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Maybe the end

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May 2, 2020
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I have seen in the PPH that Propranolol should be taken with SN at the same time. But there are members here who take Propranolol an hour before drinking SN. Anyone have idea that which method is better?
 
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theguineapigking

theguineapigking

Useless piece of trash
Dec 5, 2019
593
Definitely before. If you take it with SN, it won't kick in fast enough before your heart beat raises and you eventually pass out anyways from sn(while having a fast beating heart) Propranolol is a 'luxury' medicine in the case of taking sn. It basically just helps with your heart beating fast due to sn and anxiety. It can help with comfort basically. The whole idea is that it helps you have a more peaceful experience with sn. To do so, it must kick in first.


Propranolol doesn't do anything to make sn absorption more effective or faster. It is simply used to keep your heart rate more normal, that's it.


If you need to talk at all, I'm here for you dude. Please be sure you truly want to die before going through with anything. Many people panic and call the police after taking sn. I don't want you to go through unnecessary pain.


Best wishes.



Ps. Check out Stan's guide in the resource section. It details sn and the meds pretty well.
 
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Jumper Geo

Jumper Geo

Life's a bitch and then you die.
Feb 23, 2020
2,910
Hiya,

Please find the link below I hope it's helpful, I have researched how long it may take to be effective and the dosage.

https://sanctioned-suicide.net/threads/soon-to-be-goodbye.37936/post-707050

Cheers

Geo
 
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M

Maybe the end

Member
May 2, 2020
20
Thank you for @theguineapigking @Jumper Geo 's kind reply.
 
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autumnal

autumnal

Enlightened
Feb 4, 2020
1,950
[...]
Propranolol doesn't do anything to make sn absorption more effective or faster. It is simply used to keep your heart rate more normal, that's it.
[...]

The PPH does emphasise the role of Propranolol in potentiating SN. Has that been disproven anywhere?
 
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Blu_1

Blu_1

Love, until you can love no more IG: trueblue_1010
Mar 13, 2020
147
The PPH does emphasise the role of Propranolol in potentiating SN. Has that been disproven anywhere?
I also wonder about the same thing.
 
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braketimez

braketimez

Specialist
Mar 15, 2020
340
The PPH does emphasise the role of Propranolol in potentiating SN. Has that been disproven anywhere?

Yeah, I don't know why people say propranolol is just for a calming effect. The PPH gives a pretty detailed explanation as to how the hypoxia process is sped up with a beta blocker.
 
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Blu_1

Blu_1

Love, until you can love no more IG: trueblue_1010
Mar 13, 2020
147
Yeah, I don't know why people say propranolol is just for a calming effect. The PPH gives a pretty detailed explanation as to how the hypoxia process is sped up with a beta blocker.
If PPH's is indeed the "better" (potentiating) option it will take 1 or 2 gm of propranolol mix with SN. (1 or 2 gm of that is not easy to acquire.) Of course my comprehension could be incorrect.

Hence the question if propranolol as a "calming agent" is an alternative to the above.
 
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GoodPersonEffed

GoodPersonEffed

Brevity is my middle name, but my name was TL
Jan 11, 2020
6,727
There have been discussions on the forum both about how and when to take propanolol for reducing the tachycardia caused by SN, as well as taking propanolol to potentiate the SN.

Personally, if I go with SN, I will take two doses of propanolol as part of the prep regimen, as noted in the quote below, and I will dissolve a high dose of propanolol in the SN mix to potentiate the SN.


@GrizzlyGrapefruit gave me this resource. I wanted to take propanolol to reduce or prevent tachycardia as I really dislike it and it's one of the most common SN symptoms. But I haven't seen anywhere on SS when it's best to take propanolol in the method, only that it can be added. (This is not the same as taking a high dose of propanolol at the time of SN ingestion for potentiation as suggested by Nitschke.)

@GrizzlyGrapefruit commented it takes 1-4 hours for propanolol to reach its potential, and that a lower rather than higher dose is recommended, as per this study, for supine tachycardia. So I'm adding it to my method, 20 mg at the start of my 4-hour fast, 20 mg two hours in.

I will still be taking 1-2 g propanolol with the SN, but did not think it would have time to mitigate the tachycardia, and in fact propanolol OD can cause tachycardia, so it's my hope that the earlier low dose may help to mitigate this. I do not experience calming with a low dose of propanolol, so no bonus effect there.
 
