Lots of things
can cause necrosis. For example, an overdose of Tylenol could cause that. But are they strong or likely chances for either Tylenol or SN? No, not really.
Methemoglobinemia
can potentially lead to tissue necrosis,
though it is not a common direct consequence [
1][
2]. When oxygen delivery to tissues is compromised, it can lead to ischemia, and in severe cases, this lack of oxygen
can result in tissue necrosis in the skin, extremities, muscle tissue, organs (most suspetible would be the kidneys but this is
exceedingly rare [
3].
However, to my knowledge are no reported cases of this happening, but you can and should certainly research more if this a concern and then report back with findings however keep in mind that one-off cases are not a great indicator. However, they might exist to show it is of course
possible then one can also compare the volume of instances where it
did not in order to ascertain the risk factor. I would feel confident that it is a very low percentage based on some of the findings included in this post.
You can review this posts [
4] regarding post-failure outcomes as well for a better picture. Thus far, I personally have not read of anyone having any permanent damage but as with everything, these are just available reports but are the best indications we have; thus far there does not appear to be any. But this could of course change with time and more data becomes available, of course. There is always a chance though so it is not a 0% thing by
any means. You can make your own determinations based on thourough research though.
Not sure if this helps at all but I hope you find everything you are looking for and wish you all the best.
