Help N Enema Vs. Oral

[dumbfarang]

Ok, so I have my n, and I'm trying to decide on whether to use enema or take it orally.

I have both methods all set up, practiced and ready to go, the only thing is that I can't tolerate meto so if I took it orally I would have to take Dramamine.

The risk obviously is if Dramamine will be good enough to prevent vomiting.


In terms of the enema, I can operate it very well (have done a lot of enemas in the past), but there's not as much data on the particular method. It would completely bypass the vomit issue, but idk if it will absorb the same way as it would orally.

Can anyone link to some people/threads who have gone via enema, and anything extra they did with it? Like if they still drank alcohol etc.


One of the worst parts of my condition is the inability to make a decision, so I'm really struggling on which way to do this that would ensure the best possible success rate of ctb.

I need to go soon, and this has to work, so if anyone has any advice or recommendations I'd really appreciate it. Thank you so much

 

[stellabelle]

Here is a thread that discusses n via enema.
https://sanctioned-suicide.net/threads/n-enema.4726/
I believe @Tokyojoe used this method to ctb and was successful.
Here's another thread that discusses an n enema with the use of a plug.

https://sanctioned-suicide.net/threads/n-enema.10033/

I hope this helps.

 

[dumbfarang]

than

Here is a thread that discusses n via enema.
https://sanctioned-suicide.net/threads/n-enema.4726/
I believe @Tokyojoe used this method to ctb and was successful.
Here's another thread that discusses an n enema with the use of a plug.

https://sanctioned-suicide.net/threads/n-enema.10033/

I hope this helps.

thanks stella. are you planning to go this way too?

 

[Chinaski]

Here is a thread that discusses n via enema.
https://sanctioned-suicide.net/threads/n-enema.4726/
I believe @Tokyojoe used this method to ctb and was successful.
Here's another thread that discusses an n enema with the use of a plug.

https://sanctioned-suicide.net/threads/n-enema.10033/

I hope this helps.

Worth remembering that Tokyojoe is not a confirmed passing beyond this site, and used 100ml of dolethal rather than veterinary N.

 

[HannibalLector]

"Horikx warns that the absorption of barbiturates given by supposi-
tory is very unpredictable, especially so in terminal patients. In the
recently updated guidelines of the Royal Dutch Pharmaceutical Society
(2006), the use of suppositories for assisted suicide is strongly discour-
aged." (2006 Guide to Self-Chosen Humane Death, p.77)

Nomenclature
"A suppository is a solid dosage form that is inserted into the rectum (rectal suppository), vagina (vaginal suppository), or urethra (urethral suppository), where it dissolves or melts and exerts local or systemic effects. Suppositories are used to deliver both systemically and locally acting medications."

 

[stellabelle]

than

thanks stella. are you planning to go this way too?

I will likely try to purchase n if I get a passport and go down to Mexico and would be most likely to use the oral method. I do think n is probably the best way to go.

Alternatively, I might use SN or SA instead if I cannot obtain n. I've also pondered hanging, as it can happen quite fast when done properly. I'm hoping to go out on my motorcycle though so my organs can be donated.

 

[dumbfarang]

fuck, this just makes the decision more difficult

 

[OkTotti]

I will likely try to purchase n if I get a passport and go down to Mexico and would be most likely to use the oral method. I do think n is probably the best way to go.

Alternatively, I might use SN or SA instead if I cannot obtain n. I've also pondered hanging, as it can happen quite fast when done properly. I'm hoping to go out on my motorcycle though so my organs can be donated.

Not recommended to go down to Mexico and try and buy N. The locals there aren't keen on selling N. to foreigners. You'll most likely come back empty handed...

 

[sif]

That sounds really interesting, can you miss out the anti vomiting pills then too? When I read the thread title at first I just read it as eNema and I think you should trademark that for the method name

 

[dumbfarang]

That sounds really interesting, can you miss out the anti vomiting pills then too? When I read the thread title at first I just read it as eNema and I think you should trademark that for the method name

ya some other people have named it that lol.

and ya the pro to this method is no anti vommiting pills/no risk of vommiting.

 

[diyCTB]

@dumbfarang How do you know you have Metoclopramide intolerance?

 

[HelensNepenthe]

Not recommended to go down to Mexico and try and buy N. The locals there aren't keen on selling N. to foreigners. You'll most likely come back empty handed...

Interesting. I'd thought they would be open to selling it...

 

[killing me softly]

there are tons of questions on SS about rectal administration of drugs.

i would be very wary of rectal admin of anything unless you have found a medical resource showing it's efficacy.

the fact is there are a lot of factors that are important to consider:
- some drugs have been shown to absorb slower than oral admin, some faster. the rate of absorption for most drugs is not known.
- volume of the drug is going to impact the delivery route too. a small suppository or small amount of liquid will indeed enter the bloodstream directly (and bypass the liver) but a larger amount will enter a upper area of the rectum or colon and will enter the liver and be subject to it's metabolism

from some medical sources:

Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs.
van Hoogdalem E1, de Boer AG, Breimer DD. (PubMed):
"The rate and extent of rectal drug absorption are often lower than with oral absorption, possibly an inherent factor owing to the relatively small surface area available for drug uptake"

Drug Absorption by Sublingual and Rectal Routes
A. G. De Boer, L. G. J. De Leede And D. D. Breimer
The disadvantages associated with administration of drugs rectally include:
(a) interruption of absorption by defaccation, which may occur particularly with irritant drugs;
(b) the surface area of the rectum is far smaller for absorption than that of the duodenum;
(c) the fluid contents of the rectum are much smaller than those of the duodenum and this may produce problems with dissolution of some drugs;
(d) degradation of some drugs by micro-organisms may occur in the rectum;

Rectal drug administration: clinical pharmacokinetic considerations.
de Boer AG, Moolenaar F, de Leede LG, Breimer DD.
"Only limited number of cases has it been adequately shown that the rectal route of administration gives plasma concentrations which are comparable to the oral route."

Exploring the Unconventional Routes — Rectal and Vaginal Dosage Formulations
The Pharmaceutical Journal (A Royal Pharmaceutical Society publication):
"However, drug delivery via the rectal cavity can be challenged by erratic drug absorption due to potential expulsion of the dosage form and low adhesion to the rectal membrane. In addition, drug bioavailability is affected by the site of drug absorption within the rectal cavity. The superior rectal veins go via the liver whereas the inferior rectal veins bypass liver metabolism, thus correct positioning of the dosage form, at the lower rectum, is crucial."

if you are considering this with your method please research it carefully.