I think I'll drink the N in less than 2 hours..

[everwhatever]

ratchet was my first choice, can't manage it because of my disability though. But I think it's better than N, if you can work it.

I used ratchet, but it didn't work.

 

[Sonnenblume]

I used ratchet, but it didn't work.

you didn't get dizzy? how did you do it, exactly?

 

[everwhatever]

you didn't get dizzy? how did you do it, exactly?

Yeah, I don't know how to say, I felt only a headache and a panic, this stuff was just disgusting for me, hanging is better I guess.

 

[Sonnenblume]

Yeah, I don't know how to say, I felt only a headache and a panic, this stuff was just disgusting for me, hanging is better I guess.

I would think that means you didn't get it high up enough on your neck. Physiologically it's very similar to hanging.

 

[Nate]

If you're really concerned about possible extrapyramid side effects of metoclopramide, you can take a combination of domperidone and ondansetron instead.

Metoclopramide is a D2-antagonist and 5HT3-antagonist. The EPS can occur with metoclopramide since it penetrates the blood-brain barrier. Domperidone is also a D2-antagonist but doesn't penetrate the blood-brain barrier as much, so you still get the anti-emetic effects with a much smaller risk of EPS.

Ondansetron is a 5HT3-antagonist, so taking that with domperidone is essentially the same as taking metoclopramide.

If you want to take just a single dose, you can take 40 mg domperidone and 16 mg ondansetron.

Ohh this is

If you're really concerned about possible extrapyramid side effects of metoclopramide, you can take a combination of domperidone and ondansetron instead.

Metoclopramide is a D2-antagonist and 5HT3-antagonist. The EPS can occur with metoclopramide since it penetrates the blood-brain barrier. Domperidone is also a D2-antagonist but doesn't penetrate the blood-brain barrier as much, so you still get the anti-emetic effects with a much smaller risk of EPS.

Ondansetron is a 5HT3-antagonist, so taking that with domperidone is essentially the same as taking metoclopramide.

If you want to take just a single dose, you can take 40 mg domperidone and 16 mg ondansetron.

would you say ondansentron is better than the anti-emetics supplied? Or would a combination of both be optimal before the final dose?

 

[El Topo]

Ohh this is
would you say ondansentron is better than the anti-emetics supplied? Or would a combination of both be optimal before the final dose?

What do you mean by "the anti-emetics supplied?" Are you referring to metoclopramide?

 

[Nate]

What do you mean by "the anti-emetics supplied?" Are you referring to metoclopramide?

Is that the one from A? I actually don't know the name, that's the one I'm trying to refer to, but I'm unclear on if it's supplied really and what exactly it is. I do have some odansentran in my cabinet though so maybe I can make it useful.

 

[angie]

A supplies cirulan anti emetic think its similar to reglan i think

 

[El Topo]

Is that the one from A? I actually don't know the name, that's the one I'm trying to refer to, but I'm unclear on if it's supplied really and what exactly it is. I do have some odansentran in my cabinet though so maybe I can make it useful.

Yes, A includes metoclopramide. If you have ondansetron, you can take them together, but I don't think it would be necessary.

 

[bluebzh]

hi , do you think it's ok to take 40 grams of domperidone alone , 40 minutes before N ?

 

[Anje]

I know of one person who took 40mg total and did fine. They used A's instructions.

Whats a instruction? Is it 40mg meto an hr before?

 

[Final Escape]

Goodbye and good luck :) I'm jealous I wanna go now too.

 

[Pointlesslife]

How did you get nembutal?

 

[naia_]

We have never talked but I wish you a good journey.

Be blessed.