It's possible. I don't like anime in general, but one series that I fell head over heels with has actually extended my life. It's pathetic. When fandom stuff stops making me "happy" enough to continue is when I'll CTB. It's been four years, but I feel like I've exhausted all content so I enjoy it less and less. And fanmade content irritates me because I care about the characters too much.
Other than that, I quite enjoyed Fruits Basket and Ruroni Kenshin, but I've heard the manga is better in both cases. I also prefer the artstyle of older stuff. TV and movies don't interest me in general, though.