ambien/z drug tolerance and N

[insomni_yak001]

Hi yall,

So I have really awful insomnia and was on the devil's drug, ambien for 8 months (it left me without a sleep drive/ability to sleep, but that's besides the point). I became rapidly tolerant to a point where ambien or z drugs won't put me to sleep anymore.

I am in the process of buying N. I'm wondering if 2 bottles is enough given my tolerance to z drugs. (I am 5'3 and 130 lbs, so Im kind of small) I also have a long history taking anti-psychotics (for sleep, bad idea) which I believe the handbook said was another risk factor in N not working well.

Anyone else out there like me or have any advice? Do I need 3 bottles? Will this work at all?

Sending love--

 

[lostmylove]

My gut feeling is two will do the job and still be overkill due to your weight and height.

Probably best if you plan to not be found in 24 hours at very least though.

 

[insomni_yak001]

My gut feeling is two will do the job and still be overkill due to your weight and height.

Probably best if you plan to not be found in 24 hours at very least though.

Thank you for the input-- I'm worried because there's just no way to know how my tolerance will affect me except to take a leap of faith. Yeah, I think not being found *might* be the key, I'm just so scared I'll somehow wake up, or I won't be able to get all of it down without vomiting... or something painful will happen etc. :(

I get MASSIVE withdrawal symptoms (like it feels like my head lights itself on fire and I get so agitated I cant even tolerate the wind blowing because it's too *loud*) to gaba-ergics, so waking up post N (the strongest Gaba-ergic) would be the most painful thing in the world for many reasons-- so I want to get it right.

 

[lostmylove]

Thank you for the input-- I'm worried because there's just no way to know how my tolerance will affect me except to take a leap of faith. Yeah, I think not being found *might* be the key, I'm just so scared I'll somehow wake up, or I won't be able to get all of it down without vomiting... or something painful will happen etc. :(

I get MASSIVE withdrawal symptoms (like it feels like my head lights itself on fire and I get so agitated I cant even tolerate the wind blowing because it's too *loud*) to gaba-ergics, so waking up post N would be the most painful thing in the world for many reasons-- so I want to get it right.

I know what you're saying but I think you're overthinking and more worried about it failing than wanting to stay.

I really think 3 bottles would be too much and more likely to vomit drinking 3 than to. You may even not be able to finish 3 bottles without passing out. 2 bottles should be fine. I'm sure waking up post N would be traumatic for anyone I agree.

 

[Red Scare]

I wonder the same thing about taking gabapentin. I have been taking it the past week and a half to sleep, because I was withdraw from going cold turkey off of a daily fent habit. Gabapentin is the only things that's helped. Now I wonder if it will affect how N will work. I guess I could plan to stop taking the gabapentin for a week or two before I plan to ctb. Hopefully there won't be any issue, I'll be drinking two bottles. Like the op I am only 5'6 and weigh about 140 pounds.

 

[insomni_yak001]

I wonder the same thing about taking gabapentin. I have been taking it the past week and a half to sleep, because I was withdraw from going cold turkey off of a daily fent habit. Gabapentin is the only things that's helped. Now I wonder if it will affect how N will work. I guess I could plan to stop taking the gabapentin for a week or two before I plan to ctb. Hopefully there won't be any issue, I'll be drinking two bottles. Like the op I am only 5'6 and weigh about 140 pounds.

I wouldn't worry about Gabapentin -- while its structurally similar to GABA, it doesn't act on GABA-A or GABA-B receptors -- N works on GABA-A. As do benzos and z-drugs (which is why I was worried). I'm no expert but base on my understanding of Gabapentin you should be fine because it's not activating GABA-A.

 

[Sunset Limited]

I just did a google search about zolpidem. Since it is a GABA A receptor agonist, there is a potential for cross-tolerance with N. However, I don't think it will change the outcome. From what I've read, the highest dose at which pentobarbital addicts die is between 1.5 and 2 grams. So apparently even an N addict dies with a bottle of N. Still, I have read this information online and its reliability is questionable. I think unless someone is a 250kg giant addicted to N, there's little chance of surviving even with a bottle of N.

 

[BrokenBliss]

I wouldn't worry about Gabapentin -- while its structurally similar to GABA, it doesn't act on GABA-A or GABA-B receptors -- N works on GABA-A. As do benzos and z-drugs (which is why I was worried). I'm no expert but base on my understanding of Gabapentin you should be fine because it's not activating GABA-A.

