Phenylhydroxylamine
Member
- Jun 28, 2024
- 10
Hello, I've lurked this site over the years (although the last year I've not been watching it much) and decided to finally make an account because I feel I have some potentially useful information to share.
As you probably know, sodium nitrite is an effective CTB method because it induces methemoglobinemia, which seems to be a relatively painless way to die. I think it can cause headache and some stomach discomfort, but personally I feel I can tolerate that. Anyways, I was researching other substances that can cause methemoglobinemia and found that both lidocaine and benzocaine can induce it. These are both easy to obtain online (at least here in the US), with benzocaine being the easiest to obtain. When benzocaine is metabolized by the liver, a redox cycle occurs with phenylhydroxylamine and nitrosobenzene, producing o2- (superoxide), which turns your hemoglobin into methemoglobin. Chubbyemu has a good video on this on YouTube, just look up "Chubbyemu mouth numbing spray", where he talks about a man who drank a bottle of mouth numbing spray containing (probably 5%) benzocaine.
Okay now I'll talk about important details. First off, there seems to be 2 different methods used to dissolve benzocaine to make a solution for mouth numbing sprays. Benzocaine is not soluble enough in water to make a numbing solution, so other things must be used. The first method is to use alcohol (ethanol), since benzocaine is quite soluble in it. The other is to use polyethylene glycol, often one called "PEG 400". I believe this is what mouth numbing sprays that say "alcohol free" are using. In my opinion, the PEG 400 solution would be best if attempting to ingest benzocaine because the PEG mostly passes through your body without interacting, thus reducing the amount of interactions to consider.
Lastly, I had the idea for just making phenylhydroxylamine and consuming that directly. This would bypass the need for the liver to produce it from the benzocaine, and would maybe work better. It is also more water soluble, which also happens to be the reason why the liver turns benzocaine into it in the first place. Surprisingly, it doesn't seem too hard for the home chemist to make. All you need to do is reduce nitrobenzene with zinc dust. Nitrobenzene can be produced by nitrating benzene using nitric acid and sulfuric acid, and benzene can be produced by reacting sodium benzoate (easy to acquite food preservative) with sodium hydroxide, and then distilling off the benzene.
Anyways, hopefully sometime soon I will be attempting with this, and I will try and get some trusted 3rd party on this forum to witness it and report back to you all how it goes :)
As you probably know, sodium nitrite is an effective CTB method because it induces methemoglobinemia, which seems to be a relatively painless way to die. I think it can cause headache and some stomach discomfort, but personally I feel I can tolerate that. Anyways, I was researching other substances that can cause methemoglobinemia and found that both lidocaine and benzocaine can induce it. These are both easy to obtain online (at least here in the US), with benzocaine being the easiest to obtain. When benzocaine is metabolized by the liver, a redox cycle occurs with phenylhydroxylamine and nitrosobenzene, producing o2- (superoxide), which turns your hemoglobin into methemoglobin. Chubbyemu has a good video on this on YouTube, just look up "Chubbyemu mouth numbing spray", where he talks about a man who drank a bottle of mouth numbing spray containing (probably 5%) benzocaine.
Okay now I'll talk about important details. First off, there seems to be 2 different methods used to dissolve benzocaine to make a solution for mouth numbing sprays. Benzocaine is not soluble enough in water to make a numbing solution, so other things must be used. The first method is to use alcohol (ethanol), since benzocaine is quite soluble in it. The other is to use polyethylene glycol, often one called "PEG 400". I believe this is what mouth numbing sprays that say "alcohol free" are using. In my opinion, the PEG 400 solution would be best if attempting to ingest benzocaine because the PEG mostly passes through your body without interacting, thus reducing the amount of interactions to consider.
Lastly, I had the idea for just making phenylhydroxylamine and consuming that directly. This would bypass the need for the liver to produce it from the benzocaine, and would maybe work better. It is also more water soluble, which also happens to be the reason why the liver turns benzocaine into it in the first place. Surprisingly, it doesn't seem too hard for the home chemist to make. All you need to do is reduce nitrobenzene with zinc dust. Nitrobenzene can be produced by nitrating benzene using nitric acid and sulfuric acid, and benzene can be produced by reacting sodium benzoate (easy to acquite food preservative) with sodium hydroxide, and then distilling off the benzene.
Anyways, hopefully sometime soon I will be attempting with this, and I will try and get some trusted 3rd party on this forum to witness it and report back to you all how it goes :)
