Sorry to bump this thread, and I know that medications still retain some potency long after their expiration date. I have some meto which expired in 2017, though, and was wondering if anyone had some idea how much would be enough to take with SN for the desired effect. (I know it will just be an estimate, but just curious if anyone has a ballpark range).
You can't know for sure. I took the time to read these articles which are about drugs in general, not metoclopramide specifically :
Are expired drugs safe and does the medicine expiration date really matter?...
www.health.harvard.edu
...
www.health.harvard.edu
Hospitals and pharmacies are required to toss expired drugs, no matter how expensive, vital or scarce. And that's even though the FDA has long known that many remain safe and potent for years longer.
www.npr.org
Do expired drugs lose their potency? Is it safe to take expired medications? Find out with this comprehensive guide about drug expiration dates by Drugs.com.
www.drugs.com
Based on the information in them, here's what I would personally do if I were in your situation, keep in mind this is just my opinion :
1) If possible, get meto which is not expired and use that instead
2) If not, use the expired meto but without increasing the dosage at all or only a little as it's possible that it's still quite potent.
The stat dose is already quite a high dosage when you look at what it says on the medical leaflet (understandable considering we need the effect to be strong to avoid vomiting the poison) so if I took even more, I'd be worried that the drug was still more potent than expected and end up ingesting much more than recommended, increasing
the risk of side-effects, some of which can be particularly nasty. Nausea and vomiting are some of the possible side-effects, it would be counter-productive.
Also I would prepare a second dose of SN to drink in case I vomit.
Edit : I forgot about the possibility of a meto regimen over 2 days, if you decide to increase the dosage, it may be a safer option since it would be accumulating in your system gradually rather than taking a lot once so if you get problematic side-effects, you'd have the time to notice before taking the SN.