Absolutely, at least that has been my experience (I won't claim it's universal). I've even ended therapy after realizing I could do just that. I often say things like, "I refuse to be controlled by this feeling," or "This is difficult for me, so I'll succeed out of spite." It's a kind of undirected anger that harms no one, serving as a spark in my life.
Well, that's probably unique to each individual. For me, it's as simple as feeling I've experienced enough of life™. I disagree with the notion that I should just watch life repeat itself ad nauseam, waiting to perish. I know how to be happy and lead an enjoyable and fulfilling life, but it no longer holds enough interest for me to want to continue living. This might not make sense to many, but that's the beauty of freedom - it really really really doesn't matter.