Help least painful way to die ever?

[swatted]

title

 

[longtime_lurker_123]

Here is a list of suicide methods and their success rate (you're welcome)

sanctioned-suicide.net

 

[Lyn]

You would probably want to check the PPH to have an idea.

PPH January 2025

https://gofile.io/d/EwPVlE (link has preview)

sanctioned-suicide.net

But if it's a broader question...

I'd say being in the VIP section of a nuclear blast.
Mere milliseconds to disappear completely.

 

[wanttodie]

Here is a list of suicide methods and their success rate (you're welcome)

sanctioned-suicide.net

thanks

 

[MathConspiracy]

Barbiturates… Wish I was Marilyn.

 

[Intoxicated]

Here is a list of suicide methods and their success rate (you're welcome)

sanctioned-suicide.net

Thanks for the link, the comments on those ratings are just It's amazing how intelligent forum users were back then.

 

[FuneralCry]

For me it'd be a painless poison that gives me a death like falling into an permanent sleep as all I hope for is to never wake ever again, I wish for no more pain, no more suffering rather I just want all to be gone and forgotten for me, for me the only relief could lie in never existing eve again, I just want to finally forget about this existence I personally always saw as a mistake and I'd just never wish to suffer in this existence no matter what, I always suffer so much from being denied such a way to cease existing.

 

[RadiantNumber]

I wonder if there is such thing, as I see descriptions of deaths from SS, even as I read this one describing suicide with SN (one user of this forum posted his observation of other user from this user using this method and after reading idk if I would use this method, but this is my personal opinion)

 

[Freebandzgang]

Dying in your sleep. Doesnt matter the method, if you are sleeping/unconscious you wont feel any pain.

 

[Foolishness]

Dying in your sleep. Doesnt matter the method, if you are sleeping/unconscious you wont feel any pain.

Would love to have a lethal seizure in my sleep.

 

[Halfhourdays]

Gun, probably.

 

[RadiantNumber]

Dying in your sleep. Doesnt matter the method, if you are sleeping/unconscious you wont feel any pain.

Opioids could make you die in sleep but I don't know if you feel choking, in Breaking Bad it was scary

 

[gothbird]

Here's the reality: there is no such thing as a truly pain-free death—because the body is built to resist death with everything it has. Even in unconsciousness, your brain and nerves are often still firing signals. However, there are methods that are significantly less painful, both physically and psychologically, than others.

---

1. Inert Gas Asphyxiation (e.g. Nitrogen or Helium)

Why it's low-pain:
Inhaling an inert gas like nitrogen displaces oxygen in the lungs without triggering the panic or "air hunger" response, because the brain doesn't detect rising CO₂ levels (which is what usually causes the feeling of suffocation). This leads to hypoxia and unconsciousness within 10–15 seconds, with death following shortly after.

Scientific basis:
The absence of CO₂ buildup is key. CO₂—not lack of oxygen—is what triggers the sense of suffocation. In clinical settings, patients accidentally exposed to nitrogen have lost consciousness without distress.

Downside:
Requires precision, proper equipment, and understanding of gas flow rates and mask sealing. Risk of partial survival or brain damage if done incorrectly.

---

2. Sodium Nitrite (SN) Ingestion

Why it's low-pain:
SN induces methemoglobinemia, which reduces the blood's ability to carry oxygen. Unlike standard hypoxia, it doesn't create the same air hunger, and loss of consciousness usually occurs within 20–40 minutes, with death occurring shortly after (usually under 2 hours). Nausea and vomiting can occur, but antiemetics reduce this.

Scientific basis:
SN interferes with hemoglobin's oxygen transport by converting it into methemoglobin. The body essentially suffocates at the cellular level, while the brain is slowly deprived of oxygen. Animal and human overdose cases often describe lightheadedness and sedation prior to collapse.

Downside:
Nausea, potential vomiting, requires careful dosing and timing of antiemetics. Incomplete doses can result in survival with organ damage.

---

3. Barbiturate Overdose (Pentobarbital, Secobarbital)

Why it's low-pain:
Barbiturates depress the central nervous system quickly and deeply. When taken in lethal doses, they cause sedation, coma, and respiratory arrest with minimal perceived pain.

