Methemoglobinemia SN

[Terminally ill]

I am trying to research as much as I can about SN and I found the following article about methemoglobinemia : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1071541/. What worries me is the following: "N-Acetylcysteine, cimetidine, and ketoconazole are experimental therapies in the treatment of methemoglobinemia that have shown some promising results.20,21,22 Exchange transfusion is reserved for patients in whom methylene blue therapy is ineffective."

We are taking cimetidine or famotidine or ranitidine as an antacid to INCREASE the chances of succes with SN but here it is said that cimetidine is actually considered to be a recovery therapy for methemoglobinemia. What am I missing here?

 

[S1mpleme]

Skip meds. My method:
1 bottle of vodka couple hours before SN;
Up to 25g of SN (not sure how much of this shit I can drink).

 

[Terminally ill]

Well thats not very well planned and drinking is not recommended with SN from what I have been reading. Maybe try and look at this as this is the most important decision in your life kind of way and take care.

 

[S1mpleme]

I very recommend myself to drink before SN.

 

[Ἡγησίας]

You shouldn't be worried, there is no quantity of antacid able to reverse the methemoglobinemia caused by a massive SN intoxication.

 

[GoodPersonEffed]

Here's the link to the article that addressed cimetidine in the OP, reference 21:

The use of cimetidine to reduce dapsone-dependent methaemoglobinaemia in dermatitis herpetiformis patients.

1. We have attempted to reduce dapsone-dependent methaemoglobinaemia formation in six dermatitis herpetiformis patients stabilised on dapsone by the co-administration of cimetidine. 2. In comparison with control, i.e. dapsone alone, methaemoglobinaemia ...

www.ncbi.nlm.nih.gov

Cimetidine was administered over several days. I would tend to agree with @Mainlænder that the regimen dose of cimetidine would likely not have much if any impact.

I also respect that @Terminally ill is doing their due diligence, and appreciate bringing research to the group.

 

[jgm63]

I very recommend myself to drink before SN.

I would recommend you don't mix alcohol and SN.
There's a big risk of failing.....
Please take a read of :

Spoiler: post-570165

https://sanctioned-suicide.net/thre...ces-information-google-docs.29900/post-570165

Please also read :

Spoiler: post-375402

https://sanctioned-suicide.net/threads/taking-sn-tonight.19977/post-375402

Please follow Stan's guide as closely as you can.
If you need any help / input, etc, just ask.....