Method CTB by disulfiram reaction

[peace_van]

Just an idea, disulfiram reaction can be induced by taking easily obtained drugs like Cephalosporin and then drink a certain volume of alcohol.
Simply put, the drug inhibits the metabolism of alcohol and increases its toxicity.
It can be lethal when consumed in large amount, though the rate and required dosage need further research.
The advantage of this method is that the materials are easy to get and no special gears or equipment is needed.
The pain may be tolerable I think, it's like being forced into a deep drunk state.

What do you think about this method? Does anyone have further information on this method?

 

[Praestat_Mori]

I don't think it's a very reliable method. If it was it would be discussed more. It depends only on metabolism of the ethanol (which is alc. we drink with beer, spirits and so on) into acetaldehyd (H3C-CHO) which is poisonous. Disulfiram blocks the metabolism of acetaldehyd which leads to the poisoning.

The symptoms seem to be very unpleasant and death isn't guaranteed in any case with this method.

 

[anaerobic_bacterium]

interesting. when ethanol consumed it breaks down into acetaldehyde it follows that it's the main compound responsible for ethanol toxicity. the disulfram reaction renders the acetaldehyde neutralization by ALDH useless for this reason the substance conc. in the blood skyrocket.

the ld50 for acetaldehyde in rats is 2gm/kg, given that all ethanol metabolized into acetaldehyde we can downsize the amount of ethanol required to attain a lethal outcome from 400g-600g (4 bottles of vodka) per person of normal weight to just 120g (around 1 bottle of vodka of 500ml)