Metoclopramide experience

[schopenh]

Hi, I thought I'd share with you guys my experience with metoclopramide.

My plan is to go with the SN method in February (potentially earlier). I was going to use cimetidine, metoclopramide and SN. I was also considering some xanax to knock me out - although I don't want to risk interactions, so I'm not sure I'll do this.

I figured it would be a good idea to test all the meds individually (besides SN of course) just to make sure I don't have an adverse reaction to any.
I should be clear that I'm already on a couple of medications: 80 mg of prednisone (corticosteroid), omeprazole, a proton pump inhibitor (PPIs superceded H2 receptor antagonists like cimetidine), every 2 - 3 days ketamine 75 mg oral solution, every 2 - 3 days some xanax or valium, every 2 - 3 days some tramadol or tapentadol. The ketamine, xanax and opioids I never take on the same day.
I take the pred and omeprazole in the morning after breakfast.

A week ago, a couple of hours after taking my morning meds, I tried 10 mg of metoclopramide. I experienced horrible anxiety, nausea and a headache. I also just felt weak and terrible (more so than usual) for the rest of the day.
I thought it might have been a once off, so I waited a week and a half to trial it again.
Yesterday I tried 20 mg of metoclopramide.
It was horrendous. I had the worst case of anxiety and nervousness I have ever had. I don't suffer from anxiety, just depression, which is itself caused by chronic physical pain. I had the other symptoms as well, and my legs were jittering. I felt so weak.
I could not sleep a wink last night. My mind was positively racing with thoughts. The headache was pretty bad as well.
I tried some valium to calm things down but it didn't help. It just made me physically tired for 2 - 3 hours but didn't calm my mind.

Drug Interaction Report - Drugs.com

www.drugs.com

I checked for interactions between pred, meto and omeprazole and it doesn't appear like there are any.
As it stands I think I'll just be taking 30 mg of meto 50 mins before taking the SN. I don't want to take it for a full two days.

Moral of the story: do a meto trial to see how you react to it.

 

[Hank]

Thanks for sharing that experience.

 

[metalchic_74]

Hi, I thought I'd share with you guys my experience with metoclopramide.

My plan is to go with the SN method in February (potentially earlier). I was going to use cimetidine, metoclopramide and SN. I was also considering some xanax to knock me out - although I don't want to risk interactions, so I'm not sure I'll do this.

I figured it would be a good idea to test all the meds individually (besides SN of course) just to make sure I don't have an adverse reaction to any.
I should be clear that I'm already on a couple of medications: 80 mg of prednisone (corticosteroid), omeprazole, a proton pump inhibitor (PPIs superceded H2 receptor antagonists like cimetidine), every 2 - 3 days ketamine 75 mg oral solution, every 2 - 3 days some xanax or valium, every 2 - 3 days some tramadol or tapentadol. The ketamine, xanax and opioids I never take on the same day.
I take the pred and omeprazole in the morning after breakfast.

A week ago, a couple of hours after taking my morning meds, I tried 10 mg of metoclopramide. I experienced horrible anxiety, nausea and a headache. I also just felt weak and terrible (more so than usual) for the rest of the day.
I thought it might have been a once off, so I waited a week and a half to trial it again.
Yesterday I tried 20 mg of metoclopramide.
It was horrendous. I had the worst case of anxiety and nervousness I have ever had. I don't suffer from anxiety, just depression, which is itself caused by chronic physical pain. I had the other symptoms as well, and my legs were jittering. I felt so weak.
I could not sleep a wink last night. My mind was positively racing with thoughts. The headache was pretty bad as well.
I tried some valium to calm things down but it didn't help. It just made me physically tired for 2 - 3 hours but didn't calm my mind.

Drug Interaction Report - Drugs.com

www.drugs.com

I checked for interactions between pred, meto and omeprazole and it doesn't appear like there are any.
As it stands I think I'll just be taking 30 mg of meto 50 mins before taking the SN. I don't want to take it for a full two days.

Moral of the story: do a meto trial to see how you react to it.

I plan on doing the same.