Wikipedia: Despite the fact that gabapentin is a structural GABA analogue, and in spite of its name, it does not bind to the GABA receptors, does not convert into GABA or another GABA receptor agonist in vivo, and does not modulate GABA transport or metabolism.

 

[insomni_yak001]

I just did a google search about zolpidem. Since it is a GABA A receptor agonist, there is a potential for cross-tolerance with N. However, I don't think it will change the outcome. From what I've read, the highest dose at which pentobarbital addicts die is between 1.5 and 2 grams. So apparently even an N addict dies with a bottle of N. Still, I have read this information online and its reliability is questionable. I think unless someone is a 250kg giant addicted to N, there's little chance of surviving even with a bottle of N.

Thank you :)

 

[reddragon1]

I wonder the same thing about taking gabapentin. I have been taking it the past week and a half to sleep, because I was withdraw from going cold turkey off of a daily fent habit. Gabapentin is the only things that's helped. Now I wonder if it will affect how N will work. I guess I could plan to stop taking the gabapentin for a week or two before I plan to ctb. Hopefully there won't be any issue, I'll be drinking two bottles. Like the op I am only 5'6 and weigh about 140 pounds.

Hi. Just a quick question out of interest. If you had a fent problem wouldn't it just be easier to OD on fent since I have heard that it super potent and kill 0000's every year in usa?

 

[downndone2]

Hi. Just a quick question out of interest. If you had a fent problem wouldn't it just be easier to OD on fent since I have heard that it super potent and kill 0000's every year in usa?

I agree, fent would be my preferred but I dont have reliable access to it

 

[Red Scare]

Wikipedia: Despite the fact that gabapentin is a structural GABA analogue, and in spite of its name, it does not bind to the GABA receptors, does not convert into GABA or another GABA receptor agonist in vivo, and does not modulate GABA transport or metabolism.

Sorry for my late reply, but I just want to double check, this shouldn't cause any problems at all when taking N? I don't know if I'll be able to stop it's use before hand, it seems to be the only way I can get any sleep lately is by taking some.

 

[Smart No More]

Hi yall,

So I have really awful insomnia and was on the devil's drug, ambien for 8 months (it left me without a sleep drive/ability to sleep, but that's besides the point). I became rapidly tolerant to a point where ambien or z drugs won't put me to sleep anymore.

I am in the process of buying N. I'm wondering if 2 bottles is enough given my tolerance to z drugs. (I am 5'3 and 130 lbs, so Im kind of small) I also have a long history taking anti-psychotics (for sleep, bad idea) which I believe the handbook said was another risk factor in N not working well.

Anyone else out there like me or have any advice? Do I need 3 bottles? Will this work at all?

Sending love--

Hey, I know this is a relatively older thread now but I thought I'd jump in anyway. I have similar concerns to yourself. Having used z drugs and benzos I totally relate and honestly find my tolerance to them grows daily when I use them. It's quite scary and as a result I can only use them sporadically far apart. If you're still using them daily I'd suggest, if only foe peace of mind (so to speak) looking into tapering off them before you decide to use N to CTB. Even though the 200ml is aimed at overriding any outliers like ourselves it's still potentially going to take some time. For me I want it to be as quick as possible for a few reasons. Hence my suggestion. The other option I considered is loading up of the Z's and Benzo's alongside the 200ml but I can't help wondering if this is foolhardy in some way. For example there's a kind of reaction some people have to overdosing benzos where they essentially go into withdrawal instead. It's a paradoxical effect which I read about on various boards and sites. Though I think it happens at the lowet end over dosing where people are attempting to get effects recreationally and keep updosing due to the nature of feeling like you're not high when in fact you are. Another common phenomena amongst benzo users.

If you do decide to tackle a reduction of your meds I'd suggest switching to a long acting benzo and tapering that. Diazepam is the first port of call and there's a well respected and published doctor and author you might like to look up for guidance. A doctor Ashton. The Ashton manual and guide is available all over the web and the info is all free I believe. Also the forum Bluelight is a good source for info, guidance and support on these matters.

Z's and benzo's are great in short bursts but soon stop working and end up being a ball and chain. Much like some opiates. I hope you manage to find your way through the other side. Best of luck to you! :)