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outnout

Member
Sep 22, 2025
7
I know ODs have pretty low likelihood of success in general based on statistics and aren't discussed often - but that takes into account all the benign substances OTC and rx people try that have no chance. Could this maybe be a viable option?

3 g methadone
20 mg clonazepam
20 mg clonidine

Assuming
- all taken orally
- pre dosed with zofran for multiple days
- no tolerance
- no chance of being found
- hopefully no vomiting within the first hour

How would it compare to SN for succes rate? SN would be my choice if I couldn't feel confident in the OD. PPH only rates SN success at 6/10 and it almost seems like this might have a better shot?
 
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EmptyBottle

EmptyBottle

🔑 Friends with Aera23
Apr 10, 2025
1,173
- hopefully no vomiting within the first hour

I cannot guarantee that. Also, the combo does seem more potent than other drugs... but naloxone exists... and benzo OD can be a nightmare.
 
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outnout

Member
Sep 22, 2025
7
The vomiting part scares me. I would be alone and no chance for naloxone to intervene. What do you mean about benzo OD? How it feels?

Does anyone know about the respiratory effects of methadone vs other opiates? Seems like fentanyl is a better option because it has a quick onset..but at the same time, methadone is continuously building up in the body because of the long half life and resp depression would just continue to peak over the course of hours?
 
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EmptyBottle

EmptyBottle

🔑 Friends with Aera23
Apr 10, 2025
1,173
The vomiting part scares me. I would be alone and no chance for naloxone to intervene. What do you mean about benzo OD? How it feels?

Does anyone know about the respiratory effects of methadone vs other opiates? Seems like fentanyl is a better option because it has a quick onset..but at the same time, methadone is continuously building up in the body because of the long half life and resp depression would just continue to peak over the course of hours?
small risk of brain damage, plus the side effects of benzos occuring for a while after the main effects wear off (assuming one has been given naloxone).

While I hear that methadone OD can be dangerous (risk of death), I cannot be certain what dose is needed, nor the risk of vomiting, etc.
 
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outnout

Member
Sep 22, 2025
7
Damn this sucks. Probably just a bad idea, I'm desperate. I wish nitrogen tanks would deliver to residential addresses
 
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NearlyIrrelevantCake

NearlyIrrelevantCake

The Cake Is A Lie
Aug 12, 2021
2,100

 
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outnout

Member
Sep 22, 2025
7
Wild.. PPH makes it sound like it's actually feasible, but I guess not
 
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