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The reason why you can't take metoclopramide with quentapine is because they both act on dopamine receptors as dopamine antagonists, so the concern is that there will be excess dopamine in your system. But if you take them together, nothing terribly bad will happen and the effectiveness of meto will decrease. If it really bothers you then you can stop your Seroquel.Hi, I am on quetiapine which seems to not interact well with metoclopramide. ( For the sn method)
What is the next best option and is there any OTC options that are good enough?
Thanks
The thing is is that my doctor might not prescribe it because they will know that I am on quetiapine. Is there another option?
sanctioned-suicide.net
Other way around: they are both dopamine antagonists, so they reduce (block) dopamine activity. They can both cause Parkinson's like symptoms when taken alone. Combining them increases the risk and can lead to movement disorders like tardive dyskinesia and in severe cases neuroleptic malignant syndrome:
www.singlecare.com
I am a bit sceptical about that information.Is it Quetiapine- 245 nM? Stan's guide suggests no need to take meto if you are on one of the listed medications as they already act as an antiemetic.
Stan's Guide to SN.
Sodium Nitrite (SN) Method Introduction This document has been designed to give a full understanding of SN, what it is, how it works and how to use it. It will use the most simplest way of delivering this information as many members do not have English as their first language. Therefore using...
How do I know if it's 245 nm?Is it Quetiapine- 245 nM? Stan's guide suggests no need to take meto if you are on one of the listed medications as they already act as an antiemetic.
Stan's Guide to SN.
Sodium Nitrite (SN) Method Introduction This document has been designed to give a full understanding of SN, what it is, how it works and how to use it. It will use the most simplest way of delivering this information as many members do not have English as their first language. Therefore using...
Domperidone may actually be better than meto for some people. It's a shame that it's not for sale in the US.
Look up D2 antagonists. The higher the affinity the better. You might not need.
The reason why it says that is because combining them increases the dopamine antagonism. But it's notable that these symptoms are additive and not multiplicative. The warning is mainly to prevent careless doctors from therapeutic duplication and accidentally overdosing their patients on dopamine antagonists.
That's a good question. It works well in theory, but idk how good in reality.
I bet the reason for this is because it also acts on 5HT2A and 5HT1A receptors, which have nothing to do with antiemetics and affect your mood. A high enough dose that would cause good enough antiemetic properties would also cause unwanted side effects. Which is my guess for why metoclopramide is used, because it targets more specifically for D2.