 

[Neverod]

Thanks for sharing your experience, everyone considering on doing the SN method should do the meto test before, to avoid surprises.
For me, as a dopamine blocker (which gives you pleasure/motivation), there's not a lot of thing i enjoy, and i don't enjoy them anymore thanks to the meto, and a slightly headache, for the rest, it's ok, bearable.

 

[Meant2Die]

Thanks for sharing. I am planning on doing a test as well when I get it. I am also on a lot of medications, more like antibiotics though but I worry how it will affect me. Not to mention due to my chronic illness I'm basically extremely fatigued all the time, I can't be any more fatigued bc then I won't be able to get out of bed or function (or prepare the method), which already happens Sometimes.

I would be really interested in other people's experience from trying me to as well.

 

[mediocre]

I think this is a very good idea. Thank you for sharing. I've already tested the meto and didn't have any reaction to it, but maybe this is because I already feel nauseous and sick on a regular basis and medication doesn't really do anything to help me anyway. I'm sorry to hear you had a bad reaction to it.

 

[JimFord99]

Food for thoughts indeed, thanks schopenh, for addressing this, certainly very helpful.

 

[Meant2Die]

I think this is a very good idea. Thank you for sharing. I've already tested the meto and didn't have any reaction to it, but maybe this is because I already feel nauseous and sick on a regular basis and medication doesn't really do anything to help me anyway. I'm sorry to hear you had a bad reaction to it.

@mediocre where did you get your meto? Just curious bc I was thinking maybe it's a purity issue. maybe his is a fake meto or has a lot of impurities?

 

[JimFord99]

Might be an allergic reaction, who knows?

 

[mediocre]

@mediocre where did you get your meto? Just curious bc I was thinking maybe it's a purity issue. maybe his is a fake meto or has a lot of impurities?

I got mine from the same place as OP. I think from the same seller. I'm pretty confident they are both the real thing from looking at the packaging and blister pack. But who knows for certain. Where have you purchased yours?

 

[Meant2Die]

I got mine from the same place as OP. I think from the same seller. I'm pretty confident they are both the real thing from looking at the packaging and blister pack. But who knows for certain. Where have you purchased yours?

I have not purchased it yet, instead I'm doing research on where people get theirs trying to get a feel for what's a good place. Anyone that says they are using the method and have it, I ask them where they got it. I'm in the US and have seen it on (PM me), but who really knows if it's good. I also saw some people recommend (PM me) but on there it's the HcL version, not sure if that's okay, need to read more.

Edited to hide site names. Pm me if you want to know.

 

[schopenh]

@mediocre where did you get your meto? Just curious bc I was thinking maybe it's a purity issue. maybe his is a fake meto or has a lot of impurities?

It could be fake but I mean, who has the resources to fake a very specific antiemetic and sell them every so often. Doesn't seem like it would be practical

Might be an allergic reaction, who knows?

Could be, as you say, who knows. I'm surprised to hear people above say they felt nothing from it.

 

[Meant2Die]

It could be fake but I mean, who has the resources to fake a very specific antiemetic and sell them every so often. Doesn't seem like it would be practical
.

Very true

 

[SinisterKid]

Please refrain from mentioning sellers, countries of origin, sites, etc etc, see rules. Warnings can and will be given.

 

[Meant2Die]

Not sure if this helps at all but I was just looking at the PPH and the antiemetic section and this is what it says about not tolerating meto....

 

[littlelady774]

I got some Benadryl today. I'm almost afraid to try the meto..

 

[Meant2Die]

Please refrain from mentioning sellers, countries of origin, sites, etc etc, see rules. Warnings can and will be given.

@SinisterKid I'm so sorry, I edited my comment to hide the info. I've seen it listed before which is so helpful vs having to PM all the time for sources, but I understand why its a rule. I'm new here and still learning. There are so many rules its hard to remember , esp for someone like me who has a lot of brain fog due to the meds I'm on. Sorry again.

 

[SinisterKid]

It was aimed at all posters, not anyone specific

 

[schopenh]

It was aimed at all posters, not anyone specific

I apologise. I see it was edited out, thanks.