Scientific basis:
Used in medically assisted death (e.g. Dignitas, euthanasia clinics). Unconsciousness typically occurs within minutes, followed by death in under an hour.

Downside:
No legal access in most countries. Difficult or impossible to obtain without connections or travel.

---

Methods That Seem Painless But Aren't:

• Opioid overdose: Often romanticised. In reality, vomiting, seizures, or respiratory panic can occur before death. High tolerance may also make it ineffective.
• Hanging: Extremely variable. Quick neck breaks are rare. Most deaths are slow strangulation with high panic and pain.
• Carbon monoxide (CO): Painful headaches, nausea, and long exposure times are common. Also dangerous for others and hard to control with modern alarms.

 

[Freebandzgang]

Even in unconsciousness, your brain and nerves are often still firing signals

Yes your brain is still subconsciously working, but you wont feel any pain, the pain could wake you up or make you do something subconsciously but you wont feel it. The only problem is that if the pain is prolonged it will likely wake you up and then you would feel it. Great post btw

 

[RadiantNumber]

Here's the reality: there is no such thing as a truly pain-free death—because the body is built to resist death with everything it has. Even in unconsciousness, your brain and nerves are often still firing signals. However, there are methods that are significantly less painful, both physically and psychologically, than others.

---

1. Inert Gas Asphyxiation (e.g. Nitrogen or Helium)

Why it's low-pain:
Inhaling an inert gas like nitrogen displaces oxygen in the lungs without triggering the panic or "air hunger" response, because the brain doesn't detect rising CO₂ levels (which is what usually causes the feeling of suffocation). This leads to hypoxia and unconsciousness within 10–15 seconds, with death following shortly after.

Scientific basis:
The absence of CO₂ buildup is key. CO₂—not lack of oxygen—is what triggers the sense of suffocation. In clinical settings, patients accidentally exposed to nitrogen have lost consciousness without distress.

Downside:
Requires precision, proper equipment, and understanding of gas flow rates and mask sealing. Risk of partial survival or brain damage if done incorrectly.

---

2. Sodium Nitrite (SN) Ingestion

Why it's low-pain:
SN induces methemoglobinemia, which reduces the blood's ability to carry oxygen. Unlike standard hypoxia, it doesn't create the same air hunger, and loss of consciousness usually occurs within 20–40 minutes, with death occurring shortly after (usually under 2 hours). Nausea and vomiting can occur, but antiemetics reduce this.

Scientific basis:
SN interferes with hemoglobin's oxygen transport by converting it into methemoglobin. The body essentially suffocates at the cellular level, while the brain is slowly deprived of oxygen. Animal and human overdose cases often describe lightheadedness and sedation prior to collapse.

Downside:
Nausea, potential vomiting, requires careful dosing and timing of antiemetics. Incomplete doses can result in survival with organ damage.

---

3. Barbiturate Overdose (Pentobarbital, Secobarbital)

Why it's low-pain:
Barbiturates depress the central nervous system quickly and deeply. When taken in lethal doses, they cause sedation, coma, and respiratory arrest with minimal perceived pain.

Scientific basis:
Used in medically assisted death (e.g. Dignitas, euthanasia clinics). Unconsciousness typically occurs within minutes, followed by death in under an hour.

Downside:
No legal access in most countries. Difficult or impossible to obtain without connections or travel.

---

Methods That Seem Painless But Aren't:

• Opioid overdose: Often romanticised. In reality, vomiting, seizures, or respiratory panic can occur before death. High tolerance may also make it ineffective.
• Hanging: Extremely variable. Quick neck breaks are rare. Most deaths are slow strangulation with high panic and pain.
• Carbon monoxide (CO): Painful headaches, nausea, and long exposure times are common. Also dangerous for others and hard to control with modern alarms.

