Much has been said in praise of MDMA-assisted therapy for PTSD and treatment-resistant depression — and often with good reason. In some cases, it reopens mishealed wounds, softens trauma, and restores a sense of humanity.
But in others — quieter, less celebrated — it can become the prelude to a definitive departure.
I'm referring to individuals who have lived for years with chronic suicidal ideation, not out of hope, but because of fear, hesitation, or a sense of obligation toward others.
MDMA, at certain doses, doesn't eliminate pain — it eliminates fear.
And once fear is gone, nothing remains to stop the act.
Reports and anecdotal evidence suggest:
100–125 mg: standard therapeutic effect — emotional opening, relaxation, possible cathartic release.
150–180 mg: in vulnerable individuals, existential anxiety dissolves; calm euphoria may emerge. Suicidal thoughts may appear without emotional charge.
200–250 mg or more: complete erasure of the survival instinct. The person may enter a state of cosmic fusion, ego dissolution, and full acceptance of non-being.
> "I felt complete. I could go. It was time."
At that point, the shift from ideation to determined suicide can happen quietly, peacefully, and without distress.
No panic. No despair.
Only clarity and surrender.
This is not overdose. It's not abuse. It's a calmly prepared exit, made finally possible.
Those administering MDMA in clinical trials must understand this.
They must distinguish those seeking healing from those who are merely waiting for the neurochemical permission to leave.
Open question to the forum:
Have you encountered, read, or experienced anything similar?
Do you believe this possibility is taken seriously enough in therapeutic contexts?
Let's speak without filters. Truth, like death, should not be censored.
But in others — quieter, less celebrated — it can become the prelude to a definitive departure.
I'm referring to individuals who have lived for years with chronic suicidal ideation, not out of hope, but because of fear, hesitation, or a sense of obligation toward others.
MDMA, at certain doses, doesn't eliminate pain — it eliminates fear.
And once fear is gone, nothing remains to stop the act.
Reports and anecdotal evidence suggest:
100–125 mg: standard therapeutic effect — emotional opening, relaxation, possible cathartic release.
150–180 mg: in vulnerable individuals, existential anxiety dissolves; calm euphoria may emerge. Suicidal thoughts may appear without emotional charge.
200–250 mg or more: complete erasure of the survival instinct. The person may enter a state of cosmic fusion, ego dissolution, and full acceptance of non-being.
> "I felt complete. I could go. It was time."
At that point, the shift from ideation to determined suicide can happen quietly, peacefully, and without distress.
No panic. No despair.
Only clarity and surrender.
This is not overdose. It's not abuse. It's a calmly prepared exit, made finally possible.
Those administering MDMA in clinical trials must understand this.
They must distinguish those seeking healing from those who are merely waiting for the neurochemical permission to leave.
Open question to the forum:
Have you encountered, read, or experienced anything similar?
Do you believe this possibility is taken seriously enough in therapeutic contexts?
Let's speak without filters. Truth, like death, should not be censored.