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Blu_1

Blu_1

Love, until you can love no more IG: trueblue_1010
Mar 13, 2020
147
@GoodPersonEffed That will be a lot of p.
 
GoodPersonEffed

GoodPersonEffed

Brevity is my middle name, but my name was TL
Jan 11, 2020
6,727
@GoodPersonEffed That will be a lot of p.

Yes I'm aware. I've done my research, that's my choice. It is basically a dual OD of SN and propanolol.
 
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braketimez

braketimez

Specialist
Mar 15, 2020
340
Yes I'm aware. I've done my research, that's my choice. It is basically a dual OD of SN and propanolol.
Is it a lot of propranolol? I thought people with blood pressure issues take a ton more.
 
GoodPersonEffed

GoodPersonEffed

Brevity is my middle name, but my name was TL
Jan 11, 2020
6,727
Is it a lot of propranolol? I thought people with blood pressure issues take a ton more.

40 mg over a couple hours is a small amount.

1-2 g taken with the SN is a major amount and is not just a potentiator, but a supplemental OD. That amount can be fatal without SN, though 8 g minimum is recommended for an intentional propanolol OD, and even that can be survived, it's not a reliable method on its own because individual reactions can vary.
 
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braketimez

braketimez

Specialist
Mar 15, 2020
340
40 mg over a couple hours is a small amount.

1-2 g taken with the SN is a major amount and is not just a potentiator, but a supplemental OD. That amount can be fatal without SN, though 8 g minimum is recommended for an intentional propanolol OD, and even that can be survived, it's not a reliable method on its own because individual reactions can vary.

Ah, so are you planning on taking 1-2g? Can't high dose beta blockers bring about seizures? Scary way to OD. But yeah, if it's combination with SN, that makes sense.
 
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GoodPersonEffed

GoodPersonEffed

Brevity is my middle name, but my name was TL
Jan 11, 2020
6,727
Ah, so are you planning on taking 1-2g? Can't high dose beta blockers bring about seizures? Scary way to OD. But yeah, if it's combination with SN, that makes sense.

Also planning on taking a high dose of diazepam for seizure prevention.
 
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Busdriver

Busdriver

Mage
Feb 11, 2020
513
Also planning on taking a high dose of diazepam for seizure prevention.

Very interesting.
I read in PPH that propranolol induces death faster, because the lower resulting heartbeat slows down the process of reconverting methemoglobin to hemoglobin. So death occurs quicker.

About the benzo, are you going to take SN the moment you are about to fall asleep from the benzo, so that you won't experience the discomfort of the 1st 20 minutes?
Some members here secretly want their SN to mimic the peacefulness of N by timing benzos in such a way that they want to take SN after feeling super drowsy and fall asleep quickly.
 
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GoodPersonEffed

GoodPersonEffed

Brevity is my middle name, but my name was TL
Jan 11, 2020
6,727
Very interesting.
I read in PPH that propranolol induces death faster, because the lower resulting heartbeat slows down the process of reconverting methemoglobin to hemoglobin. So death occurs quicker.

About the benzo, are you going to take SN the moment you are about to fall asleep from the benzo, so that you won't experience the discomfort of the 1st 20 minutes?
Some members here secretly want their SN to mimic the peacefulness of N by timing benzos in such a way that they want to take SN after feeling super drowsy and fall asleep quickly.

Thanks for the info from the PPH explaning the rationale for propanolol as a potentiator.

Yes, I would do my best to take the SN/propanolol mix when I'm about to fall asleep, but I don't know how well I'll be able to manage that. I may have to take half of my diazepam and save the other half in case I fall asleep too quickly. I'm not really hoping that it will make unconscious so I don't experience the SN symptoms, although that would be nice, but rather to lose consciousness more quickly than without it, and to prohibit seizures.

I've tested diazepam and I start feeling the effects in 20 minutes, but it takes over an hour to feel the full effects. I have no idea how that's going to work out taking a high dose. I could fall asleep just as I'm about to drink the SN, or during, so I'll probably have to drink it as soon as I feel like, wow, I'm really starting to get drowsy.
 
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enjolras

enjolras

Dead are useless if not to love the living more
Feb 13, 2020
1,293
Less pulse preventing the compensation of methemoglobin, less oxygen disposed by the brain.

