N, that some people despite big amount of N taken survived. And I'm trying to understand why it did happen and what gone wrong

 

[Alex6216]

Ok, but still there are histories here on SS, where people entered extended coma, and didn't die within few hours and their respiratory system was working for long long hours.

So the question need to be asked, were they alcoholics? Did they use psycho substances before? Or maybe their N was contaminated with something, not being pure enough.


It is really anxious for me who is considering N, that some people despite big amount of N taken survived. And I'm trying to understand why it did happen and what gone wrong

Probably all three, I will say most are probably those who already experimented with alcohol. and drugs before which gave them a higher resistance or something.

 

[Advisor321]

Probably all three, I will say most are probably those who already experimented with alcohol. and drugs before which gave them a higher resistance or something.

Or maybe they used powder instead of liquid N.
Still it is a mystery for me the explanation of extended coma phase :(

 

[Alex6216]

Or maybe they used powder instead of liquid N.
Still it is a mystery for me the explanation of extended coma phase :(

Nah almost no one uses powdered N. It's more rare than gold.
A lot of SS users are alcoholics and some SS users also experiment with benzos and opioids

 

[Advisor321]

Nah almost no one uses powdered N. It's more rare than gold.
A lot of SS users are alcoholics and some SS users also experiment with benzos and opioids

I think powder N was available 3/4 years before in China, but it might have been contaminated

Maybe that was a cause of failed N taking

 

[Sobreviviente]

just googled half life of pentobarbital and it says 4 hours. Which means half the drug is gone from your system in four hours

Does it mean that if you was discovered 8 hours later after your death than it will be impossible to get know that the reason of your death was N?

 

[Advisor321]

Does it mean that if you was discovered 8 hours later after your death than it will be impossible to get know that the reason of your death was N?

I think it is possible because of metabolites of N that can still be in liver after ctb

 

[Ta555]

Ok, but still there are histories here on SS, where people entered extended coma, and didn't die within few hours and their respiratory system was working for long long hours.

So the question need to be asked, were they alcoholics? Did they use psycho substances before? Or maybe their N was contaminated with something, not being pure enough.


It is really anxious for me who is considering N, that some people despite big amount of N taken survived. And I'm trying to understand why it did happen and what gone wrong

Can you show me these posts? The only time I'm aware of this happening was from powdered N a long time ago. That N was from china and it was strongly suspected it wasn't pure N.
I've said this many times before around here, but if you're so scared of going into a coma then why not use a plastic bag around your head once you drink the N? Even if you go into a coma you'll just die quickly from suffocation without noticing. That's what some old people do who take N at home.

Does it mean that if you was discovered 8 hours later after your death than it will be impossible to get know that the reason of your death was N?

No, they will still find metabolites and things like that. They can still find out it was N.