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N

nasttya

New Member
Nov 12, 2023
4
Most antiemetics are available by prescription. I have mirtazapine and chlorproxitene. I read on the wiki that they are used as an antiemetic. Is it possible to replace metoclopramide with them?
 
Kasumi

Kasumi

tired
Mar 3, 2023
511
Chlorprothixene is an dopamine antagonist as well as an H1 antagonist so it should work?? As far as my limited knowledge goes Dopamine receptor antagonists such as Meto or Domp work better than anti-histamines.

Mirtazapine is a 5-HT3 receptor antagonist and has shown anti-emetic effects, although it doesn't block Dopamine receptors as far as I know and Idk how it compares to drugs doing that.

My guess is Chlorprothixene is probably fine, though Mirtazapine is probably more for long term treatment of nausea any may have a weaker effect?
 

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