PurpleParadigm
The glow is an illusion
- Mar 22, 2023
- 201
Hi folks, I have stumbled upon this paper which thankfully was available for free on pubmed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520478/
For context, I am experiencing a very sharp mental decline, with memory loss and inability to learn new things being the core element of it.
Here are some key point that stood out for me from the summary:
I hope this can help some folks at least validate their experiences.
For context, I am experiencing a very sharp mental decline, with memory loss and inability to learn new things being the core element of it.
Here are some key point that stood out for me from the summary:
- Prevalence and Persistence of Cognitive Disorders in Depression
- Cognitive disorders frequently reported in depression include deficits in attention, executive functions, memory, and processing speed
- Cognitive problems often persist even during remission of depressive symptoms, with prevalence rates of up to 94% during depressive episodes and up to 44% during remissions
- Pseudodementia and Cognitive Impairments in Major Depression
- Some cases of major depression are characterized by prominent cognitive impairments, leading to the controversial condition known as pseudodementia
- Pseudodementia (mental decline caused by depression) has not been integrated into current dementia classification systems
- Depression is associated with a twofold increased risk of developing dementia, according to a meta-analysis study
- Cognitive Disorders as Core Features of Depression
- Cognitive disorders should be viewed as a core feature of depression, separate from being merely secondary to it, and a cause of functional impairment
- Cognitive symptoms in depression should be recognized as an important target for treatment
- Reversible and irreversible cognitive deficits can coexist in depressed patients
- Currently available antidepressant drugs have not demonstrated efficacy in treating cognitive disorders
- Cognitive Disorders across Different Mental Disorders
- Cognitive disorders are now recognized across different mental disorders, including ADHD, schizophrenia, and major depressive disorder (MDD)
- Cognitive function should be a critical target for therapy in MDD, as it significantly impacts mental health-related quality of life
- It doesn't always affect treatment decisions in practice
I hope this can help some folks at least validate their experiences.