It really depends from which angle you view it from: the normal human angle, or the abnormal human angle.
From the normal human perspective, life is fine. That's kind of obvious. Most people go about their days with not a care in the world. No thoughts of depression, no major anxiety, no panic attacks, no hostility towards the world or fear of their own thoughts. They just live, and that will likely be all they ever do, until one day they rot and return to the Earth. Civilisation has made life better for them, and the environment would've killed them off before any of them reached 50 or so, or at least the vast majority, as a result of predators and whatnot.
From the abnormal human perspective, it's completely different. By abnormal, I mean anyone contemplating suicide, with mental or physical disorders, just anything that deviates them from the norm. Civilisation has made these lives hell on Earth, and I don't think there is a more apt description of it. In the wilderness, you, at the very least, had the ability to go out in a quick manner. Do something heinous, someone kills you, that's it. In an even more primitive environment, you're probably going to die of some disease or predator ruining your body or mauling you respectively before you get to the point that you start to have dreadful thoughts. And even then, prior to civilisation, or at least prior to sapience, we weren't even smart enough to feel like dogshit and want to commit suicide, outside of instinctual desire. But in civilisation, and as sapience has taken hold and proven itself to be the accidental apex of evolution, your suffering is prolonged. You aren't permitted death and legally haven't been until the last few decades and, even them, you have to go through a lengthy process to go for it. Want to buy an opiate to CTB on? Tough shit, it's illegal. Finally get your hands on some? You might either fail, or you might be guilt-tripped into not taking the plunge. Anyone struggling with depression or just having a shitty life are forced to live it out regardless of what you want. If you die, that's one less cog to turn society (potentially). One less cog to squeeze money into the rich man's pocket, one less cog to mindlessly consume media and food and suffer until your pleasant demise. That is what the experience is from the abnormal human perspective. In this instance, in short, yes, civilisation and humanity's sapience/lust/ego/stubbornness made the world into hell on Earth.