I want an easy, painless, quick, and effective method to CTB

[milly]

I live in a shitty country :) Propofol is not on the police-controlled list of narcotics. That's why it's on the OTC drugs list. It's still bs but it is. You can't buy Xanax but propofol free :) There is no propofol in pharmacies. I've asked a few pharmacies to check if it's in their drugstore. Luckily I found it somewhere. Some vets also buy propofol from there.

Nice avatar,.. Ms @DeadHorse

 

[Sunset Limited]

Just fyi your english is excellent, google translate is working perfectly.

This is true. I've been a member here since 2019. Google translate was not that successful in 2019. I know English at intermediate level. So I have a hard time forming sentences and I know very few words. But I can see what's wrong with the English text I'm reading.

I write my posts in my language. I am checking the english translation of google translate. I correct errors if any. So in this way. Every year since 2019 I have had to fix it less and less. It really works very well now :)

Nice avatar,.. Ms @DeadHorse

Hahaha it is my dream method. Thank you

 

[nihilism44]

I don't know :) I guess Customs will never approve of it :) Few people will prefer it because it requires an IV. Propofol is a good alternative to N.

This is from my personal experience in veterinary medicine, not human, but propofol is short-acting from my understanding. How could that alone be useful for ctb? Do you have to mix it with something else? Genuine question, I'm intrigued. Especially because propofol is not a controlled drug in the US.

 

[Sunset Limited]

This is from my personal experience in veterinary medicine, not human, but propofol is short-acting from my understanding. How could that alone be useful for ctb? Do you have to mix it with something else? Genuine question, I'm intrigued. Especially because propofol is not a controlled drug in the US.

I'll do it by infusion. I will put 4000mg/400ml propofol in a serum bag. I will have IV access on my left arm and the dorsum of my left hand. I'll connect them to the IV bag and start the infusion. The flow rate I will get from the gravity feed will be 18ml/min. So 180mg/minute of propofol. After about 2 minutes, my breathing will stop. I will be hypotensive after 4-5 minutes. I'm expecting a circulatory collapse in 7 minutes. Propofol doesn't just stop breathing. It causes arterial vasodilation and profound hypotension depending on the dose with its negative inotropic effect. I'll probably die in 10 minutes.

Propofol is the most dangerous IV anesthetic. Nurses and doctors have died with doses of just 50-100mg. Even a 200mg bolus has the potential to kill you. The LD50 of propofol is close to 1/10 in humans compared to animals. Anesthesia induction dose is around 2mg/kg.

 

[Ta555]

I'll do it by infusion. I will put 4000mg/400ml propofol in a serum bag. I will have IV access on my left arm and the dorsum of my left hand. I'll connect them to the IV bag and start the infusion. The flow rate I will get from the gravity feed will be 18ml/min. So 180mg/minute of propofol. After about 2 minutes, my breathing will stop. I will be hypotensive after 4-5 minutes. I'm expecting a circulatory collapse in 7 minutes. Propofol doesn't just stop breathing. It causes arterial vasodilation and profound hypotension depending on the dose with its negative inotropic effect. I'll probably die in 10 minutes.

Propofol is the most dangerous IV anesthetic. Nurses and doctors have died with doses of just 50-100mg. Even a 200mg bolus has the potential to kill you. The LD50 of propofol is close to 1/10 in humans compared to animals. Anesthesia induction dose is around 2mg/kg.

I'm not sure what you mean by most dangerous...it's actually safer than benzo/fentanyl combination. I've been reading studies on it because I'm having a minor procedure that requires anesthetic and I don't want benzo again so I'm going with propofol. The death rate with propofol was like 2 per 100,000 and benzo/fentanyl was about 11 per 100,000.
But if you mean dangerous in overdose then yeah it has much more cardiac and respiratory effects than other anesthetics.

 

[Sunset Limited]

I'm not sure what you mean by most dangerous...it's actually safer than benzo/fentanyl combination. I've been reading studies on it because I'm having a minor procedure that requires anesthetic and I don't want benzo again so I'm going with propofol. The death rate with propofol was like 2 per 100,000 and benzo/fentanyl was about 11 per 100,000.
But if you mean dangerous in overdose then yeah it has much more cardiac and respiratory effects than other anesthetics.

My knowledge of midazolam is limited. Propofol is the most dangerous of the anesthetics used for induction of anesthesia such as etomidate, thiopental sodium, and ketamine. Even the standard induction dose stops breathing. I have never read about the mechanism of action of midazolam.

I assume you have a procedural sedation. Is this an endoscopy or a colonoscopy? I don't know the criteria for the statistics you mention. What I do know is anesthesia is easy, sedation is difficult. From what I have read, patient satisfaction is higher with propofol in procedural sedation than with midazolam. I think the therapeutic dose required for depth of sedation with midazolam is very precise. This may be what makes it deadly. I think propofol is a good choice. I don't know if the statistics include cases of sepsis. Since propofol is an oil emulsion, it carries the risk of sepsis. I've read news of people dying from sepsis due to propofol in my country.

