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whitefeather

whitefeather

Thank the gods for Death
Apr 23, 2020
519
nem01-0005-02.jpg
 
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fruit-loops

fruit-loops

Student
Jun 27, 2021
150
Thanks for the information. 20 to 25 celsius is a very narrow range to mantain, you may need something like an adjustable electric wine cellar or something like that :/
 
whitefeather

whitefeather

Thank the gods for Death
Apr 23, 2020
519
Label states "PROTECT FROM FREEZING" " AVOID EXCESSIVE HEAT" The narrow range of temps is just to sell more product , like 2 YR EXP DATE on everything under the sun
 
J

juraviel

PL
Aug 11, 2021
414
says nothing on the label that it can be kept in cold. what are you saying? besides would that extend or shorten shelf life
 
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Foresight

Foresight

Enlightened
Jun 14, 2019
1,393
says nothing on the label that it can be kept in cold. what are you saying? besides would that extend or shorten shelf life
That's what I'm wondering. It says room temperature?
Label states "PROTECT FROM FREEZING" " AVOID EXCESSIVE HEAT" The narrow range of temps is just to sell more product , like 2 YR EXP DATE on everything under the sun
They put that for the pharmacy to store it correctly. Are you saying to sell more product they have it left at room temperature rather than refridgerate? I'm confused.
 
Hercules

Hercules

Arcanist
Jan 31, 2021
408
You can keep the N in the refrigerator if you want, but it isn't necessary. Ideally you should store the N at room temperature and keep it in a cool dry place away from light. At the vets office, they keep the N in a dark storage room.

If you refrigerate it, make sure you store it in a dark airtight container in order to keep out the moisture and the light. Storing it in the refrigerator may help to extend the shelf life if you are storing it long-term as there would be less variation in tempature in the refrigerator. The important thing is to store it somewhere where the tempature is stable and avoid storing it in extreme humidity or cold conditions as this will cause the N to degrade faster.

In the PPH August 2021 edition it says

"The Storage of Nembutal Veterinary liquid comes in sealed, sterile glass 100ml bottles. It is best not to disturb the seal on the bottle until it is needed Do not break the seal or decant the liquid into another container as this will expose the drug to the air. Store the original bottles in a cool dark place. Refrigeration is fine, but do not freeze as the bottle can break The liquid should be clear and colourless. Any coloration or precipitation of the liquid means that further testing and assay will be required."
 
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Smart No More

Visionary
May 5, 2021
2,734
What I'm finding confusing on this is, what they actually mean by precipitation. I originally assumed they were referring to condensation but surely they would say that if that's what they meant. I have seen small bubbles sitting atop fluid in sealed bottles that have been sitting stationary for a very long time. Would this actually be what is referred to as precipitation?
 
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Hercules

Hercules

Arcanist
Jan 31, 2021
408
What confused me on this is, what exactly do they mean by precipitation. I originally assumed they were referring to condensation but surely they would say that if that's what they meant. I have seen small bubbles sitting atop fluid in sealed bottles that have been sitting stationary for a very long time. Would this actually be what is referred to as precipitation?
If there is precipitation, you will see small solid specks or crystals floating in the liquid. The liquid would also look cloudy or hazy.
 
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S

Smart No More

Visionary
May 5, 2021
2,734
If there is precipitation, you will see small solid specks or crystals floating in the liquid. The liquid would also look cloudy or hazy.
Would you agree that the word precipitation is misleading? Precipitation means essential grouped water molecules in the form of droplets or mist above 'ground' level.

I'm aware of the issue with separation and resulting cloudiness but don't feel they fall under precipitation. Honestly feel that Exit should offer an explanation because they charge for the info in the pph. Its very nonspecific on a topic that require specific detail/explaination given the consequences. It shouldn't be open to interpretation.

Would you agree?

Edit:

Ah, OK......

I originally searched precipitation. The results were all in line with my initial understanding of the word and often used in relation to weather.

After this I took another look at the bottle amd noticed it say precipitate. Small difference but significant. After searching precipitate I got the wiki result which makes total sense of it. Oddly it's still named precipitation but in a different context (chemistry) which is more in line with what @Hercules described. Link below....


I hadn't worried about any of this until this topic arose a fear that I had overlooked or misunderstood something. My mind is now at ease again. Though I'm still torn between fridge and room temp. I suspect that room temp is fine for the period covered on the use by date but if planning to keep it longer then refiridgeration makes sense. It's not uncommon for companies to undershoot use by dates for the obvious reason of avoiding litigation and the monetary benefit of it being replaced sooner than needed. Much like our electrical appliances have built in obsolescence (look it up, it's a thing) many products are deaigned not to last.

This aside, the permitted excursion range is above fridge temps which is concerning if choosing to store refrigerated. I'm not sure how I feel on that one as it could be interpreted as absolute and oitlined for scientific reason or it could be the excursion range suitable when stored in the intendwd acenario of dark room storage. The issue as I understand it is that when temperature fluctuates dramatically it causes the separation of components initially suspended in a solution. I'm tentatively interpreting this to indicate that, when stored at a stable cooler temperature there eill be little to no fluctuations in temperature until its bought out for use. Thus, hopefully extending its 'shelf' life much further than the expiry date. This does however seem somewhat of a risk in that, when it's finally removed from refridgeration it will come upto room temperature quite rapidly (perhaps in the sigestive system) and there may be the risk of it separating then. Given the speed it works though, would this even be an issue!?

I'm still uncertain which is the actual right way to store it long term/beyond expiry but it's clear from the label that refrigeration isn't considered correct.
 
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F

fizi22

Member
Nov 15, 2021
79
wait, so the light from a light bulb can damage the N?
 
S

Smart No More

Visionary
May 5, 2021
2,734
wait, so the light from a light bulb can damage the N?
That would dwpend on what type of bulb it is but I think the bulb is not the issue. It's the natural light from opening and closing the fridge. Maybe the bulb would be a contributing factor but the bulb is off when the fridge is closed.

Not hard to put the bottles in a bag or box. They come in boxes anyway.
 

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