Veterinary literature describes 15-30 minutes of analgesia, with sedative effects lasting as long as 1-2 hours when xylazine is given intramuscularly. This occurs at a dose range of approximately 0.5-4 mg/kg with 47-70 mg/kg suggested as the fatal dose range (LD50). Intravenously, the drug is rapidly absorbed, metabolized and eliminated with distribution concentrated in the central nervous system and the kidneys. Information in humans is extremely limited [8]."
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