I have not had any-even remotely-good experiences with psych meds, unless they were for sleep, or anxiety (and taken as needed, not every day). As far as antidepressants specifically, they just made me lose too much inhibition/self awareness, to the point I could have probably walked out of the house unclothed and not realized it.
My ability to humiliate and embarrass myself was heightened, and I sure as fuck don't need any more of that in my life.
And as someone else said, I was simply not myself. Same for other types of psych meds, like anti-psychotics, but those had a different effect, like locking a person out of their own head. As someone who is quite 'heady' and cerebral, that was unacceptable, my mind was my only escape from the daily torture of my existence, to close the door on that was a cruelty. Somehow, they think shutting down access to your field of thought-and forcing you back out into your insufferable reality-is somehow helpful.
Sure, the brain will be burdened with traumatic thoughts when that's all life offers for it to attach itself to, but it is also a tool for respite.
The problem with these medications, for a lot of people, is that they are provided to you on the false basis that you undoubtedly have some type of "chemical imbalance". This is likely false in enough cases that these meds-more often than not-GIVE you a chemical imbalance, rather than correct one already present.
They are not doing any type of biological test, it's all trial and error, and you are the guinea pig.