Meto for SN: Reaction and Interaction with Antidepressants

[Notabadguy]

Meto can cause reaction and it' supposed to be tested before the SN CBT day. It also can cause interaction with antidepressants, on which I am.

What is the solution if that reaction or interaction occurs. That's not been said in PPH neitgervin Stan's Guide.

 

[mimo5555]

It can cause extrapyramidal movement disorders or serotonin syndrome. Those are serious and may requiere urgent care, however the risk of this happening is small.

 

[autumnal]

Meto can cause reaction and it' supposed to be tested before the SN CBT day. It also can cause interaction with antidepressants, on which I am.

What is the solution if that reaction or interaction occurs. That's not been said in PPH neitgervin Stan's Guide.

Have you checked your specific medications in the Drugs.com interactions checker? You can also add SN and any recreational drugs in there to check also.

If you are concerned about reactions, I would definitely recommend you do a test in advance of and separately from your attempt as you mention. Without knowing your specific antidepressants, the main side effect from meto is extrapyrmidal symptoms (EPS) as @mimo5555 mentions, although these are unlikely and generally only temporary based on a single or small number of doses.

If you do a meto test, I would suggest that if possible you create a cover-story with a credible reason why you obtained and took meto (i.e. nausea, migraines etc.). That way in the unlikely event that EPS does occur, and persists to the point where you seek medical help, you will have a reason to avoid any suspicion. However, only the most vigilant medical staff, or your own friends and family, are likely to quiz anyone on the reason for taking a seemingly harmless and legal medication.

 

[Taraxias]

I want to ask if this extrapyramidal movement disorder happens or some other inderaction what is the problem for taking the SN? Either way you just want to die

 

[autumnal]

I want to ask if this extrapyramidal movement disorder happens or some other inderaction what is the problem for taking the SN? Either way you just want to die

I myself have personally wondered whether EPS are that big a deal if they only occur in the relatively short time between consumption of meto (for the stat dose regimen) and unconsciousness from SN, and when they are weighed up against the typical suffering in a life of a suicidal person.

However, in the interest of caution, and because I have not personally experienced EPS nor know how bad it can be at its worst, I would suggest you do the test as described. In the event you don't experience EPS, you are unlikely to do so during your SN protocol either, and you don't need to worry about it further. In the event you do experience EPS, then come back here and the causes and alternatives can be examined further.

 

[charlottewilts]

I want to ask if this extrapyramidal movement disorder happens or some other inderaction what is the problem for taking the SN? Either way you just want to die

there is no problem per se if EPS occurs before you take SN. you should still be able to die if you followed the protocol.

it is merely because people wish to avoid pain and discomfort when they die. SN is popular because it is peaceful when compared to other easily accessible methods.

however, as @autumnal says, it's best to do a test first since EPS adds a variable that is unaccounted for in guides and the PPeH. you might be more likely to call for emergency services, for example.

 

[Giraffey]

I used to take meto and suffered from the EPS symptoms. They are hell on earth, extremely painful muscle cramps that made all of my muscles and joints stiff as well. Even typing became difficult let alone anything that required more dexterity. I could barely walk during the worst of the symptoms. But having said that, it's not particularly common to experience.

If you do experience the EPS and wished to continue anyway, then my advice would be to have everything prepared in advance (so much as you are able). It makes life much easier although EPS symptoms certainly don't make preparation impossible.

 

[Notabadguy]

I used to take meto and suffered from the EPS symptoms. They are hell on earth, extremely painful muscle cramps that made all of my muscles and joints stiff as well. Even typing became difficult let alone anything that required more dexterity. I could barely walk during the worst of the symptoms. But having said that, it's not particularly common to experience.

If you do experience the EPS and wished to continue anyway, then my advice would be to have everything prepared in advance (so much as you are able). It makes life much easier although EPS symptoms certainly don't make preparation impossible.

I want to make a test. How long do the symptoms last?

Have you checked your specific medications in the Drugs.com interactions checker? You can also add SN and any recreational drugs in there to check also.

If you are concerned about reactions, I would definitely recommend you do a test in advance of and separately from your attempt as you mention. Without knowing your specific antidepressants, the main side effect from meto is extrapyrmidal symptoms (EPS) as @mimo5555 mentions, although these are unlikely and generally only temporary based on a single or small number of doses.

If you do a meto test, I would suggest that if possible you create a cover-story with a credible reason why you obtained and took meto (i.e. nausea, migraines etc.). That way in the unlikely event that EPS does occur, and persists to the point where you seek medical help, you will have a reason to avoid any suspicion. However, only the most vigilant medical staff, or your own friends and family, are likely to quiz anyone on the reason for taking a seemingly harmless and legal medication.

