Based on personal experience, it can be a mixed bag and bad trips can be just as life altering. I had one good experience and then one incredibly bad trip. It was positively terrifying as I thought I was dead and in hell. Yes, I appreciate this was the representation of an ego death, but it was also on the side of a bona fide psychotic break as well. Thankfully it wore off (and that's what you need to keep repeating to yourself and have written down nearby). I have used smaller doses since, but they made me incredibly anxious and depressed. I'm not sure whether it was the strain/producer or what, but I will never go back unless under the care of a doctor.
Microdosing appears to be helpful, especially with the right strain and from a trusted producer. It is a very subjective thing and hopefully you are under the care of a physician or at bare minimum, you're purchasing from a trusted producer who has provided conservative usage guidelines (that you've researched as well).
Try to do as much research as possible before you buy/use and also ensure you have someone who can either be there or check on you, especially if it's your first time. There are plenty of related subreddits RE their use and believe it or not, they're actually quite helpful in terms of dosages and what to expect.
Just to be clear, I'm not trying to scare anyone off…like any substance, we all react differently. I know some swear by ketamine and yeah…not my bag.
Just take things slow, ensure you have a scale, have a trip sitter and stay away from taking too much your first time. Also (and this is important): DO NOT take them if you're in the middle of a depressive episode or you're just overall not feeling well. They have a habit of magnifying what you're feeling and believe me, there is nothing worse than a panic attack * 10 and a depressive episode * 1000. I obviously know where I'm posting and most of us are in a dark place, but coming from a place of experience, do not take them unless you're under the care of a doc or taking actual micro doses.