Of interest, a member recently survived 2g of Propranolol, mixed with other stuff : benzo (large amount), alcohol (large), nembutal (minimal amount) and an opiod pain reliever (low amount). He reported waking up after 36 hours with pain everywhere. Wondering if it was including heart and chest discomfort, didn't dare to ask, and specifically which med, if not Propranolol, essentially caused it (so long immobility may have played a role on body parts due to blocked circulation, etc)

Just saying, if ODing on Propranolol, maybe be sure not too abort the SN with ambulance. You never know how unpleasant it will be, or can we estimate it ?
The PPH does emphasise the role of Propranolol in potentiating SN. Has that been disproven anywhere?

It has been disproven in the PPH: 2g > 1g
Sorry, disengaging sarcasm :(
 
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GoodPersonEffed

GoodPersonEffed

Brevity is my middle name, but my name was TL
Jan 11, 2020
6,727
Less pulse preventing the compensation of methemoglobin, less oxygen disposed by the brain.

Of interest, a member recently survived 2g of Propranolol, mixed with other stuff : benzo (large amount), alcohol (large), nembutal (minimal amount) and an opiod pain reliever (low amount). He reported waking up after 36 hours with pain everywhere. Wondering if it was including heart and chest discomfort, didn't dare to ask, and specifically which med, if not Propranolol, essentially caused it (so long immobility may have played a role on body parts due to blocked circulation, etc)

Just saying, if ODing on Propranolol, maybe be sure not too abort the SN with ambulance. You never know how unpleasant it will be, or can we estimate it ?

Respectfully, I think this comment gets a bit off topic, though I don't think that was your intention.

Propanolol OD without SN is a different subject, it requires a minimum of 8g, and there are medical reports of survival at 12g. The person you're talking about combined different meds, no SN.

I think in your final paragraph, you were trying to show how the comment relates to this thread with regard to combining propanolol and SN and aftereffects of survival, but I didn't understand it.
 
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Erase.myself

Erase.myself

My body is a prison
Jan 4, 2020
198
I have a question. So, I was prescribed Propanolol last year, and it actually shouldn't have been prescribed to me because it's counteracts with my asthma. I guess people with asthma can have trouble breathing when it's taken ? I don't recall but when I was drunk and just lost my twin sister I impulsively took a bottle of it to try and ctb. Long story short, I got cops called and ended up in ICU for couple days with fucked up blood sugar amongst other issues.

If I'm able to get this medication again somehow, will the fact that I have asthma be counter productive to taking SN, such as is some type of difficulty?
 
GoodPersonEffed

GoodPersonEffed

Brevity is my middle name, but my name was TL
Jan 11, 2020
6,727
I have asthma and propanolol does exacerbate it. Also, I did a blood test with SN, put the SN directly on the open wound (don't try this), and after a few minutes I felt the SN go up my arm and down into my chest, and I began having trouble breathing. My assumption is that if I do this method, I will have trouble breathing. Shortness of breath is one of the commonly reported symptoms of SN, I made a list of symptoms and how many reported each, and trouble breathing was in around 25% of cases of those who supposedly completed ctb and reported symptoms after taking it.
 
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Erase.myself

Erase.myself

My body is a prison
Jan 4, 2020
198
I have asthma and propanolol does exacerbate it. Also, I did a blood test with SN, put the SN directly on the open wound (don't try this), and after a few minutes I felt the SN go up my arm and down into my chest, and I began having trouble breathing. My assumption is that if I do this method, I will have trouble breathing. Shortness of breath is one of the commonly reported symptoms of SN, I made a list of symptoms and how many reported each, and trouble breathing was in around 25% of cases of those who supposedly completed ctb and reported symptoms after taking it.

Thank you for your response to my post. Trouble breathing sounds scary, even though it's common (I did read your thread about the SN/symptoms reported) , the fact that it wasn't 100% of the cases provides me with some sort of solace. I suppose I'll go with not taking the Propanolol, and hope it minimizes the chance of shortness of breath in my case. I also read in @Moonicides documentation of SN, that she seemed to have gasped for air a couple times, but that also her symptoms didn't last super long.
 
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enjolras

enjolras

Dead are useless if not to love the living more
Feb 13, 2020
1,293
Respectfully, I think this comment gets a bit off topic, though I don't think that was your intention.

Propanolol OD without SN is a different subject, it requires a minimum of 8g, and there are medical reports of survival at 12g. The person you're talking about combined different meds, no SN.