Yes, I've just checked in that link, depressants and meto interacts.
Does somebody know how much time in advance I have to stop taking antidepressants in order to they don't interact with the meto?

 

[autumnal]

I want to make a test. How long do the symptoms last?

It all depends on the person and the type and dose of the medications. Hence why it's called a test

Yes, I've just checked in that link, depressants and meto interacts.
Does somebody know how much time in advance I have to stop taking antidepressants in order to they don't interact with the meto?

If you do the test without skipping your regular antidepressants, and using the recommended stat regimen amount of meto, you will get a better idea of whether or not you will even need to consider skipping your antidepressants for your real attempt.

 

[Notabadguy]

It all depends on the person and the type and dose of the medications. Hence why it's called a test



If you do the test without skipping your regular antidepressants, and using the recommended stat regimen amount of meto, you will get a better idea of whether or not you will even need to consider skipping your antidepressants for your real attempt.

I'm taking my regular antidepressant. I did a test with only a meto pill. Nothing strange happened

 

[autumnal]

I'm taking my regular antidepressant. I did a test with only a meto pill. Nothing strange happened

OK. You may wish to increase your meto dose testing up to the stat regimen amount (30mg) of meto (that is assuming you are planning on following the stat dose for your actual attempt).

 

[Notabadguy]

OK. You may wish to increase your meto dose testing up to the stat regimen amount (30mg) of meto (that is assuming you are planning on following the stat regimen for your actual attempt).

Stat regimen.
What I don't like about that us that I want my brain to work properly, I don't want to be sick when I CTB

 

[Krash1990]

Just stop taking your anti depressant a few days before you CTB...

 

[autumnal]

Stat regimen.
What I don't like about that us that I want my brain to work properly, I don't want to be sick when I CTB

Sorry, what you don't like about what?

Just stop taking your anti depressant a few days before you CTB...

Not necessarily. This may lead to problematic withdrawal symptoms.

 

[Krash1990]

Sorry, what you don't like about what?



Not necessarily. This may lead to problematic withdrawal symptoms.

Many antidepressants are not going to give you withdrawals for 2-3 days..

Stopping for a day or two is only going to lower the concentration enough to not risk EPS anywhere near a worthwhile thought and still not leave you with significant withdrawals symptoms.

 

[enjolras]

Stat regimen is stat or regimen (preloading) ?

I want to make a test. How long do the symptoms last?

Yes, I've just checked in that link, depressants and meto interacts.
Does somebody know how much time in advance I have to stop taking antidepressants in order to they don't interact with the meto?

I did both stat & regimen tests.

Stat was always fine (2 times, low & high dose; & kicking late, like not before the 1 hour mark. So no problem to CTB

However, the regimen was a whole lot different story. Between the 2nd & 3rd intakes, it started to make me really depressed, anxious & agitated with a weird fuzzy headache ...turned me very suicidal, about to break. I couldn't focus & think anymore, like my mind was on block and my thoughts sucked out rapidly (I really felt brainless, it brought me to tears). It scared and was strong. Apparently, this is one of the possible commonest reaction, according to the FDA, and I really took it in the face !





Ironic ? Like an encouragement ...but not nice at all. I'll choose stat.

 

[Weightoftheworld]

I'm glad to read this, I've been iffy on trying to get meto from my doctor. I take antidepressants and epilepsy medicine so I doubt she would give it to me, the risks of combining the meds are moderate. Plus I don't want any additional tests done if I tell my dr or neuro I'm having migraines.

 

[autumnal]

Stat regimen is stat or regimen (preloading) ?

Corrected

Many antidepressants are not going to give you withdrawals for 2-3 days..

Stopping for a day or two is only going to lower the concentration enough to not risk EPS anywhere near a worthwhile thought and still not leave you with significant withdrawals symptoms.

Still, it does depend on the particular medication and dosage and it's certainly possible for discontinuation syndrome to occur within a shorter timeframe. 2 to 3 days is the typical maximum time of onset, not the minimum. With nausea and vomiting being one of the possible withdrawal symptoms, it does have direct relevance to the SN method.

I am not an expert, but I personally would suggest testing the stat dose amount of meto while continuing regular antidepressant dosage and timing. In the event that no EPS develop from that test, I would recommend continuing regular antidepressant dosage in conjunction with the stat dose of meto and the SN. If EPS did develop from the test, then the OP would need to report back and we would examine and discuss the options further, in which case tapering off antidepressant dosage could be one option to consider.