• ⚠️ UK Access Block Notice: Beginning July 1, 2025, this site will no longer be accessible from the United Kingdom. This is a voluntary decision made by the site's administrators. We were not forced or ordered to implement this block. If you're located in the UK, we recommend using a VPN to maintain access.

CesiumBullet

CesiumBullet

Member
May 7, 2025
26
Is it possible to ever be entirely cured? Or does it just keep coming back?

I've been in and out of depression since I was 10. I'm 25 now and it just feels worse than ever. I've done therapy. I've taken meds. I have a great support system. But I always wind up here again. Right when I think my depression is gone, it hits harder than last time. Is the light at the end of the tunnel an illusion? It just seems to get further away right when I think I have it.
 
  • Hugs
Reactions: usernamesarehard, Hero Remeer and Electra
clavicle

clavicle

Member
May 8, 2025
21
i think your life circumstances would have to change drastically, like moving, getting a new job, new friends ect
 
  • Like
Reactions: Hero Remeer
Britney Spears

Britney Spears

toxic
Jan 4, 2025
477
It depends on what's causing it. If it's due to something chronic and incurable, it's very complicated. And on top of that, we add anxiety, is worse. If the root cause of the damage has no cure or solution, there is no remedy
 
  • Like
Reactions: Hero Remeer, broken_stoic and Hollowman
dewdrop

dewdrop

always freaked out
Apr 20, 2025
25
For some people, but it's not always just a matter of "trying hard enough" or "self improvement" like the common narrative that's pushed to guilt trip you. You can try exercise, therapy, countless medications, and everything else they say to do, and still be miserable, whereas someone else tries one single SSRI or some talk therapy and they go into remission just like that. I think it really depends on the person, their physiology, and the root cause of their mental illness. A lot of people have depression due to life circumstances, and some people are just genetically predisposed. This isn't to say that one group is necessarily easier to treat than the other, but that depression is a blanket label for a broad group of symptoms, and people with the same diagnosis can have all kinds of different causes, and different reactions to the same standard treatment protocols.

I am in a similar boat as you, having tried all of the recourses at my disposal, and it's so incredibly frustrating. I'm really sorry. I recently took a genetic test through my psychiatrist that will tell me which psychiatric medications I'm more likely to metabolize well based off of genetic markers. It is just a general guide to follow, and I'm still waiting on my results. Maybe this could be an option to consider if you are really struggling with where to go next as far as meds go, or have been experiencing a lot of side effects on them.
 
Last edited:
  • Like
Reactions: Britney Spears
CesiumBullet

CesiumBullet

Member
May 7, 2025
26
I recently took a genetic test through my psychiatrist that will tell me which psychiatric medications I'm more likely to metabolize well. It is just a general guide to follow, and I'm still waiting on my results. Maybe this could be an option to consider if you are really struggling with where to go next as far as meds go, or have been experiencing a lot of side effects on them.
What's the genetic test called? I think it might be worth a shot for me...
 
dewdrop

dewdrop

always freaked out
Apr 20, 2025
25
What's the genetic test called? I think it might be worth a shot for me...
I did mine through GeneSight. It's called a pharmacogenomic test. I hope eventually we will both find something that helps! Good luck. :)
 
  • Like
Reactions: CesiumBullet
Electra

Electra

The relief of giving in to destruction
Jul 1, 2024
584
I sometimes feel like having an innate personality that leans towards melancholism + life experiences could potentially cause depression with no cure, because it is more "endogenic".
 
A

AnxiousLlama

UKbro
Apr 29, 2024
59
lots of solutions, but they tend to be temporary.
 
  • Like
Reactions: usernamesarehard
Kimlett

Kimlett

Student
Jan 7, 2024
136
For some people, but it's not always just a matter of "trying hard enough" or "self improvement" like the common narrative that's pushed to guilt trip you
Well said.

Some people get rid of it forever, some people never do. Pure luck.
 
  • Like
Reactions: usernamesarehard
broken_stoic

broken_stoic

Wander till you find your place
Aug 21, 2024
138
It really depends on the person and cause as others have said. Some people get on the right meds or get the right therapy and they're golden. For alot of people with long-term chronic depression it's always going to be a struggle, but it can often get better so not every day is a battle. For myself therapists have told me with the level of depression/anxiety/trauma I have it will never go away completely, and making it go away isn't the goal. The goal is to improve symptoms significantly and learn tools to cope when symptoms become problematic. The eventual goal is you get to a good enough place that you are effectively on "maintenance." In other words you are more or less "ok" but still still need boosters to keep you in that state.
 
calloftheabyss

calloftheabyss

Member
Aug 30, 2023
18
That's a two-part answer. Depression usually comes from a mix of environmental factors (like life stress or trauma) and biological factors (like brain chemistry or physical health issues). Whether your specific depression is curable depends on which of those factors are at play—and how much they can be changed.

If it's mostly environmental (such as world events or personal stress are dragging you down) then there's often room for change through therapy (CBT would be perfect for this), mindset shifts, or lifestyle adjustments. It's not easy, but it's possible.

If it's more biological (Such as your brain has trouble regulating things like dopamine or serotonin) it might take more trial and error. Medications can help, and sometimes doctors discover other underlying issues, like gut health problems, that affect mood (Semi-related fun fact: a lot of your "Mood" chemicals are produced in the gut, so gastrointestinal issues can have profound affects on mental health).
 
  • Informative
Reactions: monetpompo
usernamesarehard

usernamesarehard

Life sucks and then you die
Dec 22, 2021
157
I'm pretty late to the party and everyone's already said what I would've said. But, yeah if your depression is a biological thing and not an environmental thing then I think it's just luck whether or not it truely goes away.

I'm on meds and it didn't cure my depression. They help immensely. Before I started them I couldn't work on things at home. I could only sleep. I'd sleep the entire day away, wake up an hour before work, rush to take care of the animals and pack lunch and head to work. Now I wake up at a reasonable time. I have energy and that helps a lot with doing things I'm both motivated and not motivated to do.

But I'm still here. I'm still depressed. I'm depressed because my boyfriend dumped me, but I was still depressed and suicidal when I was with him. Us getting back together wouldn't change the fact that I'm depressed. I'd just be depressed for no reason again.

He also suffered from being depressed and suicidal when he was younger. As far as I'm aware he wasn't suicidal while we were together, but he still had moments where he was depressed.

Personally I don't think this will ever go away for me. I'll be able to forget about it for periods of time. But I'll always be stuck with it. It'll show up again at some point.
 
leloyon

leloyon

I'll see you in the Wired.
Feb 4, 2023
1,410
Depends. I have a genetic predisposition to depression, and I don't really know what life is like without it, so I doubt I will ever be cured.
 
karakoltriste

karakoltriste

I hate psychiatry
Apr 30, 2025
242
Depression is not a illness (not as biomedical modernism wants us to believe) but yes
 

Similar threads

catlover20
Replies
29
Views
961
Recovery
FoxSauce
FoxSauce
W
Replies
1
Views
276
Suicide Discussion
locked*n*loaded
locked*n*loaded
PaperStar
Replies
13
Views
665
Suicide Discussion
DoMore
D
either/or
Venting New here
Replies
4
Views
386
Recovery
a-fond-farewell
a-fond-farewell