I think in your final paragraph, you were trying to show how the comment relates to this thread with regard to combining propanolol and SN and aftereffects of survival, but I didn't understand it.

I made the first remark to stipulate 1-2g cannot be considered a fatal "backup" on its own. It really seems potentiation. You approached the matter with further refinement, coupling it with a potentiator for Propranolol (if I'm not mistaken, please correct me) which is unique and unseen elsewhere.
(not arguing on the rest, you're perfectly right!)

Regarding my second paragraph, it was unrelated to first. Don't mean to propagate the confusing logic of PN. Please disregard it completely. Hope @Erase.myself will find peace... (and you too)
 
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autumnal

autumnal

Enlightened
Feb 4, 2020
1,950
It has been disproven in the PPH: 2g > 1g
Sorry, disengaging sarcasm :(

The PPH revising the Pronranolol dose from 2g down to 1g doesn't in any way disprove its stated purpose of being an SN potentiator. The original 2g may have been stated in error, or they may simply have gleaned more data from attempts that show 2g is either too much (and harder to obtain or hoard in those quantities), or creates unwanted side effects that offset the benefits. Either way, the 1g is still currently stated as being for SN potentiating purposes.
 
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Jumper Geo

Jumper Geo

Life's a bitch and then you die.
Feb 23, 2020
2,910
The PPH does emphasise the role of Propranolol in potentiating SN. Has that been disproven anywhere?

I have been reading the threads on Propranolol, I don't think Stan was a big fan of the PPH, but some good has come out of reading the threads and using Google to find answers, I have decided to increase the amount to my original 120 mg instead of the 80 mg, so taking 3 tablets, I thank everyone for this discussion, I will just crush them and swallow them in a Rizla.

Looking at the people who ctb using the SN most just used the basic drugs needed Antiemetic, Antacid, Pain Killer and SN in some ways I wish I just stuck to the basics, planning to ctb I never realised how much study and reading would be involved, this should be a degree course.

https://sanctioned-suicide.net/thre...l-and-type-on-benzos-for-sn.24416/post-482850
 
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theguineapigking

theguineapigking

Useless piece of trash
Dec 5, 2019
593
The PPH does emphasise the role of Propranolol in potentiating SN. Has that been disproven anywhere?
I'm not sure honestly. I was going based on Stan's guide. I've never heard of propranolol helping the sn method work better. Stan said it was used simply to keep the heart rate normal, for comfort reasons.

I'm sorry if I was somehow incorrect. I don't have any other sources, such as the PPH.
 
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A

Aap

Enlightened
Apr 26, 2020
1,856
Propranolol is used in Oregon in the cocktails when barbs aren't available along with a ton of morphine and Valium. The reasons are twofold when everything is consumed at once. The primary reason is to prevent compensating tachycardia that occurs when resipiration and bp slow. The secondary reason (and a distant second) is that propranolol can induce fatal arrhythmias. With SN and taken before, it will reduce physical signs of anxiety and have the effect of preventing or reducing tachycardia secondary to methemoglobinemia.
 
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autumnal

autumnal

Enlightened
Feb 4, 2020
1,950
I'm not sure honestly. I was going based on Stan's guide. I've never heard of propranolol helping the sn method work better. Stan said it was used simply to keep the heart rate normal, for comfort reasons.

I'm sorry if I was somehow incorrect. I don't have any other sources, such as the PPH.

No need to apologise, Stan's guide is certainly treated here as the definitive resource, but we shouldn't forget that the PPH is presumably where SN was first described and developed. I don't know if Stan explained anywhere why he disagreed with the PPH on the Propranolol aspect, nor whether his medical experience rivaled that of the PPH authors.

It would probably do everyone good to read the PPH, even if people disagree with it on certain aspects, it is one of the most definitive resources in suicide methods, and helps you understand the developments that came after it.
 
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A

Aap

Enlightened
Apr 26, 2020
1,856
i suspect some, especially the immediate, vomiting is due to anxiety, and I think this is where propranolol amd/or benzos in moderate doses can assist when taken shortly before. My primary concern with taking 1 or 2g of propranolol with sn is actually inducing angina due to arrhythmia or just general low cardiac output and perfusion before unconsciousness sets in. Unfortunately, I don't know if there is much evidence to prove or disprove this concern.
 
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