What about fentanyl I heard one touch could kill or something

 

[gothbird]

Yes your brain is still subconsciously working, but you wont feel any pain, the pain could wake you up or make you do something subconsciously but you wont feel it. The only problem is that if the pain is prolonged it will likely wake you up and then you would feel it. Great post btw

Solid clarification. The brain does keep running background systems even in altered states, and you're right: pain signals can still activate motor responses or trigger fight/flight reflexes before full unconsciousness. That's why some methods that seem peaceful can backfire if they're too slow or allow for prolonged discomfort—because you might not consciously register it, but your body does, and that can be enough to jolt you back.

Short duration pain? Probably won't matter. But anything extended? That's where the risk of waking, panic, or reflexive survival kicks in.

Appreciate you adding this—more people need to understand that "not feeling it" isn't always the same as "not reacting to it."

What about fentanyl I heard one touch could kill or something

That whole "one touch and you're dead" thing? It's mostly media fearmongering. You're not going to die from touching fentanyl unless you're exposed to a large amount in aerosol or powder form and inhale it directly. Skin contact alone, especially brief, isn't enough to cause an overdose. Even emergency responders have walked that back after the initial panic headlines.

As for using fentanyl as a method: it can be lethal, but it's not reliable unless you know exactly what you're doing. There's a high risk of survival with brain damage if dosing isn't precise. Plus, it's often mixed with other substances unless it's pharmaceutical-grade, which makes it even harder to calculate.

It's not the clean, instant fade people imagine. Respiratory depression takes time, and many people vomit, seize, or panic before losing consciousness. Some survive with permanent damage. Some die horribly.

So yeah—possible, but not as peaceful or foolproof as it's often made out to be.

 

[RadiantNumber]

I also saw (but only saw, this is not my claim) that nicotine extracted from tobbaco is powerful killer

 

[gothbird]

I also saw (but only saw, this is not my claim) that nicotine extracted from tobbaco is powerful killer

Yeah, that one actually has a bit of truth to it. Pure nicotine like the kind extracted or synthesized in a lab is highly toxic in small doses. We're talking milligram level lethal. Historically, it's been used as an insecticide and even considered for use as a poison. The estimated lethal dose for an adult is somewhere around 30–60mg.

But getting that dose reliably is not easy outside of a lab. Extracting pure nicotine from tobacco requires serious chemistry knowledge, and messing it up could just make you violently ill without killing you.

 

[NoMoreSanity]

In your sleep.

 

[RadiantNumber]

Yeah, that one actually has a bit of truth to it. Pure nicotine like the kind extracted or synthesized in a lab is highly toxic in small doses. We're talking milligram level lethal. Historically, it's been used as an insecticide and even considered for use as a poison. The estimated lethal dose for an adult is somewhere around 30–60mg.

But getting that dose reliably is not easy outside of a lab. Extracting pure nicotine from tobacco requires serious chemistry knowledge, and messing it up could just make you violently ill without killing you.

I see and what about drinking liquid, sorry for stupid question, just asking

 

[gothbird]

I see and what about drinking liquid, sorry for stupid question, just asking

Not a stupid question.

If you're asking about drinking nicotine in liquid form (like nicotine sulfate or extracted concentrate), yes—that can be fatal, but it's also extremely dangerous, painful, and unpredictable. Even tiny amounts can cause violent vomiting, convulsions, respiratory distress, and, if the dose isn't high enough, survival with severe organ or brain damage. Like most things.
The body absorbs liquid nicotine rapidly through the stomach and lining of the mouth, but it also fights back hard. People have survived what should've been fatal doses just because the vomiting was so immediate and intense.

Curiosity is okay. Just make sure it leads you somewhere informed. I'm not a chemist, just a housebound obsessive with access to too many journals and too much time. I read. A lot.

 

[RadiantNumber]

Not a stupid question.

If you're asking about drinking nicotine in liquid form (like nicotine sulfate or extracted concentrate), yes—that can be fatal, but it's also extremely dangerous, painful, and unpredictable. Even tiny amounts can cause violent vomiting, convulsions, respiratory distress, and, if the dose isn't high enough, survival with severe organ or brain damage. Like most things.
The body absorbs liquid nicotine rapidly through the stomach and lining of the mouth, but it also fights back hard. People have survived what should've been fatal doses just because the vomiting was so immediate and intense.