 

[Ta555]

My knowledge of midazolam is limited. Propofol is the most dangerous of the anesthetics used for induction of anesthesia such as etomidate, thiopental sodium, and ketamine. Even the standard induction dose stops breathing. I have never read about the mechanism of action of midazolam.

I assume you have a procedural sedation. Is this an endoscopy or a colonoscopy? I don't know the criteria for the statistics you mention. What I do know is anesthesia is easy, sedation is difficult. From what I have read, patient satisfaction is higher with propofol in procedural sedation than with midazolam. I think the therapeutic dose required for depth of sedation with midazolam is very precise. This may be what makes it deadly. I think propofol is a good choice. I don't know if the statistics include cases of sepsis. Since propofol is an oil emulsion, it carries the risk of sepsis. I've read news of people dying from sepsis due to propofol in my country.

Endoscopy yes. For endoscopies it seems to have a higher safety profile. I don't know the difference between procedural and general Anesthesia but from what I've read people say they feel better with propofol.

 

[Sunset Limited]

Endoscopy yes. For endoscopies it seems to have a higher safety profile. I don't know the difference between procedural and general Anesthesia but from what I've read people say they feel better with propofol.

Propofol is a good choice, my friend. Patient satisfaction is very high. In general anesthesia, consciousness is completely closed. Sedation is aimed at amnesia. Actually you are there, you obey the commands but you always forget. Propofol is very successful in this regard. Not only does it offer better sedation, a better awakening and no nausea. You also have the conscious option of having a local anesthetic sprayed down your throat. This is generally practiced in poor countries. I don't know if it's uncomfortable or not. I wish you well.

 

[GentleJerk]

SN and N are the obvious candidates.

 

[Johnjohn1]

How quickly do most people pass away from two bottles of vet N?

 

[ddd1234]

How quickly do most people pass away from two bottles of vet N?

Hard to say, some people say that it's only couple of minutes.

 

[Smart No More]

How quickly do most people pass away from two bottles of vet N?

It varies quite a bit. Some people can take hours. Some minutes. Most people are unconscious very quickly either way.

Propofol is a good choice, my friend. Patient satisfaction is very high. In general anesthesia, consciousness is completely closed. Sedation is aimed at amnesia. Actually you are there, you obey the commands but you always forget. Propofol is very successful in this regard. Not only does it offer better sedation, a better awakening and no nausea. You also have the conscious option of having a local anesthetic sprayed down your throat. This is generally practiced in poor countries. I don't know if it's uncomfortable or not. I wish you well.

I've had endoscopy with midazolam. I have never forgotten the experience. I've also had a midazolam and fentanyl combination. Each time they used local anaesthetic spray in the throat alongside it. I've remembered each procedure. I'm not sure if propofol is an option where I am.

@Ta555 out of interest, what stops you wanting to go with the benzo, did you have a bad experience with it?

 

[Sunset Limited]

It varies quite a bit. Some people can take hours. Some minutes. Most people are unconscious very quickly either way.

I've had endoscopy with midazolam. I have never forgotten the experience. I've also had a midazolam and fentanyl combination. Each time they used local anaesthetic spray in the throat alongside it. I've remembered each procedure. I'm not sure if propofol is an option where I am.

@Ta555 out of interest, what stops you wanting to go with the benzo, did you have a bad experience with it?

Those who have procedural sedation with propofol usually do not remember. Propofol is known as "milk of amnesia". Propofol is usually an option for procedural sedation. You can talk to your anesthesiologist about that. I wish you well.

 

[Ta555]

It varies quite a bit. Some people can take hours. Some minutes. Most people are unconscious very quickly either way.

I've had endoscopy with midazolam. I have never forgotten the experience. I've also had a midazolam and fentanyl combination. Each time they used local anaesthetic spray in the throat alongside it. I've remembered each procedure. I'm not sure if propofol is an option where I am.

@Ta555 out of interest, what stops you wanting to go with the benzo, did you have a bad experience with it?

I had Midazolam and fentanyl a few years ago and I woke up sick and nauseous and dizzy and feeling gross and not remembering a thing. Propofol apparently doesn't cause sickness or nausea.
I don't want to go with the benzo again because of the sickness but also because I had a bad experience with taking benzos and amitriptyline a few months ago and the thought of being pumped full of benzos makes me scared it will do a number on my brain.

 

[Smart No More]

I had Midazolam and fentanyl a few years ago and I woke up sick and nauseous and dizzy and feeling gross and not remembering a thing. Propofol apparently doesn't cause sickness or nausea.
I don't want to go with the benzo again because of the sickness but also because I had a bad experience with taking benzos and amitriptyline a few months ago and the thought of being pumped full of benzos makes me scared it will do a number on my brain.

Hey. Yeah, I can understand that. It's not very beneficial for cognition. I never went out with the combo myself. I've always still been awake. I guess the dose must have been low.