"In ethylene glycol poisoning, oxalic acid is formed through aldehyde metabolites, and is generally assumed to be the cause of the renal failure associated with ethylene glycol poisoning [13]. The CNS and cardiopulmonary effects are speculated to be due to the aldehyde metabolites. The present case also suggests that the direct toxicity of oxalic acid involves renal failure without significant cardiopulmonary or CNS manifestations."
It is interesting because "Ethylene glycol is the ingredient that makes antifreeze tasty. Though colorless and odorless, the syrupy alcohol derivative—which is excellent at lowering the freezing points of vital engine fluids—has a sweet taste that jibes well with soda, juice, and other sugary beverages. As many concerned pet owners and parents are well aware, dogs, cats, and kids are prone to lap up puddles of antifreeze left on garage floors. Every year, 90,000 animals and 4,000 children ingest the toxic liquid; if not treated immediately, the consequences of the poisoning can include renal or cardiovascular failure, brain damage, and death."
A New Jersey woman has pleaded not guilty to murdering her brother-in-law with an antifreeze-spiked drink. According to prosecutors, Maryann Neabor's...
slate.com