Curiosity is okay. Just make sure it leads you somewhere informed. I'm not a chemist, just a housebound obsessive with access to too many journals and too much time. I read. A lot.

Thanks I wanted to try this
I assume this also include patches gums etc
You must be chemist to properly kill yourself

 

[gothbird]

Thanks I wanted to try this
I assume this also include patches gums etc
You must be chemist to properly kill yourself

Patches and gums won't do it. They deliver too little nicotine too slowly.
And honestly? You don't have to be a chemist, but you do have to think like one. The margin for error with certain substances is razor thin. One decimal off and you're either surviving in agony or waking up in a hospital bed with a destroyed liver.
Precision matters. Method matters. Curiosity's fine but if you're serious, research is non-negotiable.

 

[frommolecules2stars]

I found this thread to be helpful.

What's in your suicide kit? I study pharmacology

Propofol is enough as a single agent. But still I can mix others with propofol. Propofol + bupivacine, propofol + lidocaine or propofol + digoxin. Other drugs are just in the bag. I will not use them. I have an injection system that I can inject 1800 mg propofol to myself. This is enough alone...

sanctioned-suicide.net

 

[Intoxicated]

Here's the reality: there is no such thing as a truly pain-free death—because the body is built to resist death with everything it has.

Death from a powerful rifle bullet in the head may be deemed truly pain-free. The brain is destroyed so quickly that it wouldn't be able to process any pain.

Death from asphyxiation with a non-irritating simple asphyxiant is likely pain-free too, as long as the body is not disturbed between LOC and deep unconsciousness.

1. Inert Gas Asphyxiation (e.g. Nitrogen or Helium)

...This leads to hypoxia and unconsciousness within 10–15 seconds

Unconsciousness in 10 - 15 s is too fast for a healthy adult. Even if you hyperventilate when breathing with an inert gas, complete loss of consciousness will likely happen after more than 15 s, although the onset of asphyxiation symptoms may (but is not guaranteed to) occur within the range you mentioned. Those who attempt to CTB with such a method shouldn't worry if they don't notice any changes within 15 seconds of breathing the oxygen-depleted gas.

• Carbon monoxide (CO): Painful headaches, nausea, and long exposure times are common.

I have doubts about having such issues under exposure to ≥5% CO that can be reliably produced with some appropriate chemical reactions (like HCOONa + conc. H2SO4) and an optimal delivery of the gas to the respiratory tract (e.g. with a plastic bag over the head)

 

[pthnrdnojvsc]

Death from a powerful rifle bullet in the head may be deemed truly pain-free. The brain is destroyed so quickly that it wouldn't be able to process any pain.

Death from asphyxiation with a non-irritating simple asphyxiant is likely pain-free too, as long as the body is not disturbed between LOC and deep unconsciousness.

Unconsciousness in 10 - 15 s is too fast for a healthy adult. Even if you hyperventilate when breathing with an inert gas, complete loss of consciousness will likely happen after more than 15 s, although the onset of asphyxiation symptoms may (but is not guaranteed to) occur within the range you mentioned. Those who attempt to CTB with such a method shouldn't worry if they don't notice any changes within 15 seconds of breathing the oxygen-depleted gas.

I have doubts about having such issues under exposure to ≥5% CO that can be reliably produced with some appropriate chemical reactions (like HCOONa + conc. H2SO4) and an optimal delivery of the gas to the respiratory tract (e.g. with a plastic bag over the head)

i agree .

a rifle , shotgun will destroy the brain before the brain can register any pain. these bullets travel a thousands of feet per second. even amongh the slowest will travel 1000 feet per second. so it will travel 1 foot in a milisecond destroying the brain in that milisecond. a meter is about 3 feet. the brain can't process pain in a milisecond

Simulation Reveals Exactly How Titan Submersible Imploded - Engineering.com

For the victims, no time to panic and a painless death.

www.engineering.com

"This was a catastrophic implosion of the vessel," said Rear Adm. John Mauger of the First Coast Guard District.


It may be of little consolation to the families of the victims of the Titan submersible that the implosion of the vessel took milliseconds. In that short amount of time, the brain cannot process pain. This is according to Dr. Chris Raynor, an orthopedic surgeon and YouTube star. In his viral video, now watched 2.8 million times, Raynor offers a sequence of events that results in pain sensation.


"There is a general process involved with feeling pain: first nerve endings called nociceptors detect pain usually within 0.1 to 1 millisecond; signals then travel to the spinal cord through nerve fibers, taking approximately 5 to 50 milliseconds; initial neural processing occurs in the spinal cord taking around 3 to 10 milliseconds; and finally the brain processes the signals and pain is perceived within tens to hundreds of milliseconds.

 

[gothbird]

Death from a powerful rifle bullet in the head may be deemed truly pain-free. The brain is destroyed so quickly that it wouldn't be able to process any pain.

Death from asphyxiation with a non-irritating simple asphyxiant is likely pain-free too, as long as the body is not disturbed between LOC and deep unconsciousness.

Unconsciousness in 10 - 15 s is too fast for a healthy adult. Even if you hyperventilate when breathing with an inert gas, complete loss of consciousness will likely happen after more than 15 s, although the onset of asphyxiation symptoms may (but is not guaranteed to) occur within the range you mentioned. Those who attempt to CTB with such a method shouldn't worry if they don't notice any changes within 15 seconds of breathing the oxygen-depleted gas.

I have doubts about having such issues under exposure to ≥5% CO that can be reliably produced with some appropriate chemical reactions (like HCOONa + conc. H2SO4) and an optimal delivery of the gas to the respiratory tract (e.g. with a plastic bag over the head)

Solid breakdown overall. I agree—rifle to the head, assuming correct placement and sufficient calibre, is about as close to instantaneous as death gets. Destruction of the brainstem and upper cortex in milliseconds means there's likely no time for pain processing at all. It's just off.

Re: inert gas asphyxiation, yeah, "unconscious in 10–15 seconds" is the best-case estimate based on hypoxia onset from case studies and some anecdotal reports. In reality, for healthy adults, you're more likely looking at 30+ seconds for noticeable disorientation, with full LOC closer to the 45–60 second mark. Hyperventilating beforehand speeds it up a little by dropping CO₂ levels, but it doesn't make it instant.

You're right that the absence of panic cues (like air hunger) is the real reason inert gases are tolerable. The body doesn't register suffocation if CO₂ doesn't rise—just a gradual fade. People attempting this shouldn't panic if nothing dramatic happens in 15 seconds. That's normal.

As for CO at 5%+ concentrations—with controlled delivery, yeah, it's fatal. But it's still a very messy gas to generate safely. And unless you have lab-grade conditions and proper seals, you're risking long, uneven exposure and nausea. Add in the headache, pinkish discoloration, and potential for rescue if anyone smells something or hears a generator, and it loses a lot of appeal.

Still, I respect the chemistry here. Just important to remember: low-panic ≠ low-risk. The most peaceful methods still come with variables. Nothing's flawless.

 

[aiyuxhan]

You would probably want to check the PPH to have an idea.

PPH January 2025

https://gofile.io/d/EwPVlE (link has preview)

sanctioned-suicide.net

But if it's a broader question...

I'd say being in the VIP section of a nuclear blast.
Mere milliseconds to disappear completely.

Nuclear blast would be awesome lol

 

[lifeisbutadream]

I read that breathing nitrogen is so painless that when they tested it on animals, goats I believe, they were happily munching grass and then suddenly fell down dead.

 

[Intoxicated]

inert gas asphyxiation, yeah, "unconscious in 10–15 seconds" is the best-case estimate based on hypoxia onset from case studies and some anecdotal reports.

Can you provide any study reporting unconsciousness in under 15 seconds? The best results I've seen are 16 - 17 seconds or 17 - 20 seconds for unconsciousness and 12 - 14 seconds for the onset of symptoms from over-ventilation with nitrogen

https://i.sanctioned-suicide.net/images/2025/04/224188_ernsting1963.pdf